https://github.com/bioconductor-source/tronco
Science Score: 13.0%
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○CITATION.cff file
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✓codemeta.json file
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○.zenodo.json file
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○Scientific vocabulary similarity
Low similarity (7.8%) to scientific vocabulary
Repository
Basic Info
- Host: GitHub
- Owner: bioconductor-source
- License: gpl-3.0
- Language: R
- Default Branch: devel
- Size: 1.33 MB
Statistics
- Stars: 0
- Watchers: 2
- Forks: 0
- Open Issues: 0
- Releases: 0
Metadata Files
README.md
TRONCO (TRanslational ONCOlogy)
| Branch | Status |
| --- | --- |
| master | 
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| development | 
|
The TRONCO (TRanslational ONCOlogy) R package collects algorithms to infer progression models via the approach of Suppes-Bayes Causal Network, both from an ensemble of tumors (cross-sectional samples) and within an individual patient (multi-region or single-cell samples).
The package provides parallel implementation of algorithms that process binary matrices where each row represents a tumor sample and each column a single-nucleotide or a structural variant driving the progression; a 0/1 value models the absence/presence of that alteration in the sample.
The tool can import data from plain, MAF or GISTIC format files, and can fetch it from the cBioPortal for cancer genomics. Functions for data manipulation and visualization are provided, as well as functions to import/export such data to other bioinformatics tools for, e.g, clustering or detection of mutually exclusive alterations. Inferred models can be visualized and tested for their confidence via bootstrap and cross-validation.
TRONCO is used for the implementation of the Pipeline for Cancer Inference (PICNIC).
Owner
- Name: (WIP DEV) Bioconductor Packages
- Login: bioconductor-source
- Kind: organization
- Email: maintainer@bioconductor.org
- Website: https://bioconductor.org
- Repositories: 1
- Profile: https://github.com/bioconductor-source
Source code for packages accepted into Bioconductor
GitHub Events
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Dependencies
- JamesIves/github-pages-deploy-action releases/v4 composite
- actions/cache v3 composite
- actions/checkout v3 composite
- actions/upload-artifact master composite
- r-lib/actions/setup-pandoc v2 composite
- r-lib/actions/setup-r v2 composite
- R >= 4.1.0 depends
- R.matlab * imports
- RColorBrewer * imports
- Rgraphviz * imports
- bnlearn * imports
- circlize * imports
- doParallel * imports
- foreach * imports
- grDevices * imports
- graphics * imports
- grid * imports
- gridExtra * imports
- gtable * imports
- gtools * imports
- igraph * imports
- iterators * imports
- methods * imports
- parallel * imports
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- xtable * imports
- BiocGenerics * suggests
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