https://github.com/bhklab/mycg9a

https://github.com/bhklab/mycg9a

Science Score: 13.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
  • codemeta.json file
    Found codemeta.json file
  • .zenodo.json file
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  • Scientific vocabulary similarity
    Low similarity (5.3%) to scientific vocabulary
Last synced: 10 months ago · JSON representation

Repository

Basic Info
  • Host: GitHub
  • Owner: bhklab
  • Language: R
  • Default Branch: master
  • Size: 14.6 MB
Statistics
  • Stars: 0
  • Watchers: 3
  • Forks: 1
  • Open Issues: 0
  • Releases: 0
Created about 8 years ago · Last pushed over 7 years ago
Metadata Files
Readme

README.md

MYCG9a

Introduction

This is a project to regenerate the pharmacogenomics analysis in this paper:

MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis. Tu WB, Shiah YJ, Lourenco C, Mullen PJ, Dingar D, Redel C, Tamachi A, Ba-Alawi W, Aman A, Al-Awar R, Cescon DW, Haibe-Kains B, Arrowsmith CH, Raught B, Boutros PC, Penn LZ. Cancer Cell. 2018 Oct 8.

The script for the analysis is written in R.


Dependencies:

These R packages need to be installed in order to run the analysis script: - Biobase - PharmacoGx - scales - piano - GSA


Reproducibility of the Analysis:

  • Once the project is downloaded to the user computer, the user needs to navigate to the main directory of the project "MYCG9a-master".
  • Inside the main directory, there is an R script file named "ScriptMYCG9aFigurespharmacogenomics.R". Running this script will regenerate the full pharmacogenomics analysis related to associating g9a inhibitor response with MYC regulation signatures in this paper.

Important Note: the user needs to set the working directory inside the script file before running it, i.e. setting the working directory to "MYCG9a-master"

Owner

  • Name: BHKLAB
  • Login: bhklab
  • Kind: organization
  • Location: Toronto, Ontario, Canada

The Haibe-Kains Laboratory @ Princess Margaret Cancer Centre

GitHub Events

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Last Year

Committers

Last synced: about 1 year ago

All Time
  • Total Commits: 6
  • Total Committers: 2
  • Avg Commits per committer: 3.0
  • Development Distribution Score (DDS): 0.333
Past Year
  • Commits: 0
  • Committers: 0
  • Avg Commits per committer: 0.0
  • Development Distribution Score (DDS): 0.0
Top Committers
Name Email Commits
Wail Ba alawi b****i@g****m 4
Benjamin Haibe-Kains b****a@g****m 2

Issues and Pull Requests

Last synced: about 1 year ago

All Time
  • Total issues: 0
  • Total pull requests: 0
  • Average time to close issues: N/A
  • Average time to close pull requests: N/A
  • Total issue authors: 0
  • Total pull request authors: 0
  • Average comments per issue: 0
  • Average comments per pull request: 0
  • Merged pull requests: 0
  • Bot issues: 0
  • Bot pull requests: 0
Past Year
  • Issues: 0
  • Pull requests: 0
  • Average time to close issues: N/A
  • Average time to close pull requests: N/A
  • Issue authors: 0
  • Pull request authors: 0
  • Average comments per issue: 0
  • Average comments per pull request: 0
  • Merged pull requests: 0
  • Bot issues: 0
  • Bot pull requests: 0
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