qq-hahnecho

Analysis of Conformational Exchange Processes using Methyl-TROSY-Based Hahn Echo Measurements of Quadruple-Quantum Relaxation

https://github.com/chriswaudby/qq-hahnecho

Science Score: 54.0%

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Repository

Analysis of Conformational Exchange Processes using Methyl-TROSY-Based Hahn Echo Measurements of Quadruple-Quantum Relaxation

Basic Info
  • Host: GitHub
  • Owner: chriswaudby
  • License: mit
  • Language: Julia
  • Default Branch: main
  • Size: 21.7 MB
Statistics
  • Stars: 0
  • Watchers: 1
  • Forks: 0
  • Open Issues: 0
  • Releases: 2
Created over 4 years ago · Last pushed over 4 years ago
Metadata Files
Readme License Citation

README.md

qq-hahnecho

DOI

Code for Analysis of Conformational Exchange Processes using Methyl-TROSY-Based Hahn Echo Measurements of Quadruple-Quantum Relaxation.

This repository contains code for three analyses: * hahnecho-analysis - analysis of field-dependent Hahn echo measurements for single residues (Fig. 5 in publication) * hahnecho-cpmg-analysis - global fitting of Hahn echo and CPMG data (Fig. 6 in publication) * pseudo3d-fitting - pseudo-3D lineshape fitting for determination of S2tc and 13C CSA (Fig. 3 in publication)

Pulse sequences and processing scripts are also provided in the pp directory.

Analysis scripts are written in Julia. Dependencies for both analyses are contained in the Project.toml file, and can be set up from the package manager by running ] instantiate in the top level directory. Individual analyses should then be run from within the appropriate directory.

Analysis of individual field-dependent Hahn echo measurements

  • Directory: hahnecho-analysis
  • Main file: go.jl
  • All data are contained within data subdirectory.

Global Hahn echo and CPMG analysis

  • Directory: hahnecho-cpmg-analysis
  • Main file: go.jl
  • All data are contained within data subdirectory. CPMG data are loaded from parsed ChemEx format.

Pseudo-3D lineshape fitting of 1H-coupled relaxation-weighted HSQC

  • Directory: pseudo3d-fitting
  • Main file: go.jl
  • All data are contained within data subdirectory.

Citing

If you use this software, please cite it: see CITATION.cff for further information.

Owner

  • Name: Chris Waudby
  • Login: chriswaudby
  • Kind: user

Citation (CITATION.cff)

# YAML 1.2
---
authors: 
  -
    family-names: Waudby
    given-names: "Christopher Andrew"
    orcid: "https://orcid.org/0000-0001-7810-3753"
  - family-names: "Christodoulou"
    given-names: "John"
    orcid: "https://orcid.org/0000-0002-6710-3843"
cff-version: "1.1.0"
date-released: 2021-10-10
doi: 
license: MIT
message: "If you use this software, please cite it using these metadata."
repository-code: "https://github.com/chriswaudby/qq-hahnecho"
title: "QQ Hahn Echo and CPMG analysis"
preferred-citation:
  type: article
  authors:
  - family-names: "Waudby"
    given-names: "Christopher Andrew"
    orcid: "https://orcid.org/0000-0001-7810-3753"
  - family-names: "Christodoulou"
    given-names: "John"
    orcid: "https://orcid.org/0000-0002-6710-3843"
  doi: "10.5194/mr-2021-60"
  url: "https://mr.copernicus.org/preprints/mr-2021-60/"
  journal: "Magnetic Resonance Discussions"
  month: 9
  start: 1 # First page number
  end: 23 # Last page number
  title: "Analysis of Conformational Exchange Processes using Methyl-TROSY-Based Hahn Echo Measurements of Quadruple-Quantum Relaxation"
  issue: 1
  volume: 2021
  year: 2021
...

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