Geometric models reveal behavioural and neural signatures of transforming naturalistic experiences into episodic memories

This repository contains data and code used to produce the paper "Geometric models reveal behavioural and neural signatures of transforming naturalistic experiences into episodic memories" by Andrew C. Heusser, Paxton C. Fitzpatrick, and Jeremy R. Manning.

The repository is organized as follows:

yaml root code : all analysis code used in the paper notebooks : Jupyter notebooks for paper analyses scripts : Python scripts for running analyses on a HPC cluster (Moab/TORQUE) embedding : scripts for optimizing the UMAP embedding for the trajectory figure searchlights : scripts for performing the brain searchlight analyses sherlock_helpers : Python package with support code for analyses data : all data analyzed in the paper raw : raw video annotations and recall transcripts processed : all processed data paper : all files to generate paper figs : pdf copies of all figures

We also include a Dockerfile to reproduce our computational environment. Instruction for use are below (copied and modified from the MIND repo):

One time setup

1. Install Docker on your computer using the appropriate guide below:
   • OSX
   • Windows
   • Ubuntu
   • Debian
2. Launch Docker and adjust the preferences to allocate sufficient resources (e.g. >= 4GB RAM)
3. To build the Docker image, open a terminal window, navigate to your local copy of the repo, and run docker build -t sherlock .
   
4. Use the image to run a container with the repo mounted as a volume so the code and data are accessible.
   • The command below will create a new container that maps the repository on your computer to the /mnt directory within the container, so that location is shared between your host OS and the container. Be sure to replace LOCAL/REPO/PATH with the path to the cloned repository on your own computer (you can get this by navigating to the repository in the terminal and typing pwd). The below command will also share port 9999 with your host computer, so any Jupyter notebooks launched from within the container will be accessible at localhost:9999 in your web browser
   • docker run -it -p 9999:9999 --name Sherlock -v /LOCAL/REPO/PATH:/mnt sherlock
   • You should now see the root@ prefix in your terminal. If you do, then you've successfully created a container and are running a shell from inside!
5. To launch any of the notebooks, simply enter jupyter notebook and copy/paste the link generated into your browser.

Using the container after setup

1. You can always fire up the container by typing the following into the terminal
   • docker start Sherlock && docker attach Sherlock
   • When you see the root@ prefix, letting you know you're inside the container
2. If you launch the notebooks, you'll notice your shell is occupied by the output log from the jupyter server. To stop the notebook server, press ctrl + c, and then y when prompted.
3. To close the running container, press ctrl + d or type exit from the same terminal window you used to launch the container.
4. You can also open a second bash shell inside the container simultaneously by running docker exec -it Sherlock bash from the terminal outside the container. Note that when you enter the container this way (rather than by using docker attach Sherlock), the container isn't automatically stopped when you exit it. To stop the container after exiting, enter docker stop Sherlock.