https://github.com/arcascope/glioblastoma_circadian

https://github.com/arcascope/glioblastoma_circadian

Science Score: 26.0%

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  • CITATION.cff file
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  • Scientific vocabulary similarity
    Low similarity (4.4%) to scientific vocabulary
Last synced: 10 months ago · JSON representation

Repository

Basic Info
  • Host: GitHub
  • Owner: Arcascope
  • Language: Python
  • Default Branch: main
  • Size: 2.12 MB
Statistics
  • Stars: 0
  • Watchers: 3
  • Forks: 0
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Created about 1 year ago · Last pushed about 1 year ago
Metadata Files
Readme

README.md

Circadian rhythms in Glioblastoma

Introduction

This is code to accompany the paper "Tracking Daily Variations in Rest-Wake to Guide Personalized Timing of Temozolomide for High-Grade Glioma Patients" for the Journal of Biological Rhythms by Gonzalez-Aponte et al.

The story of that paper is that even when people are highly consistent with taking their pills at a prescribed wall clock time, their biological time can still be (and often is) highly variable. This suggests that tracking personal biological time and not just wall clock time could be valuable for chronomedicine.

How to use this

  • run_preprocessing.py prepares the data for analysis (e.g., sorting out time zones)
  • run_analysis.py runs the circadian model on the data
  • make_all_figures.py calls all the functions needed to make the figures in the paper

Questions? Reach out to the senior authors, Erik Herzog and Olivia Walch.

Owner

  • Name: Arcascope Inc
  • Login: Arcascope
  • Kind: organization

GPS for your body's clock

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