soprano

SelectiOn in PRotein ANnotated regiOns. Adapted dN/dS based method to detect selection in specific protein regions

https://github.com/instituteofcancerresearch/soprano

Science Score: 36.0%

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Repository

SelectiOn in PRotein ANnotated regiOns. Adapted dN/dS based method to detect selection in specific protein regions

Basic Info
Statistics
  • Stars: 3
  • Watchers: 0
  • Forks: 0
  • Open Issues: 13
  • Releases: 2
Created almost 3 years ago · Last pushed about 1 year ago
Metadata Files
Readme License Citation

README.md

SOPRANO

Selection On PRotein ANnotated regiOns


This can be accessed via the webserver: soprano-app

Main Tests Dev Tests Python 3.10|11

The SOPRANO method was developed to quantify selection in specific regions of the genome. It calculates ON- and OFF-target dN/dS using a set of annotated somatic point mutations and a transcript coordinates file.

This repository is a Python reimplementation of the original method with two main offerings:

  1. An application interface to easily pre-process the relevant input files.
  2. A scalable command line utility to run the SOPRANO pipeline for dN/dS, serving local and high-performance computing environments, distributed over MPI.

Quick links

  • Documentation is available on this site.

  • Issues should be raised here.

  • Reference the SOPRANO method with Zapata et al.

  • View the original repository here.

Owner

  • Name: The Institute of Cancer Research
  • Login: instituteofcancerresearch
  • Kind: organization
  • Location: United Kingdom

Making the discoveries that defeat cancer.

GitHub Events

Total
  • Issues event: 6
  • Issue comment event: 3
  • Push event: 13
  • Pull request review event: 1
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Last Year
  • Issues event: 6
  • Issue comment event: 3
  • Push event: 13
  • Pull request review event: 1
  • Pull request event: 4
  • Create event: 2

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Last synced: 10 months ago

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Past Year
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  • Average comments per pull request: 0
  • Merged pull requests: 0
  • Bot issues: 0
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Top Authors
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  • bkmarzouk (11)
  • rachelicr (3)
  • faizjab (2)
  • LongpanUPC (1)
  • Y-u-q-i (1)
  • myy1823 (1)
  • msarkis-icr (1)
Pull Request Authors
  • bkmarzouk (20)
  • rachelicr (9)
  • msarkis-icr (1)
Top Labels
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enhancement (8) bug (2) active (2)
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enhancement (4)

Dependencies

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