https://github.com/astrazeneca/e2-bioprotac
Bioinformatics data analyses - Taylor J. D. et al., Communications Biology 2024, doi: 10.1038/s42003-024-06803-4
Science Score: 13.0%
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Low similarity (3.4%) to scientific vocabulary
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Bioinformatics data analyses - Taylor J. D. et al., Communications Biology 2024, doi: 10.1038/s42003-024-06803-4
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Created almost 3 years ago
· Last pushed almost 2 years ago
https://github.com/AstraZeneca/e2-bioprotac/blob/master/
 Bioinformatics data analysis code accompanying: Taylor, J.D., Barrett, N., Martinez Cuesta, S. et al. Targeted protein degradation using chimeric human E2 ubiquitin-conjugating enzymes. Commun Biol 7, 1179 (2024). https://doi.org/10.1038/s42003-024-06803-4 Software requirements: - R 3.6.0 with libraries: - devtools 2.3.2 - tidyverse 1.3.0 - yaml 2.2.1 - data.table 1.13.2 - limma 3.42.2 - ggplot2 3.3.2 - ggrepel 0.9.1 - VennDiagram 1.6.20 - (data preparation prior to differential expression analysis was performed using an in-house code) To reproduce the data analyses, figures and tables in the paper, install the software requirements and run [code.md](code.md)
Owner
- Name: AstraZeneca
- Login: AstraZeneca
- Kind: organization
- Location: Global
- Website: https://www.astrazeneca.com/
- Repositories: 33
- Profile: https://github.com/AstraZeneca
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