https://github.com/bioconductor-source/spatialdmelxsim

https://github.com/bioconductor-source/spatialdmelxsim

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  • Host: GitHub
  • Owner: bioconductor-source
  • Language: R
  • Default Branch: devel
  • Size: 189 KB
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Created almost 2 years ago · Last pushed almost 2 years ago
Metadata Files
Readme Changelog

README.md

spatialDmelxsim

Allelic counts from Combs & Fraser (2018), compiled into a SummarizedExperiment object.

Package is available on Bioconductor as of August 2021:

https://bioconductor.org/packages/spatialDmelxsim

After the package is released in October 2021:

BiocManager::install("spatialDmelxsim") suppressPackageStartupMessages(library(SummarizedExperiment)) library(spatialDmelxsim) se <- spatialDmelxsim()

The assays of se include a1 and a2. Here, a1 assay is the D simulans allelic count, a2 assay is the D melanogaster allelic count.

Data downloaded from GSE102233 as described in the publication:

Combs PA, Fraser HB (2018) Spatially varying cis-regulatory divergence in Drosophila embryos elucidates cis-regulatory logic. PLOS Genetics 14(11): e1007631. https://doi.org/10.1371/journal.pgen.1007631

R scripts

  • Script to build the SummarizedExperiment: inst/scripts/make-data.R
  • Demo of loading the data and calculating allelic ratio: vignettes/spatialDmelxsim.Rmd

Example figures of allelic ratio (simulans / total):

See vignette for details.

DOR

uif

bmm

hb

CG4500

Owner

  • Name: (WIP DEV) Bioconductor Packages
  • Login: bioconductor-source
  • Kind: organization
  • Email: maintainer@bioconductor.org

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Dependencies

DESCRIPTION cran
  • ExperimentHub * depends
  • R >= 4.1 depends
  • SummarizedExperiment * depends
  • utils * imports
  • BiocStyle * suggests
  • knitr * suggests
  • rmarkdown * suggests