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https://github.com/kull-centre/_2022_norrild_gmma_trx

Increasing protein stability by inferring substitution effects from high-throughput experiments

https://github.com/kull-centre/_2022_norrild_gmma_trx

Science Score: 18.0%

This score indicates how likely this project is to be science-related based on various indicators:

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    CITATION.cff file
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    codemeta.json file
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    .zenodo.json file
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    DOI references
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    Academic publication links
    Links to: zenodo.org
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    Institutional organization owner
    Organization kull-centre has institutional domain (www1.bio.ku.dk)
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    Scientific vocabulary similarity
    Low similarity (4.8%) to scientific vocabulary
Last synced: 4 months ago · JSON representation

Repository

Increasing protein stability by inferring substitution effects from high-throughput experiments

Basic Info
  • Host: GitHub
  • Owner: KULL-Centre
  • Language: Jupyter Notebook
  • Default Branch: main
  • Size: 143 MB
Statistics
  • Stars: 1
  • Watchers: 2
  • Forks: 0
  • Open Issues: 0
  • Releases: 0
Created over 3 years ago · Last pushed over 3 years ago

https://github.com/KULL-Centre/_2022_Norrild_GMMA_TRX/blob/main/ 

# _2022_Norrild_GMMA_TRX
Scripts and output from "Increasing protein stability by inferring substitution effects from high-throughput experiments" by Rasmus K. Norrild, Kristoffer E. Johansson, Charlotte OShea, Jens Preben Morth, Kresten Lindorff-Larsen and Jakob R. Winther

Directories
- variant_call_scripts: Code mentioned in the article used for processing FASTQ files
- data: Raw data from the CPOP screen and computational methods including plots
- GMMA: Software, input and output files. The analysis is implemented in R and split into 5 scripts (gmma01-gmma05), see run.sh. The excel file trx_gmma.xlsx contains all 3 output files residue.txt, subst.csv and mutant.csv.
- nano_dsf: Data and notebook for stability measurements

Sequencing reads are available at https://erda.ku.dk/archives/66b4989dbfdc6374ba673594df195465/published-archive.html

[![DOI](https://zenodo.org/badge/551334135.svg)](https://zenodo.org/badge/latestdoi/551334135)

Owner

  • Name: Linderstrøm-Lang Centre for Protein Science, University of Copenhagen
  • Login: KULL-Centre
  • Kind: organization
  • Location: Copenhagen, Denmark

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