https://github.com/cbg-ethz/myeloid-clustering

This repository contains supplementary information, data and code for the manuscript: Bayer et al. 2023, "Network-based clustering unveils interconnected landscapes of genomic and clinical features across myeloid malignancies"

https://github.com/cbg-ethz/myeloid-clustering

Science Score: 13.0%

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  • CITATION.cff file
  • codemeta.json file
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    Found 2 DOI reference(s) in README
  • Academic publication links
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    Low similarity (12.6%) to scientific vocabulary

Keywords

acute-myeloid-leukemia bayesian-networks cancer-genomics clustering myelodysplasticsyndome network-based-stratification
Last synced: 6 months ago · JSON representation

Repository

This repository contains supplementary information, data and code for the manuscript: Bayer et al. 2023, "Network-based clustering unveils interconnected landscapes of genomic and clinical features across myeloid malignancies"

Basic Info
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acute-myeloid-leukemia bayesian-networks cancer-genomics clustering myelodysplasticsyndome network-based-stratification
Created over 2 years ago · Last pushed about 1 year ago
Metadata Files
Readme License

README.md

Network-Based Clustering Unveils Interconnected Landscapes of Genomic and Clinical Features Across Myeloid Malignancies

This repository provides supplementary information, data, and code associated with the manuscript:

Bayer et al. 2023, "Network-based clustering unveils interconnected landscapes of genomic and clinical features across myeloid malignancies"

https://doi.org/10.1101/2023.10.25.563992

Online Tool

We have also developed an online tool for the classification of new patients across myeloid malignancies. Access it here:

Myeloid Malignancies Prediction Tool

Software

The software is available as an R package, which is hosted on CRAN. For more information on how to use this software, including installation, system requirements and application, please refer to our detailed documentation. - CRAN Package: Software Package - Installation and Example: Code Demo - Documentation: Software Documentation (PDF)

Reproducibility

The numerical simulations can be reproduced via the numerical_simulations folder. The results on the public TCGA datasets can be reproduced by running the files in the tcga_analysis folder. Given the full set of MDA data, all results and figures of the pan-myeloid analysis can be reproduced by running the files provied in the analysis folder. The cluster results from the pan-myeloid clustering analysis can be reproduced by running the code provided in the euler_cluster folder.

Screenshot 2023-10-31 at 08 46 43

License

GNU GPL (see LICENSE file for more details)

Owner

  • Name: Computational Biology Group (CBG)
  • Login: cbg-ethz
  • Kind: organization
  • Location: Basel, Switzerland

Beerenwinkel Lab at ETH Zurich

GitHub Events

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  • Avg Commits per committer: 11.0
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Fritz Bayer f****r@y****m 11
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