https://github.com/bioconductor-source/spiat
Science Score: 26.0%
This score indicates how likely this project is to be science-related based on various indicators:
-
○CITATION.cff file
-
✓codemeta.json file
Found codemeta.json file -
○.zenodo.json file
-
✓DOI references
Found 1 DOI reference(s) in README -
○Academic publication links
-
○Academic email domains
-
○Institutional organization owner
-
○JOSS paper metadata
-
○Scientific vocabulary similarity
Low similarity (10.9%) to scientific vocabulary
Repository
Basic Info
- Host: GitHub
- Owner: bioconductor-source
- License: artistic-2.0
- Language: R
- Default Branch: devel
- Size: 4.63 MB
Statistics
- Stars: 0
- Watchers: 2
- Forks: 0
- Open Issues: 0
- Releases: 0
Metadata Files
README.md
SPIAT - Spatial Image Analysis of Tissues
SPIAT (Spatial Image Analysis of Tissues) is an R package with a suite of data processing, quality control, visualization, data handling and data analysis tools. SPIAT is compatible with data generated from single-cell spatial proteomics platforms (e.g. OPAL, CODEX, MIBI). SPIAT reads spatial data in the form of X and Y coordinates of cells, marker intensities and cell phenotypes.
SPIAT includes six analysis modules that allow visualization, calculation of cell colocalization, categorization of the immune microenvironment relative to tumor areas, analysis of cellular neighborhoods, and the quantification of spatial heterogeneity, providing a comprehensive toolkit for spatial data analysis.
Installation
To install this package, start R and enter:
r
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("SPIAT")
You can also install the latest development version from Github.
r
if (!requireNamespace("devtools", quietly = TRUE)) {
install.packages("devtools")}
devtools::install_github("TrigosTeam/SPIAT")
The estimated installation time on a Windows 10 (64-bit) system is 1.5 minutes.
Vignette
The vignette with an overview of the package can be accessed from the top Menu under Articles or by clicking here.
We have published a Shiny App to assist reading and formatting spatial data into SPE objects that are compatible with SPIAT functions. Please follow the instructions here to download the Shiny App and start the journey!
Authors of the package
Yuzhou Feng, Tianpei Yang, Volkan Ozcoban, Mabel Li and John Zhu developed the package, including developing algorithms, writing code and designing the package. Yuzhou Feng and Maria Doyle did the package cleaning and wrote the tutorial. Anna Trigos conceived, supervised the work, developed algorithms and designed the package.
Paper reference
Please check our latest paper for more information!
Yuzhou Feng et al, Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments, Nature Communications (2023). DOI: 10.1038/s41467-023-37822-0
Owner
- Name: (WIP DEV) Bioconductor Packages
- Login: bioconductor-source
- Kind: organization
- Email: maintainer@bioconductor.org
- Website: https://bioconductor.org
- Repositories: 1
- Profile: https://github.com/bioconductor-source
Source code for packages accepted into Bioconductor
GitHub Events
Total
Last Year
Dependencies
- JamesIves/github-pages-deploy-action v4.4.1 composite
- actions/checkout v3 composite
- r-lib/actions/setup-pandoc v2 composite
- r-lib/actions/setup-r v2 composite
- r-lib/actions/setup-r-dependencies v2 composite
- R >= 4.2.0 depends
- SpatialExperiment >= 1.8.0 depends
- RANN >= 2.6.1 imports
- SummarizedExperiment * imports
- apcluster >= 1.4.7 imports
- dbscan >= 1.1 imports
- dittoSeq * imports
- dplyr >= 0.8.3 imports
- ggplot2 >= 3.2.1 imports
- grDevices * imports
- gridExtra >= 2.3 imports
- gtools >= 3.8.1 imports
- methods * imports
- mmand >= 1.5.4 imports
- pracma >= 2.2.5 imports
- raster * imports
- reshape2 >= 1.4.3 imports
- rlang * imports
- sp * imports
- spatstat.explore * imports
- spatstat.geom * imports
- stats * imports
- tibble >= 2.1.3 imports
- utils * imports
- vroom * imports
- BiocStyle * suggests
- ComplexHeatmap * suggests
- Rtsne * suggests
- alphahull * suggests
- elsa * suggests
- graphics * suggests
- knitr * suggests
- pkgdown * suggests
- plotly >= 4.9.0 suggests
- rmarkdown * suggests
- testthat * suggests
- umap * suggests