{"id":197455,"name":null,"description":"Thermodynamically Motivated Enrichment Analysis (TMEA) is a new approach to gene set enrichment analysis.","url":"https://github.com/csbiology/tmea","last_synced_at":"2025-09-10T05:02:38.151Z","repository":{"id":46656609,"uuid":"287800059","full_name":"CSBiology/TMEA","owner":"CSBiology","description":"Thermodynamically Motivated Enrichment Analysis (TMEA) is a new approach to gene set enrichment analysis.","archived":false,"fork":false,"pushed_at":"2023-01-03T11:57:25.000Z","size":11097,"stargazers_count":8,"open_issues_count":8,"forks_count":3,"subscribers_count":3,"default_branch":"main","last_synced_at":"2025-09-07T17:57:10.608Z","etag":null,"topics":["bioinformatics","biostatistics","deedle","enrichment-score","f-sharp","genes","gsea","plotly"],"latest_commit_sha":null,"homepage":"https://www.mdpi.com/1099-4300/22/9/1030","language":"F#","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":"mit","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/CSBiology.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":"LICENSE","code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null}},"created_at":"2020-08-15T18:09:12.000Z","updated_at":"2024-01-17T21:37:31.000Z","dependencies_parsed_at":"2023-02-01T06:01:10.098Z","dependency_job_id":null,"html_url":"https://github.com/CSBiology/TMEA","commit_stats":null,"previous_names":[],"tags_count":2,"template":false,"template_full_name":null,"purl":"pkg:github/CSBiology/TMEA","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/CSBiology","download_url":"https://codeload.github.com/CSBiology/TMEA/tar.gz/refs/heads/main","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/sbom","scorecard":null,"host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":274415190,"owners_count":25280711,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","status":"online","status_checked_at":"2025-09-10T02:00:12.551Z","response_time":83,"last_error":null,"robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":true,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"owner":null,"packages":[{"id":9089975,"name":"tmea","ecosystem":"nuget","description":"TMEA (Thermodynamically Motivated Enrichment Analysis) is a thermodynamically motivated approach to gene set enrichment analysis","homepage":"https://csbiology.github.io/TMEA","licenses":"MIT","normalized_licenses":["MIT"],"repository_url":"https://github.com/csbiology/TMEA","keywords_array":["F#","FSharp","bioinformatics","biostatistics","datascience","biology","GSEA","geneset-enrichment-analysis"],"namespace":null,"versions_count":10,"first_release_published_at":"2020-08-16T22:31:03.247Z","latest_release_published_at":"2022-07-21T15:50:12.207Z","latest_release_number":"0.6.0","last_synced_at":"2025-09-02T08:50:48.259Z","created_at":"2024-02-27T07:08:34.681Z","updated_at":"2025-09-02T10:19:25.546Z","registry_url":"https://www.nuget.org/packages/tmea/","install_command":"Install-Package tmea","documentation_url":null,"metadata":{"license_info":{"type":"expression","text":"MIT","version":null},"license_url":"https://licenses.nuget.org/MIT","require_license_acceptance":false,"icon":"logo.png","repository":{"type":"git","url":"https://github.com/CSBiology/TMEA","branch":null,"commit":"aefcec50b3ef216244e015cf3fba72d1d04749ec"},"development_dependency":false,"serviceable":false,"framework_assemblies":[],"package_types":[],"release_notes":"- [PR #9](https://github.com/CSBiology/TMEA/pull/9) by [@bvenn](https://github.com/bvenn):\n- fixed a bug that mixed up some results concerning the significance matrix creation.\n- added the possibility to choose between q vaalue, benjamini hochberg, or no multiple testing correction","dependency_summary":{"total_dependency_groups":1,"target_frameworks":[".NETStandard2.0"],"total_dependencies":8}},"repo_metadata":{"id":46656609,"uuid":"287800059","full_name":"CSBiology/TMEA","owner":"CSBiology","description":"Thermodynamically Motivated Enrichment Analysis (TMEA) is a new approach to gene set enrichment analysis.","archived":false,"fork":false,"pushed_at":"2023-01-03T11:57:25.000Z","size":11097,"stargazers_count":8,"open_issues_count":8,"forks_count":3,"subscribers_count":3,"default_branch":"main","last_synced_at":"2025-08-30T09:52:28.650Z","etag":null,"topics":["bioinformatics","biostatistics","deedle","enrichment-score","f-sharp","genes","gsea","plotly"],"latest_commit_sha":null,"homepage":"https://www.mdpi.com/1099-4300/22/9/1030","language":"F#","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":"mit","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/CSBiology.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":"LICENSE","code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null}},"created_at":"2020-08-15T18:09:12.000Z","updated_at":"2024-01-17T21:37:31.000Z","dependencies_parsed_at":"2023-02-01T06:01:10.098Z","dependency_job_id":null,"html_url":"https://github.com/CSBiology/TMEA","commit_stats":null,"previous_names":[],"tags_count":2,"template":false,"template_full_name":null,"purl":"pkg:github/CSBiology/TMEA","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/CSBiology","download_url":"https://codeload.github.com/CSBiology/TMEA/tar.gz/refs/heads/main","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/sbom","scorecard":null,"host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":273267542,"owners_count":25075256,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","status":"online","status_checked_at":"2025-09-02T02:00:09.530Z","response_time":77,"last_error":null,"robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":true,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"},"owner_record":{"login":"CSBiology","name":"Computational Systems Biology","uuid":"16578616","kind":"organization","description":"Computational Systems Biology ","email":null,"website":"https://csb.bio.uni-kl.de/","location":"Kaiserslautern","twitter":"cs_biology","company":null,"icon_url":"https://avatars.githubusercontent.com/u/16578616?v=4","repositories_count":48,"last_synced_at":"2024-03-19T06:00:31.964Z","metadata":{"has_sponsors_listing":false},"html_url":"https://github.com/CSBiology","funding_links":[],"total_stars":415,"followers":null,"following":null,"created_at":"2022-11-09T02:09:43.309Z","updated_at":"2024-03-19T06:00:40.624Z","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/CSBiology","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/CSBiology/repositories"},"tags":[{"name":"0.6.0","sha":"aefcec50b3ef216244e015cf3fba72d1d04749ec","kind":"commit","published_at":"2022-07-21T15:49:31.000Z","download_url":"https://codeload.github.com/CSBiology/TMEA/tar.gz/0.6.0","html_url":"https://github.com/CSBiology/TMEA/releases/tag/0.6.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/CSBiology/TMEA@0.6.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/tags/0.6.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/tags/0.6.0/manifests"},{"name":"0.1.0-beta","sha":"8a9a6ba4c77c0e52426cd6aad7fb562844e392a6","kind":"commit","published_at":"2020-09-07T22:17:29.000Z","download_url":"https://codeload.github.com/CSBiology/TMEA/tar.gz/0.1.0-beta","html_url":"https://github.com/CSBiology/TMEA/releases/tag/0.1.0-beta","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/CSBiology/TMEA@0.1.0-beta","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/tags/0.1.0-beta","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/tags/0.1.0-beta/manifests"}]},"repo_metadata_updated_at":"2025-09-02T10:19:25.546Z","dependent_packages_count":0,"downloads":3811,"downloads_period":"total","dependent_repos_count":0,"rankings":{"downloads":32.041012542180844,"dependent_repos_count":10.161582250766312,"dependent_packages_count":13.885856079404466,"stargazers_count":null,"forks_count":null,"docker_downloads_count":null,"average":18.696150290783873},"purl":"pkg:nuget/tmea","advisories":[],"docker_usage_url":"https://docker.ecosyste.ms/usage/nuget/tmea","docker_dependents_count":null,"docker_downloads_count":null,"usage_url":"https://repos.ecosyste.ms/usage/nuget/tmea","dependent_repositories_url":"https://repos.ecosyste.ms/api/v1/usage/nuget/tmea/dependencies","status":null,"funding_links":[],"critical":null,"issue_metadata":{"last_synced_at":"2025-06-24T01:52:15.692Z","issues_count":10,"pull_requests_count":2,"avg_time_to_close_issue":10812325.333333334,"avg_time_to_close_pull_request":185193.0,"issues_closed_count":3,"pull_requests_closed_count":1,"pull_request_authors_count":1,"issue_authors_count":2,"avg_comments_per_issue":0.2,"avg_comments_per_pull_request":0.0,"merged_pull_requests_count":1,"bot_issues_count":0,"bot_pull_requests_count":0,"past_year_issues_count":0,"past_year_pull_requests_count":0,"past_year_avg_time_to_close_issue":null,"past_year_avg_time_to_close_pull_request":null,"past_year_issues_closed_count":0,"past_year_pull_requests_closed_count":0,"past_year_pull_request_authors_count":0,"past_year_issue_authors_count":0,"past_year_avg_comments_per_issue":null,"past_year_avg_comments_per_pull_request":null,"past_year_bot_issues_count":0,"past_year_bot_pull_requests_count":0,"past_year_merged_pull_requests_count":0,"issues_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/issues","maintainers":[{"login":"kMutagene","count":8,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/kMutagene"},{"login":"bvenn","count":4,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/bvenn"}],"active_maintainers":[]},"versions_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/packages/tmea/versions","version_numbers_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/packages/tmea/version_numbers","dependent_packages_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/packages/tmea/dependent_packages","related_packages_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/packages/tmea/related_packages","maintainers":[{"uuid":"Mutagene","login":"Mutagene","name":null,"email":null,"url":null,"packages_count":35,"html_url":"https://www.nuget.org/profiles/Mutagene","role":null,"created_at":"2024-02-27T07:13:13.315Z","updated_at":"2024-02-27T07:13:13.315Z","packages_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/maintainers/Mutagene/packages"},{"uuid":"Muehlhaus","login":"Muehlhaus","name":null,"email":null,"url":null,"packages_count":16,"html_url":"https://www.nuget.org/profiles/Muehlhaus","role":null,"created_at":"2024-02-27T07:13:13.282Z","updated_at":"2024-02-27T07:13:13.282Z","packages_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/maintainers/Muehlhaus/packages"},{"uuid":"CSBiology","login":"CSBiology","name":null,"email":null,"url":null,"packages_count":82,"html_url":"https://www.nuget.org/profiles/CSBiology","role":null,"created_at":"2024-02-27T07:13:13.239Z","updated_at":"2024-02-27T07:13:13.239Z","packages_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/maintainers/CSBiology/packages"},{"uuid":"bvenn","login":"bvenn","name":null,"email":null,"url":null,"packages_count":2,"html_url":"https://www.nuget.org/profiles/bvenn","role":null,"created_at":"2024-02-27T07:13:13.169Z","updated_at":"2024-02-27T07:13:13.169Z","packages_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/maintainers/bvenn/packages"}],"registry":{"name":"nuget.org","url":"https://www.nuget.org","ecosystem":"nuget","default":true,"packages_count":740865,"maintainers_count":102618,"namespaces_count":0,"keywords_count":152383,"github":"nuget","metadata":{"funded_packages_count":25514},"icon_url":"https://github.com/nuget.png","created_at":"2022-04-04T15:19:23.147Z","updated_at":"2025-09-09T06:17:09.058Z","packages_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/packages","maintainers_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/maintainers","namespaces_url":"https://packages.ecosyste.ms/api/v1/registries/nuget.org/namespaces"}}],"commits":{"id":7300585,"full_name":"csbiology/tmea","default_branch":"master","committers":null,"total_commits":null,"total_committers":null,"total_bot_commits":null,"total_bot_committers":null,"mean_commits":null,"dds":null,"past_year_committers":null,"past_year_total_commits":null,"past_year_total_committers":null,"past_year_total_bot_commits":null,"past_year_total_bot_committers":null,"past_year_mean_commits":null,"past_year_dds":null,"last_synced_at":null,"last_synced_commit":null,"created_at":"2024-12-04T22:13:24.968Z","updated_at":"2024-12-04T22:13:24.968Z","commits_url":"https://commits.ecosyste.ms/api/v1/hosts/GitHub/repositories/csbiology%2Ftmea/commits","host":{"name":"GitHub","url":"https://github.com","kind":"github","last_synced_at":"2025-09-10T00:25:43.995Z","repositories_count":5545114,"commits_count":878229909,"contributors_count":32458717,"owners_count":919815,"icon_url":"https://github.com/github.png","host_url":"https://commits.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://commits.ecosyste.ms/api/v1/hosts/GitHub/repositories"}},"issues_stats":{"full_name":"CSBiology/TMEA","html_url":"https://github.com/CSBiology/TMEA","last_synced_at":"2025-06-24T01:52:15.692Z","status":null,"issues_count":10,"pull_requests_count":2,"avg_time_to_close_issue":10812325.333333334,"avg_time_to_close_pull_request":185193.0,"issues_closed_count":3,"pull_requests_closed_count":1,"pull_request_authors_count":1,"issue_authors_count":2,"avg_comments_per_issue":0.2,"avg_comments_per_pull_request":0.0,"merged_pull_requests_count":1,"bot_issues_count":0,"bot_pull_requests_count":0,"past_year_issues_count":0,"past_year_pull_requests_count":0,"past_year_avg_time_to_close_issue":null,"past_year_avg_time_to_close_pull_request":null,"past_year_issues_closed_count":0,"past_year_pull_requests_closed_count":0,"past_year_pull_request_authors_count":0,"past_year_issue_authors_count":0,"past_year_avg_comments_per_issue":null,"past_year_avg_comments_per_pull_request":null,"past_year_bot_issues_count":0,"past_year_bot_pull_requests_count":0,"past_year_merged_pull_requests_count":0,"created_at":"2023-05-15T20:20:56.643Z","updated_at":"2025-06-24T01:52:15.692Z","repository_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA","issues_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories/CSBiology%2FTMEA/issues","issue_labels_count":{},"pull_request_labels_count":{},"issue_author_associations_count":{"MEMBER":10},"pull_request_author_associations_count":{"MEMBER":2},"issue_authors":{"kMutagene":8,"bvenn":2},"pull_request_authors":{"bvenn":2},"host":{"name":"GitHub","url":"https://github.com","kind":"github","last_synced_at":"2025-08-31T00:00:11.523Z","repositories_count":8447538,"issues_count":20889155,"pull_requests_count":52982947,"authors_count":8091196,"icon_url":"https://github.com/github.png","host_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories","owners_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/owners","authors_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors"},"past_year_issue_labels_count":{},"past_year_pull_request_labels_count":{},"past_year_issue_author_associations_count":{},"past_year_pull_request_author_associations_count":{},"past_year_issue_authors":{},"past_year_pull_request_authors":{},"maintainers":[{"login":"kMutagene","count":8,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/kMutagene"},{"login":"bvenn","count":4,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/bvenn"}],"active_maintainers":[]},"events":{"total":{},"last_year":{}},"keywords":["bioinformatics","biostatistics","deedle","enrichment-score","f-sharp","genes","gsea","plotly"],"dependencies":null,"score":null,"created_at":"2025-09-09T03:28:53.706Z","updated_at":"2025-10-07T08:43:07.541Z","avatar_url":"https://github.com/CSBiology.png","language":"F#","category":null,"sub_category":null,"monthly_downloads":0,"funding_links":[],"readme_doi_urls":["https://doi.org/10.3390/e22091030"],"works":{},"citation_counts":{},"total_citations":0,"keywords_from_contributors":[],"project_url":"https://science.ecosyste.ms/api/v1/projects/197455","html_url":"https://science.ecosyste.ms/projects/197455"}