projects-a01

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https://github.com/sfb1451/projects-a01

Science Score: 44.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
    Found CITATION.cff file
  • codemeta.json file
    Found codemeta.json file
  • .zenodo.json file
    Found .zenodo.json file
  • DOI references
  • Academic links in README
  • Academic email domains
  • Institutional organization owner
  • JOSS paper metadata
  • Scientific vocabulary similarity
    Low similarity (0.4%) to scientific vocabulary
Last synced: 6 months ago · JSON representation ·

Repository

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Basic Info
  • Host: GitHub
  • Owner: sfb1451
  • Default Branch: sfb-retreat-2023
  • Size: 149 KB
Statistics
  • Stars: 1
  • Watchers: 2
  • Forks: 0
  • Open Issues: 0
  • Releases: 0
Created over 2 years ago · Last pushed over 2 years ago
Metadata Files
Citation

Owner

  • Name: sfb1451
  • Login: sfb1451
  • Kind: organization

Citation (CITATION.cff)

abstract: Project A01 focuses on the mechanisms underlying motor neuron function and
  plasticity by investigating the protective role of Plastin 3 (PLS3) in a mouse model
  of spinal muscular atrophy (SMA). The protective effect of PLS3 will be further
  analysed in amyotrophic lateral sclerosis (ALS), a second motor neuron disease,
  to verify the cross-disease protective potency. Two putative pathomechanisms, i.e.,
  disturbed Caveolin-dependent endocytosis and calcium homeostasis, will be investigated
  by molecular, cellular, and in vivo methods in genetically modified SMA and ALS
  mouse models, overexpressing PLS3.
authors:
- {family-names: Wirth, given-names: Brunhilde}
- {family-names: Kloppenburg, given-names: Peter}
- {family-names: Radermacher, given-names: Jan Erik}
- {family-names: Zilio, given-names: Eleonora}
cff-version: 1.2.0
message: Generated with data scraped from crc1451.uni-koeln.de
title: 'A01: Understanding plastin 3 and its interactors in motor neuron function
  and plasticity in health and disease'

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