https://github.com/c00jsw00/proab2

proab2

https://github.com/c00jsw00/proab2

Science Score: 13.0%

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Repository

proab2

Basic Info
  • Host: GitHub
  • Owner: c00jsw00
  • License: apache-2.0
  • Language: Python
  • Default Branch: main
  • Size: 589 KB
Statistics
  • Stars: 0
  • Watchers: 1
  • Forks: 0
  • Open Issues: 0
  • Releases: 0
Created about 1 year ago · Last pushed about 1 year ago
Metadata Files
Readme License

README.md

proab2

  1. conda env create -f environment.yml

  2. Download AbRSA from the official repository (http://aligncdr.labshare.cn/aligncdr/download.html) and extract the archive.

  3. Modify the ABRSAPATH variable in the autogenerate_config-final.py script to point to your AbRSA installation directory.

  4. Obtain antibody-protein complex structures from the chai-1 server and place the prediction files (pred.rank0.cif through pred.rank4.cif) in the execution directory.

  5. Run autogenerateconfig-final.py to generate the configuration file inputconfigcif.txt.

  6. python fix-integrated-gbsa-analyzer-2.py -c inputconfigcif.txt -o results -s 2000000 --stride 100

This procedure will perform molecular dynamics simulation analysis with 2,000,000 steps and sampling every 100 steps, outputting the results to the "results" directory.

Owner

  • Name: Phil Wang
  • Login: c00jsw00
  • Kind: user
  • Location: Kaohsioung
  • Company: Kaohsioung Medical University

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Dependencies

environment.yml pypi
  • biopython ==1.85
  • freesasa ==2.2.1
  • numpy ==2.2.4
  • pandas ==2.2.3
  • python-dateutil ==2.9.0.post0
  • pytz ==2025.1
  • six ==1.17.0
  • tzdata ==2025.1