{"id":61794,"name":"dominoSignal","description":"A software package for connecting cell level features in single cell RNA sequencing data with receptor ligand activity.","url":"https://github.com/fertiglab/dominosignal","last_synced_at":"2025-09-08T12:33:26.966Z","repository":{"id":146065754,"uuid":"613331081","full_name":"FertigLab/dominoSignal","owner":"FertigLab","description":"A software package for connecting cell level features in single cell RNA sequencing data with receptor ligand activity.","archived":false,"fork":true,"pushed_at":"2025-02-10T14:40:11.000Z","size":102162,"stargazers_count":6,"open_issues_count":9,"forks_count":4,"subscribers_count":1,"default_branch":"master","last_synced_at":"2025-08-27T06:48:30.925Z","etag":null,"topics":[],"latest_commit_sha":null,"homepage":"https://fertiglab.github.io/dominoSignal/","language":"R","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":"Elisseeff-Lab/domino","license":"gpl-3.0","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/FertigLab.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":"LICENSE","code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null}},"created_at":"2023-03-13T11:14:07.000Z","updated_at":"2025-08-19T06:30:25.000Z","dependencies_parsed_at":"2023-09-27T02:09:53.577Z","dependency_job_id":"f5b3918f-7648-4a79-bb64-dffe6edce6fa","html_url":"https://github.com/FertigLab/dominoSignal","commit_stats":null,"previous_names":["fertiglab/dominosignal"],"tags_count":0,"template":false,"template_full_name":null,"purl":"pkg:github/FertigLab/dominoSignal","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/FertigLab","download_url":"https://codeload.github.com/FertigLab/dominoSignal/tar.gz/refs/heads/master","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal/sbom","scorecard":null,"host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":274174106,"owners_count":25235202,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","status":"online","status_checked_at":"2025-09-08T02:00:09.813Z","response_time":121,"last_error":null,"robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":true,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"owner":{"login":"FertigLab","name":"FertigLab","uuid":"16355285","kind":"organization","description":"Software projects in computational biology and bioinformatics in Elana Fertig's lab in Oncology Biostatistics and Bioinformatics at JHMI","email":"ejfertig@jhmi.edu","website":null,"location":null,"twitter":null,"company":null,"icon_url":"https://avatars.githubusercontent.com/u/16355285?v=4","repositories_count":68,"last_synced_at":"2024-03-26T11:16:11.794Z","metadata":{"has_sponsors_listing":false},"html_url":"https://github.com/FertigLab","funding_links":[],"total_stars":103,"followers":18,"following":0,"created_at":"2022-11-03T17:21:44.065Z","updated_at":"2024-03-26T11:16:14.062Z","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/FertigLab","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/FertigLab/repositories"},"packages":[{"id":11011498,"name":"dominoSignal","ecosystem":"bioconductor","description":"Cell Communication Analysis for Single Cell RNA Sequencing","homepage":"https://fertiglab.github.io/dominoSignal/ ","licenses":"GPL-3 | file LICENSE","normalized_licenses":["AML"],"repository_url":"https://github.com/fertiglab/dominoSignal","keywords_array":["Network","SingleCell","Software","SystemsBiology","Transcriptomics"],"namespace":null,"versions_count":2,"first_release_published_at":"2024-11-01T08:59:38.541Z","latest_release_published_at":"2025-05-18T00:02:22.519Z","latest_release_number":"1.2.0","last_synced_at":"2025-08-26T23:35:02.673Z","created_at":"2024-11-01T08:59:37.918Z","updated_at":"2025-08-27T14:34:00.710Z","registry_url":"https://bioconductor.org/packages/dominoSignal","install_command":null,"documentation_url":"https://bioconductor.org/packages/release/bioc/vignettes/dominoSignal/inst/doc/dominoSignal.pdf","metadata":{},"repo_metadata":{"id":146065754,"uuid":"613331081","full_name":"FertigLab/dominoSignal","owner":"FertigLab","description":"A software package for connecting cell level features in single cell RNA sequencing data with receptor ligand activity.","archived":false,"fork":true,"pushed_at":"2025-02-10T14:40:11.000Z","size":102162,"stargazers_count":6,"open_issues_count":9,"forks_count":4,"subscribers_count":1,"default_branch":"master","last_synced_at":"2025-08-27T06:48:30.925Z","etag":null,"topics":[],"latest_commit_sha":null,"homepage":"https://fertiglab.github.io/dominoSignal/","language":"R","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":"Elisseeff-Lab/domino","license":"gpl-3.0","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/FertigLab.png","metadata":{"files":{"readme":"README.md","changelog":null,"contributing":null,"funding":null,"license":"LICENSE","code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null}},"created_at":"2023-03-13T11:14:07.000Z","updated_at":"2025-08-19T06:30:25.000Z","dependencies_parsed_at":"2023-09-27T02:09:53.577Z","dependency_job_id":"f5b3918f-7648-4a79-bb64-dffe6edce6fa","html_url":"https://github.com/FertigLab/dominoSignal","commit_stats":null,"previous_names":["fertiglab/dominosignal"],"tags_count":0,"template":false,"template_full_name":null,"purl":"pkg:github/FertigLab/dominoSignal","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/FertigLab","download_url":"https://codeload.github.com/FertigLab/dominoSignal/tar.gz/refs/heads/master","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal/sbom","scorecard":null,"host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":272341125,"owners_count":24917492,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","status":"online","status_checked_at":"2025-08-27T02:00:09.397Z","response_time":76,"last_error":null,"robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":true,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"},"owner_record":{"login":"FertigLab","name":"FertigLab","uuid":"16355285","kind":"organization","description":"Software projects in computational biology and bioinformatics in Elana Fertig's lab in Oncology Biostatistics and Bioinformatics at JHMI","email":"ejfertig@jhmi.edu","website":null,"location":null,"twitter":null,"company":null,"icon_url":"https://avatars.githubusercontent.com/u/16355285?v=4","repositories_count":68,"last_synced_at":"2024-03-26T11:16:11.794Z","metadata":{"has_sponsors_listing":false},"html_url":"https://github.com/FertigLab","funding_links":[],"total_stars":103,"followers":18,"following":0,"created_at":"2022-11-03T17:21:44.065Z","updated_at":"2024-03-26T11:16:14.062Z","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/FertigLab","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/FertigLab/repositories"},"tags":[]},"repo_metadata_updated_at":"2025-08-27T14:34:00.710Z","dependent_packages_count":0,"downloads":2252,"downloads_period":"total","dependent_repos_count":0,"rankings":{"downloads":95.56103575832306,"dependent_repos_count":0.0,"dependent_packages_count":31.483764899301274,"stargazers_count":null,"forks_count":null,"docker_downloads_count":null,"average":42.34826688587478},"purl":"pkg:bioconductor/dominoSignal","advisories":[],"docker_usage_url":"https://docker.ecosyste.ms/usage/bioconductor/dominoSignal","docker_dependents_count":null,"docker_downloads_count":null,"usage_url":"https://repos.ecosyste.ms/usage/bioconductor/dominoSignal","dependent_repositories_url":"https://repos.ecosyste.ms/api/v1/usage/bioconductor/dominoSignal/dependencies","status":null,"funding_links":[],"critical":null,"issue_metadata":null,"versions_url":"https://packages.ecosyste.ms/api/v1/registries/bioconductor.org/packages/dominoSignal/versions","version_numbers_url":"https://packages.ecosyste.ms/api/v1/registries/bioconductor.org/packages/dominoSignal/version_numbers","dependent_packages_url":"https://packages.ecosyste.ms/api/v1/registries/bioconductor.org/packages/dominoSignal/dependent_packages","related_packages_url":"https://packages.ecosyste.ms/api/v1/registries/bioconductor.org/packages/dominoSignal/related_packages","maintainers":[{"uuid":"jmitch81@jhmi.edu","login":null,"name":"Jacob T Mitchell","email":"jmitch81@jhmi.edu","url":null,"packages_count":1,"html_url":null,"role":null,"created_at":"2024-11-01T09:10:30.075Z","updated_at":"2024-11-01T09:10:30.075Z","packages_url":"https://packages.ecosyste.ms/api/v1/registries/bioconductor.org/maintainers/jmitch81@jhmi.edu/packages"}],"registry":{"name":"bioconductor.org","url":"https://bioconductor.org","ecosystem":"bioconductor","default":true,"packages_count":2505,"maintainers_count":3164,"namespaces_count":0,"keywords_count":1086,"github":"Bioconductor","metadata":{"funded_packages_count":3},"icon_url":"https://github.com/Bioconductor.png","created_at":"2023-10-12T14:09:56.428Z","updated_at":"2025-09-08T06:51:28.460Z","packages_url":"https://packages.ecosyste.ms/api/v1/registries/bioconductor.org/packages","maintainers_url":"https://packages.ecosyste.ms/api/v1/registries/bioconductor.org/maintainers","namespaces_url":"https://packages.ecosyste.ms/api/v1/registries/bioconductor.org/namespaces"}}],"commits":{"id":11003339,"full_name":"fertiglab/dominosignal","default_branch":"master","committers":[{"name":"Jacob Mitchell","email":"jmitch81@jhmi.edu","login":null,"count":288},{"name":"dimalvovs","email":"dmitrijs.lvovs@gmail.com","login":null,"count":81},{"name":"kjkrishnan","email":"kkrish12@jhmi.edu","login":null,"count":78},{"name":"dimalvovs","email":"dlvovs1@jh.edu","login":null,"count":27},{"name":"Chris-Cherry","email":"ccherry.6574@gmail.com","login":null,"count":18},{"name":"Chris-Cherry","email":"38076553+Chris-Cherry@users.noreply.github.com","login":null,"count":11},{"name":"jmitchell81","email":"jmitchell81@users.noreply.github.com","login":null,"count":10},{"name":"kjkrishnan","email":"60410113+kjkrishnan@users.noreply.github.com","login":null,"count":7},{"name":"Jacob Mitchell","email":"87323483+jmitchell81@users.noreply.github.com","login":null,"count":5},{"name":"kjkrishnan","email":"kjkrishnan@users.noreply.github.com","login":null,"count":5},{"name":"Sushma Nagaraj","email":"sushmanagaraj@eb-gi-h3nlmd6m.win.ad.jhu.edu","login":null,"count":3},{"name":"Sushma Nagaraj","email":"sushmanagaraj@eb-gi-h3nlmd6m.myfiosgateway.com","login":null,"count":2},{"name":"dimalvovs","email":"dimalvovs@users.noreply.github.com","login":null,"count":2},{"name":"theron-palmer","email":"theropalm@gmail.com","login":null,"count":2},{"name":"GitHub Action","email":"action@github.com","login":null,"count":1},{"name":"J Wokaty","email":"jennifer.wokaty@sph.cuny.edu","login":null,"count":1},{"name":"Sushma Nagaraj","email":"sushmanagaraj@EB-ONC-H3NLMD6M.local","login":null,"count":1},{"name":"snagara5","email":"snagara5@EB-GI-MLYDYQHR25.local","login":null,"count":1}],"total_commits":543,"total_committers":18,"total_bot_commits":0,"total_bot_committers":0,"mean_commits":30.166666666666668,"dds":0.4696132596685083,"past_year_committers":[{"name":"Jacob Mitchell","email":"jmitch81@jhmi.edu","login":null,"count":45},{"name":"jmitchell81","email":"jmitchell81@users.noreply.github.com","login":null,"count":3},{"name":"kjkrishnan","email":"kkrish12@jhmi.edu","login":null,"count":2},{"name":"J Wokaty","email":"jennifer.wokaty@sph.cuny.edu","login":null,"count":1},{"name":"Sushma Nagaraj","email":"sushmanagaraj@EB-ONC-H3NLMD6M.local","login":null,"count":1},{"name":"dimalvovs","email":"dmitrijs.lvovs@gmail.com","login":null,"count":1},{"name":"kjkrishnan","email":"kjkrishnan@users.noreply.github.com","login":null,"count":1},{"name":"snagara5","email":"snagara5@EB-GI-MLYDYQHR25.local","login":null,"count":1}],"past_year_total_commits":55,"past_year_total_committers":8,"past_year_total_bot_commits":0,"past_year_total_bot_committers":0,"past_year_mean_commits":6.875,"past_year_dds":0.18181818181818177,"last_synced_at":"2025-09-08T10:58:36.208Z","last_synced_commit":"35445dc8683eaabdefdbde44de0a7f90b1526357","created_at":"2025-09-08T10:54:50.029Z","updated_at":"2025-09-08T10:58:33.511Z","commits_url":"https://commits.ecosyste.ms/api/v1/hosts/GitHub/repositories/fertiglab%2Fdominosignal/commits","host":{"name":"GitHub","url":"https://github.com","kind":"github","last_synced_at":"2025-09-08T00:00:16.827Z","repositories_count":5483322,"commits_count":854270774,"contributors_count":31138750,"owners_count":908526,"icon_url":"https://github.com/github.png","host_url":"https://commits.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://commits.ecosyste.ms/api/v1/hosts/GitHub/repositories"}},"issues_stats":{"full_name":"FertigLab/dominoSignal","html_url":"https://github.com/FertigLab/dominoSignal","last_synced_at":"2025-08-31T07:55:55.954Z","status":null,"issues_count":3,"pull_requests_count":3,"avg_time_to_close_issue":2076571.0,"avg_time_to_close_pull_request":86789.5,"issues_closed_count":1,"pull_requests_closed_count":2,"pull_request_authors_count":2,"issue_authors_count":2,"avg_comments_per_issue":0.0,"avg_comments_per_pull_request":0.0,"merged_pull_requests_count":2,"bot_issues_count":0,"bot_pull_requests_count":0,"past_year_issues_count":3,"past_year_pull_requests_count":3,"past_year_avg_time_to_close_issue":2076571.0,"past_year_avg_time_to_close_pull_request":86789.5,"past_year_issues_closed_count":1,"past_year_pull_requests_closed_count":2,"past_year_pull_request_authors_count":2,"past_year_issue_authors_count":2,"past_year_avg_comments_per_issue":0.0,"past_year_avg_comments_per_pull_request":0.0,"past_year_bot_issues_count":0,"past_year_bot_pull_requests_count":0,"past_year_merged_pull_requests_count":2,"created_at":"2025-08-30T10:44:55.046Z","updated_at":"2025-09-03T04:29:02.887Z","repository_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal","issues_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories/FertigLab%2FdominoSignal/issues","issue_labels_count":{},"pull_request_labels_count":{"bug":1},"issue_author_associations_count":{"COLLABORATOR":19,"NONE":2},"pull_request_author_associations_count":{"COLLABORATOR":26},"issue_authors":{"dimalvovs":9,"jmitchell81":6,"kjkrishnan":4,"bryan-mccarty":1,"mindykimgraham":1},"pull_request_authors":{"jmitchell81":14,"kjkrishnan":6,"dimalvovs":4,"snag-gh":2},"host":{"name":"GitHub","url":"https://github.com","kind":"github","last_synced_at":"2025-09-08T00:00:17.013Z","repositories_count":10164087,"issues_count":31988492,"pull_requests_count":100218704,"authors_count":10728235,"icon_url":"https://github.com/github.png","host_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories","owners_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/owners","authors_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors"},"past_year_issue_labels_count":{},"past_year_pull_request_labels_count":{"bug":1},"past_year_issue_author_associations_count":{"COLLABORATOR":5,"NONE":2},"past_year_pull_request_author_associations_count":{"COLLABORATOR":10},"past_year_issue_authors":{"dimalvovs":4,"bryan-mccarty":1,"jmitchell81":1,"mindykimgraham":1},"past_year_pull_request_authors":{"jmitchell81":4,"dimalvovs":2,"kjkrishnan":2,"snag-gh":2},"maintainers":[{"login":"jmitchell81","count":20,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/jmitchell81"},{"login":"dimalvovs","count":13,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/dimalvovs"},{"login":"kjkrishnan","count":10,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/kjkrishnan"},{"login":"snag-gh","count":2,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/snag-gh"}],"active_maintainers":[{"login":"dimalvovs","count":6,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/dimalvovs"},{"login":"jmitchell81","count":5,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/jmitchell81"},{"login":"kjkrishnan","count":2,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/kjkrishnan"},{"login":"snag-gh","count":2,"url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors/snag-gh"}]},"events":{"total":{"CreateEvent":11,"ReleaseEvent":1,"IssuesEvent":16,"WatchEvent":2,"DeleteEvent":4,"IssueCommentEvent":12,"PushEvent":58,"PullRequestReviewEvent":13,"PullRequestReviewCommentEvent":7,"PullRequestEvent":18,"ForkEvent":1},"last_year":{"CreateEvent":11,"ReleaseEvent":1,"IssuesEvent":16,"WatchEvent":2,"DeleteEvent":4,"IssueCommentEvent":12,"PushEvent":58,"PullRequestReviewEvent":13,"PullRequestReviewCommentEvent":7,"PullRequestEvent":18,"ForkEvent":1}},"keywords":[],"dependencies":[{"ecosystem":"cran","filepath":"DESCRIPTION","sha":null,"kind":"manifest","created_at":"2023-09-27T02:09:53.519Z","updated_at":"2023-09-27T02:09:53.519Z","repository_link":"https://github.com/FertigLab/dominoSignal/blob/master/DESCRIPTION","dependencies":[{"id":13963944044,"package_name":"R","ecosystem":"cran","requirements":"\u003e= 3.6.2","direct":true,"kind":"depends","optional":false},{"id":13963944045,"package_name":"biomaRt","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":13963944048,"package_name":"igraph","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":13963944046,"package_name":"plyr","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":13963944047,"package_name":"dplyr","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":13963944049,"package_name":"circlize","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":13963944050,"package_name":"ComplexHeatmap","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false}]}],"score":13.318439899430619,"created_at":"2025-09-08T10:46:39.990Z","updated_at":"2025-10-07T08:24:11.642Z","avatar_url":"https://github.com/FertigLab.png","language":"R","category":null,"sub_category":null,"monthly_downloads":0,"funding_links":[],"readme_doi_urls":["https://doi.org/10.1038/s41551-021-00770-5"],"works":{},"citation_counts":{},"total_citations":0,"keywords_from_contributors":["ontology"],"project_url":"https://science.ecosyste.ms/api/v1/projects/61794","html_url":"https://science.ecosyste.ms/projects/61794"}