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https://github.com/berenslab/dlgn_movie_spline_model

dLGN movie spline LNP model

https://github.com/berenslab/dlgn_movie_spline_model

Science Score: 13.0%

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Repository

dLGN movie spline LNP model

Basic Info
  • Host: GitHub
  • Owner: berenslab
  • License: cc0-1.0
  • Language: Jupyter Notebook
  • Default Branch: main
  • Size: 26.5 MB
Statistics
  • Stars: 0
  • Watchers: 3
  • Forks: 0
  • Open Issues: 0
  • Releases: 1
Created almost 2 years ago · Last pushed almost 2 years ago
Metadata Files
Readme License

README.md

Spline-based generalized linear model of dLGN neuron activity

Project Description

This repository contains code for analyzing the modulation of neuronal activity in the dorsolateral geniculate nucleus (dLGN) of the thalamus in awake mice. The project aims to investigate how stimulus-driven signals are combined with modulatory inputs such as corticothalamic feedback and behavioral state.

We utilized the RFEst Python toolbox for implementing a spline-based generalized linear model (GLM) to estimate spatio-temporal receptive fields (STRFs) of dLGN neurons. We extended the model to integrate additional spline kernels for pupil size, locomotion, and corticothalamic feedback.

Installation

  1. Clone this repository: https://github.com/berenslab/dLGNmoviespline_model.git
  2. Create a virtual environment and activate it: python -m venv venv source venv/bin/activate
  3. Install the required packages: pip install -r requirements.txt

License

This project is licensed under the CC0-1.0 License.

Owner

  • Name: Berens Lab @ University of Tübingen
  • Login: berenslab
  • Kind: organization
  • Email: philipp.berens@uni-tuebingen.de
  • Location: Tübingen, Germany

Department of Data Science at the Hertie Institute for AI in Brain Health, University of Tübingen

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Dependencies

requirements.txt pypi
  • jax *
  • jaxlib *
  • matplotlib *
  • numpy *
  • pandas *
  • rfest *
  • scikit-learn *
  • scipy *
  • seaborn *