feflow

Recipes and protocols for molecular free energy calculations using the openmmtools/perses and Open Free Energy toolkits

https://github.com/openfreeenergy/feflow

Science Score: 77.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
    Found CITATION.cff file
  • codemeta.json file
    Found codemeta.json file
  • .zenodo.json file
    Found .zenodo.json file
  • DOI references
    Found 4 DOI reference(s) in README
  • Academic publication links
    Links to: zenodo.org
  • Committers with academic emails
    1 of 7 committers (14.3%) from academic institutions
  • Institutional organization owner
  • JOSS paper metadata
  • Scientific vocabulary similarity
    Low similarity (7.5%) to scientific vocabulary

Keywords from Contributors

computational-chemistry atom-mapping free-energy-calculations hybrid-topology openfe molecular-dynamics
Last synced: 6 months ago · JSON representation ·

Repository

Recipes and protocols for molecular free energy calculations using the openmmtools/perses and Open Free Energy toolkits

Basic Info
  • Host: GitHub
  • Owner: OpenFreeEnergy
  • License: mit
  • Language: Python
  • Default Branch: main
  • Size: 250 KB
Statistics
  • Stars: 14
  • Watchers: 6
  • Forks: 2
  • Open Issues: 55
  • Releases: 4
Created over 2 years ago · Last pushed 6 months ago
Metadata Files
Readme Changelog License Code of conduct Citation

README.md

FE Flow

GitHub Actions Build Status codecov DOI

Recipes, utilities, and protocols for molecular free energy calculations using the openmmtools/perses and Open Free Energy toolkits

Copyright

Copyright (c) 2023, ChoderaLab Copyright (c) 2024, The Open Free Energy development team

Acknowledgements

Choderalab -- Perses

Open Free Energy Consortium

Project based on the Computational Molecular Science Python Cookiecutter version 1.1.

References

[1] Van Der Walt, S., Colbert, S.C. & Varoquaux, G., 2011. The NumPy array: a structure for efficient numerical computation. Computing in Science & Engineering, 13(2), pp.22–30.

[2] Identifying and Overcoming the Sampling Challenges in Relative Binding Free Energy Calculations of a Model Protein:Protein Complex Ivy Zhang, Dominic A. Rufa, Iván Pulido, Michael M. Henry, Laura E. Rosen, Kevin Hauser, Sukrit Singh, and John D. Chodera Journal of Chemical Theory and Computation 2023 19 (15), 4863-4882 DOI: 10.1021/acs.jctc.3c00333

[3] Chodera, J. et al., 2023. choderalab/openmmtools: 0.23.1.

[4] Eastman, P. et al., 2017. OpenMM 7: Rapid development of high performance algorithms for molecular dynamics R. Gentleman, ed.. PLOS Computational Biology, 13(7), p.1005659.

Owner

  • Name: Open Free Energy
  • Login: OpenFreeEnergy
  • Kind: organization

Citation (CITATION.cff)

# This CITATION.cff file was generated with cffinit.
# Visit https://bit.ly/cffinit to generate yours today!

cff-version: 1.2.0
title: FEflow
message: >-
  If you use this software, please cite it using the
  metadata from this file.
type: software
authors:
  - given-names: Iván
    family-names: Pulido Sánchez
    orcid: 'https://orcid.org/0000-0002-7178-8136'
  - given-names: Irfan
    family-names: Alibay
    orcid: 'https://orcid.org/0000-0001-5787-9130'
  - given-names: David
    family-names: Dotson
    orcid: 'https://orcid.org/0000-0001-5879-2942'
  - given-names: Richard
    family-names: Gowers
    orcid: 'https://orcid.org/0000-0002-3241-1846'
  - given-names: Hannah
    family-names: Baumann
    orcid: 'https://orcid.org/0000-0002-1736-7744'
  - given-names: Michael M.
    family-names: Henry
    orcid: 'https://orcid.org/0000-0002-3870-9993'
repository-code: 'https://github.com/OpenFreeEnergy/feflow'
version: '0.1'
date-released: '2024-07-29'

GitHub Events

Total
  • Create event: 15
  • Release event: 3
  • Issues event: 16
  • Watch event: 2
  • Delete event: 14
  • Issue comment event: 50
  • Push event: 56
  • Pull request review comment event: 11
  • Pull request review event: 23
  • Pull request event: 31
  • Fork event: 1
Last Year
  • Create event: 15
  • Release event: 3
  • Issues event: 16
  • Watch event: 2
  • Delete event: 14
  • Issue comment event: 50
  • Push event: 56
  • Pull request review comment event: 11
  • Pull request review event: 23
  • Pull request event: 31
  • Fork event: 1

Committers

Last synced: 8 months ago

All Time
  • Total Commits: 80
  • Total Committers: 7
  • Avg Commits per committer: 11.429
  • Development Distribution Score (DDS): 0.387
Past Year
  • Commits: 31
  • Committers: 7
  • Avg Commits per committer: 4.429
  • Development Distribution Score (DDS): 0.581
Top Committers
Name Email Commits
Iván Pulido 2****s 49
David Dotson d****l@g****m 14
pre-commit-ci[bot] 6****] 5
Mike Henry 1****y 4
jthorton J****n@n****k 4
Irfan Alibay I****y 3
Ethan Holz e****z@t****m 1
Committer Domains (Top 20 + Academic)

Issues and Pull Requests

Last synced: 6 months ago

All Time
  • Total issues: 64
  • Total pull requests: 67
  • Average time to close issues: 3 months
  • Average time to close pull requests: 28 days
  • Total issue authors: 10
  • Total pull request authors: 9
  • Average comments per issue: 0.75
  • Average comments per pull request: 1.72
  • Merged pull requests: 48
  • Bot issues: 0
  • Bot pull requests: 7
Past Year
  • Issues: 32
  • Pull requests: 35
  • Average time to close issues: 26 days
  • Average time to close pull requests: 6 days
  • Issue authors: 8
  • Pull request authors: 7
  • Average comments per issue: 0.72
  • Average comments per pull request: 1.2
  • Merged pull requests: 24
  • Bot issues: 0
  • Bot pull requests: 5
Top Authors
Issue Authors
  • ijpulidos (24)
  • IAlibay (11)
  • jthorton (2)
  • dotsdl (2)
  • mikemhenry (2)
  • atravitz (1)
  • jameseastwood (1)
  • sukritsingh (1)
Pull Request Authors
  • ijpulidos (37)
  • mikemhenry (10)
  • pre-commit-ci[bot] (9)
  • IAlibay (9)
  • jthorton (4)
  • dotsdl (4)
  • richardjgowers (2)
  • ethanholz (2)
  • ianmkenney (1)
Top Labels
Issue Labels
enhancement (2) priority:medium (1) testing (1) openfe (1)
Pull Request Labels

Dependencies

pyproject.toml pypi