spreading-depolarization

Analysis scripts related to manuscript "Hippocampal stroke in freely behaving mice reveals sex differences in presentation and behavioural impact of contralesional spreading depolarization"

https://github.com/leomol/spreading-depolarization

Science Score: 44.0%

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CITATION.cff file
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Low similarity (7.3%) to scientific vocabulary

Last synced: 9 months ago · JSON representation ·

Repository

Analysis scripts related to manuscript "Hippocampal stroke in freely behaving mice reveals sex differences in presentation and behavioural impact of contralesional spreading depolarization"

Basic Info

Host: GitHub
Owner: leomol
Language: MATLAB
Default Branch: master
Size: 28.3 KB

Statistics

Stars: 0
Watchers: 1
Forks: 0
Open Issues: 0
Releases: 3

Created almost 3 years ago · Last pushed over 1 year ago

Metadata Files

Readme Changelog Citation

Description

Analysis scripts related to the manuscript "Changes in open field activity, bilateral local field potential (ie. epileptiform activity) and bilateral GCaMP photometry (ie. spreading depolarizations) after unilateral photothrombosis"

Prerequisites

MATLAB (last tested with R2023b)
FPA library

Installation

Install MATLAB
Download and extract the FPA library to the Documents/MATLAB folder (see FPA's installation instructions for the required toolboxes)
Download and extract the spreading-depolarization scripts to the Documents/MATLAB folder.

Usage

Go to the FPA folder and run startup.m to add FPA dependencies to the MATLAB search path.
Go to the spreading-depolarization folder and run startup.m to download example data. Remove startup.m and/or the data if you do not require these data.
Edit analysis1.m to match your experimental configuration (e.g. path to files and column numbers, etc) then run to pre-process fibre-photometry data to get behavior triggered data.
Run analysis2.m to detect peak derivatives in ipsilesional GCaMP6f related to stroke.
Run analysis3.m to detect epileptiform activity in bilateral local field potential recordings relative to simultaneous bilateral fibre photometry recordings.

Changelog

See Changelog

Owner

Name: Leo
Login: leomol
Kind: user

Repositories: 5
Profile: https://github.com/leomol

Citation (CITATION.cff)

cff-version: 1.2.0
title: "Changes in open field activity, epileptiform activity and spreading depolarizations after unilateral photothrombosis"
abstract: "Analysis scripts related to the manuscript Changes in open field activity, epileptiform activity and spreading depolarizations after unilateral photothrombosis"
message: If you use these scripts, please cite the repository.
type: software
version: 0.0.2
doi: 10.5281/zenodo.8303055
date-released: 2023-08-30
repository-code: https://github.com/leomol/spreading-depolarizations
authors:
  - family-names: "Molina"
    given-names: "Leonardo A."
    email: "leonardo.molina@ucalgary.ca"
    affiliation: "University of Calgary"
    orcid: https://orcid.org/0000-0002-6601-7185
  - family-names: "Nicola"
    given-names: "Wilten"
    email: "wilten.nicola@ucalgary.ca"
    affiliation: "University of Calgary"
    orcid: https://orcid.org/0000-0002-8745-2899
  - family-names: "Boyce"
    given-names: "Andrew K.J"
    email: "andrew.boyce@ucalgary.ca"
    affiliation: "University of Calgary"
    orcid: https://orcid.org/0000-0002-3708-9884

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