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platform-docs

https://platform-docs.opentargets.org/

https://github.com/opentargets/platform-docs

Science Score: 44.0%

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    Found CITATION.cff file
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    Low similarity (10.1%) to scientific vocabulary
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Repository

https://platform-docs.opentargets.org/

Basic Info
  • Host: GitHub
  • Owner: opentargets
  • Default Branch: main
  • Size: 5.43 MB
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Created over 4 years ago · Last pushed 9 months ago
Metadata Files
Readme Citation

README.md

Open Targets Platform

Welcome!

The Open Targets Platform is a comprehensive tool that supports systematic identification and prioritisation of potential therapeutic drug targets.

By integrating publicly available datasets including data generated by the Open Targets consortium, the Platform builds and scores target-disease associations to assist in drug target identification and prioritisation. It also integrates relevant annotation information about targets, diseases/phenotypes, drugs, variants, studies, and credible sets as well as their most relevant relationships.

The Platform is a freely available resource that is actively maintained with quarterly updates. Our data can be accessed through an intuitive web user interface, an API, and data downloads. Likewise, our pipeline and infrastructure codebases are open-source and can be used to create a self-hosted private instance of the Platform with custom data. For more information, please review our Licence documentation and, if you use our data and/or pipelines, please cite our latest publication.

Check out our blog to learn more about the Platform and the Open Targets research programme.

You can also join the Open Targets Community and follow us on:

For additional help with the Open Targets Platform, or to report bugs, data issues, or submit a feature request, please post on the Open Targets Community, using the relevant categories and tags. If the request you would like to make has already been posted, please like the post to indicate you would like this to be prioritised.

{% embed url="https://www.youtube.com/watch?v=cuutCYPiYuw" %}

Owner

  • Name: Open Targets
  • Login: opentargets
  • Kind: organization

An innovative, multi-year, industry-academia partnership that generates research insights to support systematic drug target identification and prioritisation

Citation (citation.md) 

# Citation

## Latest publication

If you use the Open Targets Platform in your work, please cite our latest publication:

Buniello, A. et al. (2025). [Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery](https://academic.oup.com/nar/article/53/D1/D1467/7917960). _Nucleic Acids Research._

## Previous publications

We have additional publications about the Open Targets Platform:

* Ochoa, D. et al. (2023). [The next-generation Open Targets Platform: reimagined, redesigned, rebuilt.](https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac1046/6833237) _Nucleic Acids Research._
* Ochoa, D. et al. (2021). [Open Targets Platform: supporting systematic drug–target identification and prioritisation](https://doi.org/10.1093/nar/gkaa1027). _Nucleic Acids Research._
* Carvalho-Silva, D. et al. (2019). [Open Targets Platform: new developments and updates two years on](https://doi.org/10.1093/nar/gky1133). _Nucleic Acids Research_.
* Koscielny, G. et al. (2017). [Open Targets: a platform for therapeutic target identification and validation](https://doi.org/10.1093/nar/gkw1055). _Nucleic Acids Research._

You can also refer to our publications about Open Targets Genetics and our Locus-to-Gene (L2G) pipeline:

* Ghoussaini, M., et al. (2021) [Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics](https://doi.org/10.1093/nar/gkaa840). _Nucleic Acids Research_.
* Mountjoy, E., et al. (2021) [An open approach to systematically prioritize causal variants and genes at all published human GWAS trait-associated loci](https://doi.org/10.1038/s41588-021-00945-5). _Nature Genetics._

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