https://github.com/avallecam/hemogr

Analysis code for the manuscript "Hematological profiles in patients infected with malaria in an endemic area of ​​Peru"

https://github.com/avallecam/hemogr

Science Score: 23.0%

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    Found 3 DOI reference(s) in README
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    Low similarity (7.3%) to scientific vocabulary

Keywords

gee longitudinal-data malaria r
Last synced: 5 months ago · JSON representation

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Analysis code for the manuscript "Hematological profiles in patients infected with malaria in an endemic area of ​​Peru"

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gee longitudinal-data malaria r
Created about 6 years ago · Last pushed over 3 years ago
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Readme

README.md

haematological profile of malaria patients

DOI

project structure

  • hemo_db.R -> import and cleaning
  • hemo_bygroup.R -> cross-sectional analysis using baseline data
  • hemo_byvisit.R -> longitudinal analysis using folow-ups!

método: analisis longitudinal

  1. definir variable dependiente
  • Var. dependiente = cada una de las mediciones hematológicas
  • Y: gaussian distribution identity link function
  1. definir variables independientes
  • Var. independiente [time-invariant] = infeccion (especie de plasmodium, dicotomica)
  • Var. independiente [confusores] = edad (continua), sexo (dicotómica)
  1. objetivo:
  • test if, in average, the change of Y in time is related with a time-invariant exposure
  • this translates as including an interaction term between Y and the time-invariant exposure (Vittinghoff, 2nd edition, p271)
  1. correlation structure

    • the repeated measurements were taken through time
    • only three time measurements per pacient were included
    • the measurement interval times are not equally spaced
    • autoregressive process 1 (ar1) because the correlation between times differ
  2. clustered data

    • each pacient had 3 visits each with one measurement for all the haematological variables
    • dataset is in a long (tidy) format

historial

20180103

  • recepción de las bases

  • estructura:

    • Controles (n=308) del año 2010
    • Pf positivos (n=34) años 2011 y 2012
    • Pv positivos (n=93) año 2011

20181201

  • importar y limpiar base de datos

20190506

  • union de base de datos y ejecución de análisis descriptivos

20200204

  • corrección por autocorrelación debido a mediciones repetidas

citar

@software{andree_valle_campos_2020_4014205, author = {Andree Valle Campos}, title = {avallecam/hemogr: First release}, month = sep, year = 2020, publisher = {Zenodo}, version = {v0.1}, doi = {10.5281/zenodo.4014205}, url = {https://doi.org/10.5281/zenodo.4014205} }

Owner

  • Name: Andree Valle Campos
  • Login: avallecam
  • Kind: user
  • Location: Lima, Perú

pron: él/he/his, peruano, tusán.

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