Science Score: 57.0%

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Repository

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  • Host: GitHub
  • Owner: DrPaulValle
  • License: bsd-2-clause
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Metadata Files
Readme License Citation

README.md

Open in MATLAB Online

Combined application of CAR-T cells and chlorambucil for CLL treatment: Insights from nonlinear dynamical systems and model-based design for dose finding

Paul A. Valle¹, Luis N. Coria¹, Yolocuauhtli Salazar², Corina Plata¹ and Luis A. Ramirez¹

¹Postgraduate Program in Engineering Sciences, BioMath Research Group, Tecnológico Nacional de México / IT Tijuana, Blvd. Alberto Limón Padilla s/n, Tijuana 22454, Mexico

²Postgraduate Program in Engineering. Tecnológico Nacional de México / IT Durango, Blvd. Felipe Pescador 1830 Ote., Durango 34080, Mexico

Corresponding authors: paul.valle@tectijuana.edu.mx; luis.coria@tectijuana.edu.mx

Keywords

Asymptotic stability; Cancer; CAR-T cells; Chlorambucil; In silico; Leukemia; Nonlinear system; ODEs, Treatment protocol.

Reference

Valle, P. A., Coria, L. N., Salazar, Y., Plata, C., & Ramirez, L. A. (2025). Combined Application of CAR-T Cells and Chlorambucil for CLL Treatment: Insights from Nonlinear Dynamical Systems and Model-Based Design for Dose Finding. Hemato, 6(2), 9. https://doi.org/10.3390/hemato6020009

Owner

  • Name: Paul Uchiha
  • Login: DrPaulValle
  • Kind: user
  • Company: Tecnológico Nacional de México

Citation (CITATION.cff)

# This CITATION.cff file was generated with cffinit.
# Visit https://bit.ly/cffinit to generate yours today!

cff-version: 1.2.0
title: CLL nonlinear dynamical system
message: >-
  MATLAB Digital Twin for model-based design for dose
  finding: CAR-T cells and chlorambucil for the treatment of
  CLL
type: software
authors:
  - given-names: Paul A.
    family-names: Valle
    email: paul.valle@tectijuana.edu.mx
    affiliation: Tecnológico Nacional de México
    orcid: 'https://orcid.org/0000-0001-6567-1065'
repository-code: 'https://github.com/DrPaulValle/CLL-system-Hemato-'
url: 'https://biomath.xyz/'
keywords:
  - Asymptotic stability
  - Cancer
  - CAR-T cells
  - Chlorambucil
  - In silico
  - Leukemia
  - Nonlinear system
  - ODEs
  - Treatment protocol
license: BSD-2-Clause

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