drug-database

Command line interface for getting info about drugs

https://github.com/computationalphysiology/drug-database

Science Score: 44.0%

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Repository

Command line interface for getting info about drugs

Basic Info
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  • Stars: 1
  • Watchers: 3
  • Forks: 0
  • Open Issues: 0
  • Releases: 1
Created over 3 years ago · Last pushed over 3 years ago
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Readme License Citation

README.md

MIT Test package pre-commit Deploy static content to Pages PyPI version

Drug database

Simple command line interface for getting scaling factors for different drugs

  • Documentation: https://ComputationalPhysiology.github.io/drug-database/
  • Source code: https://github.com/ComputationalPhysiology/drug-database

Install

$ python -m pip install drug-database Once installed you will get access to the drug-db command.

Usage

Get help using $ drug-db --help

List all available drugs

$ drug-db list-drugs Drugs ┏━━━━━━━━━━━━━━━━┓ ┃ Name ┃ ┡━━━━━━━━━━━━━━━━┩ │ Sotalol │ │ Azimilide │ │ Ibutilide │ │ Risperidone │ │ Clarithromycin │ │ Terfenadine │ │ Bepridil │ │ Pimozide │ │ Dofetilide │ │ Disopyramide │ │ Cisapride │ │ Tamoxifen │ │ Vandetanib │ │ Metropolol │ │ Droperidol │ │ Loratadine │ │ Ranolazine │ │ Quinidine │ │ Diltiazem │ │ Astemizole │ │ Nitrendipine │ │ Chlorpromazine │ │ Clozapine │ │ Control │ │ Nifedipine │ │ Verapamil │ │ Domperidone │ │ Ondansetron │ │ Mexiletine │ └────────────────┘

Showing information about specific drug

$ drug-db show-drug Verapamil Scaling factors for drug Verapamil and FPC 1 ┏━━━━━━━━━━━━━━━━━━━┳━━━━━━━━┓ ┃ Name ┃ Value ┃ ┡━━━━━━━━━━━━━━━━━━━╇━━━━━━━━┩ │ scale_drug_INa │ 1.0 │ │ scale_drug_INaL │ 1.0 │ │ scale_drug_Ito │ 1.0 │ │ scale_drug_ICaL │ 0.7342 │ │ scale_drug_IKr │ 0.8815 │ │ scale_drug_IKs │ 1.0 │ │ scale_drug_IK1 │ 1.0 │ │ scale_drug_IKb │ 1.0 │ │ scale_drug_INab │ 1.0 │ │ scale_drug_ICab │ 1.0 │ │ scale_drug_IpCa │ 1.0 │ │ scale_drug_Isacns │ 1.0 │ │ scale_drug_Isack │ 1.0 │ └───────────────────┴────────┘

Note that this is showing the values that are 1 times FPC (FIXME: explain what this means). If you want to get the values for 5 times FPC the you can do $ drug-db show-drug Verapamil --fpc 5 Scaling factors for drug Verapamil and FPC 5 ┏━━━━━━━━━━━━━━━━━━━┳━━━━━━━━┓ ┃ Name ┃ Value ┃ ┡━━━━━━━━━━━━━━━━━━━╇━━━━━━━━┩ │ scale_drug_INa │ 1.0 │ │ scale_drug_INaL │ 0.9997 │ │ scale_drug_Ito │ 1.0 │ │ scale_drug_ICaL │ 0.3199 │ │ scale_drug_IKr │ 0.5588 │ │ scale_drug_IKs │ 1.0 │ │ scale_drug_IK1 │ 1.0 │ │ scale_drug_IKb │ 1.0 │ │ scale_drug_INab │ 1.0 │ │ scale_drug_ICab │ 1.0 │ │ scale_drug_IpCa │ 1.0 │ │ scale_drug_Isacns │ 1.0 │ │ scale_drug_Isack │ 1.0 │ └───────────────────┴────────┘

json support

By default the tables are displayed in a Rich table, however sometimes you might want to use these values in another program in which you can convert the values to json by using the --json flag, e.g $ drug-db show-drug Verapamil --fpc 5 --json {"scale_drug_INa": 1.0, "scale_drug_INaL": 0.9997, "scale_drug_Ito": 1.0, "scale_drug_ICaL": 0.3199, "scale_drug_IKr": 0.5588, "scale_drug_IKs": 1.0, "scale_drug_IK1": 1.0, "scale_drug_IKb": 1.0, "scale_drug_INab": 1.0, "scale_drug_ICab": 1.0, "scale_drug_IpCa": 1.0, "scale_drug_Isacns": 1.0, "scale_drug_Isack": 1.0} You can also save this to a file using e.g $ drug-db show-drug Verapamil --fpc 5 --json > verapamil_5.json

License

MIT

Author

Henrik Finsberg (henriknf@simula.no)

Owner

  • Name: Computational Physiology at Simula Research Laboratory
  • Login: ComputationalPhysiology
  • Kind: organization
  • Location: Fornebu, Norway

GitHub organization for the computational physiology department at Simula Research Laboratory

Citation (CITATION.cff)

cff-version: 1.2.0
message: "If you use this software, please cite it as below."
authors:
- family-names: "Finsberg"
  given-names: "Henrik"
title: "drug-database"
version: "0.1.0"
date-released: 2022-12-07

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  • Total packages: 1
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    • pypi 15 last-month
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  • Total dependent repositories: 1
  • Total versions: 3
  • Total maintainers: 1
pypi.org: drug-database

Tool for getting scaling factors from different drugs

  • Documentation: https://drug-database.readthedocs.io/
  • License: Copyright 2022 Henrik Finsberg Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.
  • Latest release: 0.1.3
    published over 3 years ago
  • Versions: 3
  • Dependent Packages: 0
  • Dependent Repositories: 1
  • Downloads: 15 Last month
Rankings
Dependent packages count: 10.0%
Dependent repos count: 21.7%
Average: 29.6%
Downloads: 57.2%
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Last synced: 8 months ago

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