https://github.com/cbg-ethz/pyggdrasil - v0.2.0

PYggdrasil v0.2.0 Release Notes

PYggdrasil v0.2.0 implements the Single Cell Inference of Tumor Evolution (SCITE) algortihm by Kuipers J et al. (2015).

It was designed to quantify the Markov chain Monte Carlo exploration of tumour progression tree spaces, in particular to investigate: - Initialisation Strategies - Convergence Diagnostics - Multi-modalities

Although PYggdrasil doesn't currently implement all features of SCITE, it enables running complex snakemake workflows for reproducible experiments.

This version allows to reproduce all experiments conducted in Gordon J Köhn's MSc Thesis: Quantifying MCMC Exploration of Tumour Progression Tree Spaces.

- Python
Published by gordonkoehn almost 3 years ago