{"id":74361,"name":"pkpdsim","description":"Simulate PK-PD models defined as ODE systems","url":"https://github.com/insightrx/pkpdsim","last_synced_at":"2025-09-08T16:18:39.815Z","repository":{"id":24068789,"uuid":"100528653","full_name":"InsightRX/PKPDsim","owner":"InsightRX","description":"Simulate PK-PD models defined as ODE systems","archived":false,"fork":false,"pushed_at":"2025-09-05T19:34:23.000Z","size":45896,"stargazers_count":42,"open_issues_count":0,"forks_count":15,"subscribers_count":11,"default_branch":"master","last_synced_at":"2025-09-05T19:36:45.884Z","etag":null,"topics":["ode","pharmacodynamics","pharmacokinetics","pharmacometrics","r"],"latest_commit_sha":null,"homepage":"https://insightrx.github.io/PKPDsim/","language":"R","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":"other","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/InsightRX.png","metadata":{"files":{"readme":"README.md","changelog":"NEWS.md","contributing":null,"funding":null,"license":"LICENSE","code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null,"zenodo":null,"notice":null,"maintainers":null,"copyright":null,"agents":null,"dco":null,"cla":null}},"created_at":"2017-08-16T20:11:43.000Z","updated_at":"2025-09-05T19:25:05.000Z","dependencies_parsed_at":"2023-02-16T21:31:29.921Z","dependency_job_id":"76cb3766-ddca-4b05-94ce-0d6d170501cf","html_url":"https://github.com/InsightRX/PKPDsim","commit_stats":{"total_commits":901,"total_committers":12,"mean_commits":75.08333333333333,"dds":0.5538290788013318,"last_synced_commit":"2f14e1cb3927e0d2813459551d821fe162f61be5"},"previous_names":[],"tags_count":45,"template":false,"template_full_name":null,"purl":"pkg:github/InsightRX/PKPDsim","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/InsightRX","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/refs/heads/master","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/sbom","scorecard":null,"host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":274210605,"owners_count":25241792,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","status":"online","status_checked_at":"2025-09-08T02:00:09.813Z","response_time":121,"last_error":null,"robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":true,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"}},"owner":{"login":"InsightRX","name":"InsightRX","uuid":"14945763","kind":"organization","description":"Precision dosing and clinical analytics","email":"info@insight-rx.com","website":"www.insight-rx.com","location":"San Francisco, CA","twitter":null,"company":null,"icon_url":"https://avatars.githubusercontent.com/u/14945763?v=4","repositories_count":5,"last_synced_at":"2023-02-27T05:15:31.631Z","metadata":{"has_sponsors_listing":false},"html_url":"https://github.com/InsightRX","funding_links":[],"total_stars":null,"followers":null,"following":null,"created_at":"2022-11-10T14:56:03.325Z","updated_at":"2023-02-27T05:15:31.667Z","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/InsightRX","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/InsightRX/repositories"},"packages":[{"id":400442,"name":"PKPDsim","ecosystem":"cran","description":"Tools for Performing Pharmacokinetic-Pharmacodynamic Simulations","homepage":"https://github.com/InsightRX/PKPDsim","licenses":"MIT + file LICENSE","normalized_licenses":["MIT"],"repository_url":"https://github.com/InsightRX/PKPDsim","keywords_array":[],"namespace":null,"versions_count":5,"first_release_published_at":"2022-01-19T09:22:00.000Z","latest_release_published_at":"2025-04-17T00:00:00.000Z","latest_release_number":"1.4.1","last_synced_at":"2025-09-05T19:56:51.954Z","created_at":"2022-04-06T16:57:05.550Z","updated_at":"2025-09-06T15:40:59.345Z","registry_url":"https://cran.r-project.org/package=PKPDsim","install_command":null,"documentation_url":"http://cran.r-project.org/web/packages/PKPDsim/PKPDsim.pdf","metadata":{},"repo_metadata":{"id":24068789,"uuid":"100528653","full_name":"InsightRX/PKPDsim","owner":"InsightRX","description":"Simulate PK-PD models defined as ODE systems","archived":false,"fork":false,"pushed_at":"2025-09-05T19:34:23.000Z","size":45896,"stargazers_count":42,"open_issues_count":0,"forks_count":15,"subscribers_count":11,"default_branch":"master","last_synced_at":"2025-09-05T19:36:45.884Z","etag":null,"topics":["ode","pharmacodynamics","pharmacokinetics","pharmacometrics","r"],"latest_commit_sha":null,"homepage":"https://insightrx.github.io/PKPDsim/","language":"R","has_issues":true,"has_wiki":null,"has_pages":null,"mirror_url":null,"source_name":null,"license":"other","status":null,"scm":"git","pull_requests_enabled":true,"icon_url":"https://github.com/InsightRX.png","metadata":{"files":{"readme":"README.md","changelog":"NEWS.md","contributing":null,"funding":null,"license":"LICENSE","code_of_conduct":null,"threat_model":null,"audit":null,"citation":null,"codeowners":null,"security":null,"support":null,"governance":null,"roadmap":null,"authors":null,"dei":null,"publiccode":null,"codemeta":null,"zenodo":null,"notice":null,"maintainers":null,"copyright":null,"agents":null,"dco":null,"cla":null}},"created_at":"2017-08-16T20:11:43.000Z","updated_at":"2025-09-05T19:25:05.000Z","dependencies_parsed_at":"2023-02-16T21:31:29.921Z","dependency_job_id":"76cb3766-ddca-4b05-94ce-0d6d170501cf","html_url":"https://github.com/InsightRX/PKPDsim","commit_stats":{"total_commits":901,"total_committers":12,"mean_commits":75.08333333333333,"dds":0.5538290788013318,"last_synced_commit":"2f14e1cb3927e0d2813459551d821fe162f61be5"},"previous_names":[],"tags_count":45,"template":false,"template_full_name":null,"purl":"pkg:github/InsightRX/PKPDsim","repository_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim","tags_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags","releases_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/releases","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/manifests","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/InsightRX","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/refs/heads/master","sbom_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/sbom","scorecard":null,"host":{"name":"GitHub","url":"https://github.com","kind":"github","repositories_count":273926571,"owners_count":25192318,"icon_url":"https://github.com/github.png","version":null,"created_at":"2022-05-30T11:31:42.601Z","updated_at":"2022-07-04T15:15:14.044Z","status":"online","status_checked_at":"2025-09-06T02:00:13.247Z","response_time":2576,"last_error":null,"robots_txt_status":"success","robots_txt_updated_at":"2025-07-24T06:49:26.215Z","robots_txt_url":"https://github.com/robots.txt","online":true,"can_crawl_api":true,"host_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories","repository_names_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repository_names","owners_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners"},"owner_record":{"login":"InsightRX","name":"InsightRX","uuid":"14945763","kind":"organization","description":"Precision dosing and clinical analytics","email":"info@insight-rx.com","website":"www.insight-rx.com","location":"San Francisco, CA","twitter":null,"company":null,"icon_url":"https://avatars.githubusercontent.com/u/14945763?v=4","repositories_count":5,"last_synced_at":"2023-02-27T05:15:31.631Z","metadata":{"has_sponsors_listing":false},"html_url":"https://github.com/InsightRX","funding_links":[],"total_stars":null,"followers":null,"following":null,"created_at":"2022-11-10T14:56:03.325Z","updated_at":"2023-02-27T05:15:31.667Z","owner_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/InsightRX","repositories_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/owners/InsightRX/repositories"},"tags":[{"name":"v1.76","sha":"ddc6f66b6c3aedc70489e4f8f75e703ff9c26881","kind":"tag","published_at":"2025-08-28T18:10:28.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.76","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.76","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.76","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.76","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.76/manifests"},{"name":"v1.75","sha":"8c3bbdac80f7121786fe2540569f85736436e162","kind":"tag","published_at":"2025-07-31T15:29:45.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.75","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.75","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.75","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.75","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.75/manifests"},{"name":"v1.74","sha":"7c806555980574607b6f199f3ad0ad603a7fa3b9","kind":"tag","published_at":"2025-07-08T15:23:29.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.74","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.74","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.74","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.74","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.74/manifests"},{"name":"v1.73","sha":"d2888e068cdfa1470761beb30bcc6a8a14c409a0","kind":"tag","published_at":"2025-06-06T14:54:01.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.73","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.73","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.73","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.73","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.73/manifests"},{"name":"v1.72","sha":"639b5b383a3f293eed65a2c749e81449e7a7c72d","kind":"tag","published_at":"2025-05-08T21:59:30.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.72","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.72","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.72","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.72","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.72/manifests"},{"name":"pkpdsim-1.4.1","sha":"18ae7fb31cc26594070935f77f1e5d434053570b","kind":"commit","published_at":"2025-04-21T15:46:20.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/pkpdsim-1.4.1","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/pkpdsim-1.4.1","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@pkpdsim-1.4.1","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/pkpdsim-1.4.1","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/pkpdsim-1.4.1/manifests"},{"name":"v1.71","sha":"ebc56aaa668255d81a7c149e388a71a13cc222f6","kind":"tag","published_at":"2025-04-11T15:23:49.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.71","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.71","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.71","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.71","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.71/manifests"},{"name":"v1.70","sha":"ebc56aaa668255d81a7c149e388a71a13cc222f6","kind":"tag","published_at":"2025-03-13T18:06:14.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.70","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.70","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.70","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.70","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.70/manifests"},{"name":"v1.69","sha":"4fe24fb407233e532a9fe44a89c9483b4503660c","kind":"tag","published_at":"2025-02-14T18:00:12.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.69","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.69","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.69","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.69","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.69/manifests"},{"name":"v1.68","sha":"4fe24fb407233e532a9fe44a89c9483b4503660c","kind":"tag","published_at":"2025-01-16T21:54:05.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.68","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.68","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.68","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.68","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.68/manifests"},{"name":"v1.67","sha":"4fc1720aab92a72a64d4518b893ff1c10a07c6e0","kind":"tag","published_at":"2024-12-13T17:48:35.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.67","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.67","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.67","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.67","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.67/manifests"},{"name":"v1.66","sha":"4fc1720aab92a72a64d4518b893ff1c10a07c6e0","kind":"tag","published_at":"2024-11-20T17:24:26.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.66","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.66","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.66","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.66","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.66/manifests"},{"name":"v1.65","sha":"458c026d81962e6ed0c30bc4da4625a9823d0fc1","kind":"tag","published_at":"2024-10-16T16:55:18.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.65","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.65","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.65","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.65","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.65/manifests"},{"name":"v1.64","sha":"458c026d81962e6ed0c30bc4da4625a9823d0fc1","kind":"tag","published_at":"2024-09-06T15:17:02.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.64","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.64","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.64","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.64","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.64/manifests"},{"name":"v1.63","sha":"079dbd214168cb2a224ba221547486b85ca56a6a","kind":"tag","published_at":"2024-08-07T16:34:42.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.63","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.63","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.63","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.63","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.63/manifests"},{"name":"v1.62","sha":"91ad16389bea8c1bf6dc626903456af9e660bfe0","kind":"tag","published_at":"2024-07-12T16:01:12.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.62","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.62","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.62","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.62","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.62/manifests"},{"name":"v1.61","sha":"9dcb9a4138544c4bd6acf642f233f5b098254f3a","kind":"tag","published_at":"2024-06-06T20:43:47.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.61","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.61","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.61","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.61","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.61/manifests"},{"name":"v1.60","sha":"9dcb9a4138544c4bd6acf642f233f5b098254f3a","kind":"tag","published_at":"2024-05-06T14:47:36.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.60","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.60","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.60","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.60","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.60/manifests"},{"name":"v1.59.0","sha":"60583a09e2f4e73b64d0c06ac7aba6c56345304e","kind":"commit","published_at":"2024-04-03T18:43:48.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.59.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.59.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.59.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.59.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.59.0/manifests"},{"name":"v1.58.0","sha":"e75a93ef4aa6acad13695e0030b1b608876cb8ca","kind":"commit","published_at":"2024-03-07T21:17:10.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.58.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.58.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.58.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.58.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.58.0/manifests"},{"name":"v1.56.0","sha":"d1b7e6af8811e9541ba2a4088e3d7e1f60d44566","kind":"commit","published_at":"2024-01-12T18:17:08.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.56.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.56.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.56.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.56.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.56.0/manifests"},{"name":"v1.57.0","sha":"d1b7e6af8811e9541ba2a4088e3d7e1f60d44566","kind":"commit","published_at":"2024-01-12T18:17:08.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.57.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.57.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.57.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.57.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.57.0/manifests"},{"name":"v1.55.0","sha":"3d214c97d0c6dc2fc535d573c27cb076e878447b","kind":"commit","published_at":"2023-10-31T18:24:24.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.55.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.55.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.55.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.55.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.55.0/manifests"},{"name":"v1.54.0","sha":"3d214c97d0c6dc2fc535d573c27cb076e878447b","kind":"commit","published_at":"2023-10-31T18:24:24.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.54.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.54.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.54.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.54.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.54.0/manifests"},{"name":"v1.53.0","sha":"5bbc5d686df09e46bc53d40c4bc933eed5f66d90","kind":"commit","published_at":"2023-09-26T22:38:50.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.53.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.53.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.53.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.53.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.53.0/manifests"},{"name":"v1.52.0","sha":"3b63d11305c78da66b6996bb85a7fa5f684f3cbf","kind":"commit","published_at":"2023-06-26T22:06:49.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.52.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.52.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.52.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.52.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.52.0/manifests"},{"name":"v1.51.0","sha":"3b63d11305c78da66b6996bb85a7fa5f684f3cbf","kind":"commit","published_at":"2023-06-26T22:06:49.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.51.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.51.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.51.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.51.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.51.0/manifests"},{"name":"v1.50.0","sha":"91eb936f4cac304ba1252114c410e33ef4fa75fa","kind":"commit","published_at":"2023-05-18T06:15:52.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.50.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.50.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.50.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.50.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.50.0/manifests"},{"name":"v1.47.0","sha":"098257f1354bfc33de00f66bba2d7a7cbd898de9","kind":"commit","published_at":"2023-03-06T19:53:46.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.47.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.47.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.47.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.47.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.47.0/manifests"},{"name":"v1.48.0","sha":"098257f1354bfc33de00f66bba2d7a7cbd898de9","kind":"commit","published_at":"2023-03-06T19:53:46.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.48.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.48.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.48.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.48.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.48.0/manifests"},{"name":"v1.49.0","sha":"098257f1354bfc33de00f66bba2d7a7cbd898de9","kind":"commit","published_at":"2023-03-06T19:53:46.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.49.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.49.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.49.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.49.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.49.0/manifests"},{"name":"v1.45.0","sha":"5f749c4fbaa677ad4c0dc90412fbd6d48d20a4a0","kind":"commit","published_at":"2022-11-30T20:51:04.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.45.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.45.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.45.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.45.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.45.0/manifests"},{"name":"v1.46.0","sha":"5f749c4fbaa677ad4c0dc90412fbd6d48d20a4a0","kind":"commit","published_at":"2022-11-30T20:51:04.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.46.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.46.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.46.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.46.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.46.0/manifests"},{"name":"v1.43.0","sha":"7883cf2803c3fd47c4849071d31497da19177201","kind":"commit","published_at":"2022-10-13T21:20:04.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.43.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.43.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.43.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.43.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.43.0/manifests"},{"name":"v1.44.0","sha":"7883cf2803c3fd47c4849071d31497da19177201","kind":"commit","published_at":"2022-10-13T21:20:04.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.44.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.44.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.44.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.44.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.44.0/manifests"},{"name":"v1.41.0","sha":"acffc2cf150e5bce97e618a4fec9fb163895f802","kind":"commit","published_at":"2022-07-11T18:54:33.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.41.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.41.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.41.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.41.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.41.0/manifests"},{"name":"v1.42.0","sha":"acffc2cf150e5bce97e618a4fec9fb163895f802","kind":"commit","published_at":"2022-07-11T18:54:33.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.42.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.42.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.42.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.42.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.42.0/manifests"},{"name":"v1.40.0","sha":"03b393e188daa48a91e790d5a82ef8ed3ecc2aab","kind":"commit","published_at":"2022-07-05T21:14:52.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.40.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.40.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.40.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.40.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.40.0/manifests"},{"name":"v1.39.2","sha":"e0516e49647fe116d31de653c1fedd277aabca04","kind":"tag","published_at":"2022-06-20T20:25:23.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.39.2","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.39.2","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.39.2","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.39.2","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.39.2/manifests"},{"name":"v1.39.1","sha":"50a72b35343b276f6f08681a7e16e239442778c2","kind":"commit","published_at":"2022-06-01T23:21:10.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.39.1","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.39.1","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.39.1","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.39.1","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.39.1/manifests"},{"name":"v1.39.0","sha":"8b0126658da30f7e0d67490361bf25e307631d2c","kind":"commit","published_at":"2022-02-04T17:44:57.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.39.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.39.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.39.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.39.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.39.0/manifests"},{"name":"v1.38.0","sha":"b2cc572ee72cb3b359df7373187d47cf3c889253","kind":"commit","published_at":"2022-01-18T19:17:23.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.38.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.38.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.38.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.38.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.38.0/manifests"},{"name":"v1.35.0","sha":"d3a5a254105ab1c5034d994299ba14465c74897c","kind":"commit","published_at":"2021-05-24T23:29:05.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.35.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.35.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.35.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.35.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.35.0/manifests"},{"name":"v1.37.0","sha":"d3a5a254105ab1c5034d994299ba14465c74897c","kind":"commit","published_at":"2021-05-24T23:29:05.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.37.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.37.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.37.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.37.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.37.0/manifests"},{"name":"v1.36.0","sha":"d3a5a254105ab1c5034d994299ba14465c74897c","kind":"commit","published_at":"2021-05-24T23:29:05.000Z","download_url":"https://codeload.github.com/InsightRX/PKPDsim/tar.gz/v1.36.0","html_url":"https://github.com/InsightRX/PKPDsim/releases/tag/v1.36.0","dependencies_parsed_at":null,"dependency_job_id":null,"purl":"pkg:github/InsightRX/PKPDsim@v1.36.0","tag_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.36.0","manifests_url":"https://repos.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/tags/v1.36.0/manifests"}]},"repo_metadata_updated_at":"2025-09-06T15:40:59.344Z","dependent_packages_count":0,"downloads":719,"downloads_period":"last-month","dependent_repos_count":1,"rankings":{"downloads":18.806767586821017,"dependent_repos_count":23.9812959251837,"dependent_packages_count":28.750835003340015,"stargazers_count":10.151380231522706,"forks_count":6.834372217275156,"docker_downloads_count":null,"average":17.70493019282852},"purl":"pkg:cran/PKPDsim","advisories":[],"docker_usage_url":"https://docker.ecosyste.ms/usage/cran/PKPDsim","docker_dependents_count":null,"docker_downloads_count":null,"usage_url":"https://repos.ecosyste.ms/usage/cran/PKPDsim","dependent_repositories_url":"https://repos.ecosyste.ms/api/v1/usage/cran/PKPDsim/dependencies","status":null,"funding_links":[],"critical":null,"issue_metadata":{"last_synced_at":"2025-08-31T18:40:26.463Z","issues_count":15,"pull_requests_count":115,"avg_time_to_close_issue":143029828.33333334,"avg_time_to_close_pull_request":922735.2053571428,"issues_closed_count":15,"pull_requests_closed_count":112,"pull_request_authors_count":9,"issue_authors_count":12,"avg_comments_per_issue":1.0,"avg_comments_per_pull_request":0.4608695652173913,"merged_pull_requests_count":100,"bot_issues_count":0,"bot_pull_requests_count":0,"past_year_issues_count":0,"past_year_pull_requests_count":25,"past_year_avg_time_to_close_issue":null,"past_year_avg_time_to_close_pull_request":838472.6363636364,"past_year_issues_closed_count":0,"past_year_pull_requests_closed_count":22,"past_year_pull_request_authors_count":4,"past_year_issue_authors_count":0,"past_year_avg_comments_per_issue":null,"past_year_avg_comments_per_pull_request":0.2,"past_year_bot_issues_count":0,"past_year_bot_pull_requests_count":0,"past_year_merged_pull_requests_count":17,"issues_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/issues","maintainers":[],"active_maintainers":[]},"versions_url":"https://packages.ecosyste.ms/api/v1/registries/cran.r-project.org/packages/PKPDsim/versions","version_numbers_url":"https://packages.ecosyste.ms/api/v1/registries/cran.r-project.org/packages/PKPDsim/version_numbers","dependent_packages_url":"https://packages.ecosyste.ms/api/v1/registries/cran.r-project.org/packages/PKPDsim/dependent_packages","related_packages_url":"https://packages.ecosyste.ms/api/v1/registries/cran.r-project.org/packages/PKPDsim/related_packages","maintainers":[{"uuid":"ron@insight-rx.com","login":null,"name":"Ron Keizer","email":"ron@insight-rx.com","url":null,"packages_count":2,"html_url":null,"role":null,"created_at":"2022-11-14T17:14:44.962Z","updated_at":"2022-11-14T17:14:44.962Z","packages_url":"https://packages.ecosyste.ms/api/v1/registries/cran.r-project.org/maintainers/ron@insight-rx.com/packages"}],"registry":{"name":"cran.r-project.org","url":"https://cran.r-project.org","ecosystem":"cran","default":true,"packages_count":26181,"maintainers_count":14299,"namespaces_count":0,"keywords_count":8326,"github":"r-project-org","metadata":{"funded_packages_count":539},"icon_url":"https://github.com/r-project-org.png","created_at":"2022-04-06T16:32:25.637Z","updated_at":"2025-09-08T06:54:01.855Z","packages_url":"https://packages.ecosyste.ms/api/v1/registries/cran.r-project.org/packages","maintainers_url":"https://packages.ecosyste.ms/api/v1/registries/cran.r-project.org/maintainers","namespaces_url":"https://packages.ecosyste.ms/api/v1/registries/cran.r-project.org/namespaces"}}],"commits":{"id":720001,"full_name":"InsightRX/PKPDsim","default_branch":"master","committers":[{"name":"ronkeizer","email":"ronkeizer@gmail.com","login":"ronkeizer","count":402},{"name":"Ron Keizer","email":"ron@insight-rx.com","login":"roninsightrx","count":320},{"name":"Kara Woo","email":"kara@insight-rx.com","login":"karawoo","count":129},{"name":"jasmineirx","email":"jasmine@insight-rx.com","login":"jasmineirx","count":96},{"name":"Vikram Matange","email":"vikram@insight-rx.com","login":"vikrammatange","count":32},{"name":"Jordan Brooks","email":"jordan.brooks@insight-rx.com","login":"JordanBrooks33","count":10},{"name":"Devin Pastoor","email":"devin.pastoor@gmail.com","login":"dpastoor","count":4},{"name":"William Fox","email":"wfox413@gmail.com","login":"WillFox","count":3},{"name":"Sermet Pekin","email":"sermet.pekin@gmail.com","login":"SermetPekin","count":2},{"name":"Michael McCarthy","email":"51542091+mccarthy-m-g","login":"mccarthy-m-g","count":2},{"name":"Sungpil Han CPT","email":"shan@acp.kr","login":"shanmdphd","count":1},{"name":"Benjamin Rich","email":"mail@benjaminrich.net","login":"benjaminrich","count":1},{"name":"Dominic Tong","email":"dominic@insight-rx.com@ip-172-31-3-247.us-west-1.compute.internal","login":null,"count":1}],"total_commits":1003,"total_committers":13,"total_bot_commits":0,"total_bot_committers":0,"mean_commits":77.15384615384616,"dds":0.5992023928215353,"past_year_committers":[{"name":"Ron Keizer","email":"ron@insight-rx.com","login":"roninsightrx","count":28},{"name":"jasmineirx","email":"jasmine@insight-rx.com","login":"jasmineirx","count":12},{"name":"Jordan Brooks","email":"jordan.brooks@insight-rx.com","login":"JordanBrooks33","count":10},{"name":"Sermet Pekin","email":"sermet.pekin@gmail.com","login":"SermetPekin","count":2},{"name":"Michael McCarthy","email":"51542091+mccarthy-m-g","login":"mccarthy-m-g","count":2}],"past_year_total_commits":54,"past_year_total_committers":5,"past_year_total_bot_commits":0,"past_year_total_bot_committers":0,"past_year_mean_commits":10.8,"past_year_dds":0.4814814814814815,"last_synced_at":"2025-06-01T23:09:15.344Z","last_synced_commit":"5524d2d2df9f2a314e71605244eb67e895512673","created_at":"2023-03-09T13:01:31.143Z","updated_at":"2025-06-01T23:09:25.223Z","commits_url":"https://commits.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/commits","host":{"name":"GitHub","url":"https://github.com","kind":"github","last_synced_at":"2025-09-02T00:00:07.521Z","repositories_count":5480031,"commits_count":853395369,"contributors_count":31098267,"owners_count":906561,"icon_url":"https://github.com/github.png","host_url":"https://commits.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://commits.ecosyste.ms/api/v1/hosts/GitHub/repositories"}},"issues_stats":{"full_name":"InsightRX/PKPDsim","html_url":"https://github.com/InsightRX/PKPDsim","last_synced_at":"2025-09-07T00:33:01.022Z","status":"active","issues_count":16,"pull_requests_count":138,"avg_time_to_close_issue":134717723.125,"avg_time_to_close_pull_request":1079974.9615384615,"issues_closed_count":16,"pull_requests_closed_count":130,"pull_request_authors_count":9,"issue_authors_count":13,"avg_comments_per_issue":0.9375,"avg_comments_per_pull_request":0.4855072463768116,"merged_pull_requests_count":115,"bot_issues_count":0,"bot_pull_requests_count":0,"past_year_issues_count":0,"past_year_pull_requests_count":27,"past_year_avg_time_to_close_issue":null,"past_year_avg_time_to_close_pull_request":930998.2916666666,"past_year_issues_closed_count":0,"past_year_pull_requests_closed_count":24,"past_year_pull_request_authors_count":4,"past_year_issue_authors_count":0,"past_year_avg_comments_per_issue":null,"past_year_avg_comments_per_pull_request":0.18518518518518517,"past_year_bot_issues_count":0,"past_year_bot_pull_requests_count":0,"past_year_merged_pull_requests_count":18,"created_at":"2023-05-10T22:13:34.840Z","updated_at":"2025-09-07T00:33:01.023Z","repository_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim","issues_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories/InsightRX%2FPKPDsim/issues","issue_labels_count":{},"pull_request_labels_count":{"documentation":2,"bug":1},"issue_author_associations_count":{"NONE":13,"CONTRIBUTOR":3},"pull_request_author_associations_count":{"CONTRIBUTOR":134,"NONE":4},"issue_authors":{"thomasjsln":2,"melmelie":2,"ronkeizer":2,"roninsightrx":1,"lostinpkpd":1,"kkradtke":1,"philipdelff":1,"KyleBarrett":1,"kenujen":1,"e-molitor":1,"jeslo328":1,"cohendnli":1,"zcutts":1},"pull_request_authors":{"roninsightrx":67,"karawoo":29,"jasmineirx":28,"JordanBrooks33":4,"mccarthy-m-g":4,"WillFox":2,"SermetPekin":2,"shanmdphd":1,"lemonardo1":1},"host":{"name":"GitHub","url":"https://github.com","kind":"github","last_synced_at":"2025-09-08T00:00:17.013Z","repositories_count":10168351,"issues_count":32015117,"pull_requests_count":100242866,"authors_count":10730290,"icon_url":"https://github.com/github.png","host_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub","repositories_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/repositories","owners_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/owners","authors_url":"https://issues.ecosyste.ms/api/v1/hosts/GitHub/authors"},"past_year_issue_labels_count":{},"past_year_pull_request_labels_count":{"documentation":2,"bug":1},"past_year_issue_author_associations_count":{},"past_year_pull_request_author_associations_count":{"CONTRIBUTOR":26,"NONE":1},"past_year_issue_authors":{},"past_year_pull_request_authors":{"roninsightrx":13,"jasmineirx":10,"mccarthy-m-g":3,"lemonardo1":1},"maintainers":[],"active_maintainers":[]},"events":{"total":{"CreateEvent":24,"ReleaseEvent":1,"IssuesEvent":15,"WatchEvent":9,"DeleteEvent":8,"IssueCommentEvent":10,"PushEvent":48,"PullRequestReviewCommentEvent":23,"PullRequestEvent":26,"PullRequestReviewEvent":34},"last_year":{"CreateEvent":24,"ReleaseEvent":1,"IssuesEvent":15,"WatchEvent":9,"DeleteEvent":8,"IssueCommentEvent":10,"PushEvent":48,"PullRequestReviewCommentEvent":23,"PullRequestEvent":26,"PullRequestReviewEvent":34}},"keywords":["ode","pharmacodynamics","pharmacokinetics","pharmacometrics","r"],"dependencies":[{"ecosystem":"cran","filepath":"DESCRIPTION","sha":null,"kind":"manifest","created_at":"2022-07-13T05:50:45.388Z","updated_at":"2022-07-13T05:50:45.388Z","repository_link":"https://github.com/InsightRX/PKPDsim/blob/master/DESCRIPTION","dependencies":[{"id":213535451,"package_name":"R","ecosystem":"cran","requirements":"\u003e= 3.0.2","direct":true,"kind":"depends","optional":false},{"id":213535452,"package_name":"Rcpp","ecosystem":"cran","requirements":"\u003e= 0.12.9","direct":true,"kind":"imports","optional":false},{"id":213535453,"package_name":"BH","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":213535454,"package_name":"data.table","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":213535455,"package_name":"stringr","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":213535456,"package_name":"MASS","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":213535457,"package_name":"randtoolbox","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":213535458,"package_name":"jsonlite","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":213535459,"package_name":"stats","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":213535460,"package_name":"parallel","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":213535461,"package_name":"magrittr","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false},{"id":213535462,"package_name":"httr","ecosystem":"cran","requirements":"*","direct":true,"kind":"suggests","optional":false},{"id":213535463,"package_name":"testthat","ecosystem":"cran","requirements":"\u003e= 3.0.0","direct":true,"kind":"suggests","optional":false},{"id":213535464,"package_name":"mockery","ecosystem":"cran","requirements":"*","direct":true,"kind":"suggests","optional":false},{"id":213535465,"package_name":"knitr","ecosystem":"cran","requirements":"*","direct":true,"kind":"suggests","optional":false},{"id":213535466,"package_name":"rmarkdown","ecosystem":"cran","requirements":"*","direct":true,"kind":"suggests","optional":false}]},{"ecosystem":"cran","filepath":"inst/template/DESCRIPTION","sha":null,"kind":"manifest","created_at":"2022-07-13T05:50:45.618Z","updated_at":"2022-07-13T05:50:45.618Z","repository_link":"https://github.com/InsightRX/PKPDsim/blob/master/inst/template/DESCRIPTION","dependencies":[{"id":213535933,"package_name":"Rcpp","ecosystem":"cran","requirements":"\u003e= 0.11.5","direct":true,"kind":"imports","optional":false},{"id":213535934,"package_name":"BH","ecosystem":"cran","requirements":"*","direct":true,"kind":"imports","optional":false}]},{"ecosystem":"actions","filepath":".github/workflows/pkgdown.yaml","sha":null,"kind":"manifest","created_at":"2023-01-14T00:21:23.471Z","updated_at":"2023-01-14T00:21:23.471Z","repository_link":"https://github.com/InsightRX/PKPDsim/blob/master/.github/workflows/pkgdown.yaml","dependencies":[{"id":6891869316,"package_name":"actions/checkout","ecosystem":"actions","requirements":"v2","direct":true,"kind":"composite","optional":false},{"id":6891869317,"package_name":"r-lib/actions/setup-pandoc","ecosystem":"actions","requirements":"v2","direct":true,"kind":"composite","optional":false},{"id":6891869318,"package_name":"r-lib/actions/setup-r","ecosystem":"actions","requirements":"v2","direct":true,"kind":"composite","optional":false},{"id":6891869319,"package_name":"r-lib/actions/setup-r-dependencies","ecosystem":"actions","requirements":"v2","direct":true,"kind":"composite","optional":false},{"id":6891869320,"package_name":"JamesIves/github-pages-deploy-action","ecosystem":"actions","requirements":"4.1.4","direct":true,"kind":"composite","optional":false}]},{"ecosystem":"docker","filepath":"Dockerfile","sha":null,"kind":"manifest","created_at":"2023-01-14T00:21:23.524Z","updated_at":"2023-01-14T00:21:23.524Z","repository_link":"https://github.com/InsightRX/PKPDsim/blob/master/Dockerfile","dependencies":[{"id":6891869321,"package_name":"579831337053.dkr.ecr.us-west-2.amazonaws.com/irx-r-base","ecosystem":"docker","requirements":"latest","direct":true,"kind":"build","optional":false}]}],"score":12.883258113029854,"created_at":"2025-09-08T11:27:45.058Z","updated_at":"2025-10-07T08:26:53.148Z","avatar_url":"https://github.com/InsightRX.png","language":"R","category":null,"sub_category":null,"monthly_downloads":719,"funding_links":[],"readme_doi_urls":[],"works":{},"citation_counts":{},"total_citations":0,"keywords_from_contributors":["clinical-research"],"project_url":"https://science.ecosyste.ms/api/v1/projects/74361","html_url":"https://science.ecosyste.ms/projects/74361"}