potjansdiesmann2014

Large scale model of cortical network from Potjans and Diesmann, 2014

https://github.com/opensourcebrain/potjansdiesmann2014

Science Score: 54.0%

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Large scale model of cortical network from Potjans and Diesmann, 2014

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  • Stars: 5
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  • Forks: 7
  • Open Issues: 5
  • Releases: 1
Created over 11 years ago · Last pushed 10 months ago
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README.md

Large scale model of cortical network from Potjans and Diesmann, 2014

Potjans and Diesmann (2014) describes a microcircuit model of early sensory cortex, displaying asynchronous irregular activity with layer-specific firing rates similar to the activity observed in cortex in the awake spontaneous condition. The inhibitory neurons have higher firing rates than the excitatory neurons, despite being modeled with identical intrinsic properties. Hence, this feature arises due to the connectivity of the network.

The model represents the approximately 80,000 neurons under a square mm of cortical surface, organized into layers 2/3, 4, 5, and 6. Each layer contains an excitatory and an inhibitory population of leaky integrate-and-fire neurons with current-based synapses, connected with delays. The population-specific connectivity and external Poisson inputs are based on the integration of anatomical and physiological data mainly from cat V1 and rat S1. The possibility is included of providing an additional thalamic stimulus to layers 4 and 6, which propagates across layers in a realistic fashion partly due to the target specificity of feedback projections across layers.

Raster and bar plots of spiking activity

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DOI

Reusing this model

The code in this repository is provided under the terms of the software license included with it. If you use this model in your research, we respectfully ask you to cite the references outlined in the CITATION file.

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  • Name: OpenSourceBrain
  • Login: OpenSourceBrain
  • Kind: organization

Citation (CITATION.md)

## Citing this model

The software in this repository is provided under the terms of the [software license](LICENSE) included with it. 

If you use this model in your research, we respectfully ask you to cite:

**The original publication upon which this model is based**

   - Potjans TC & Diesmann M (2014) The cell-type specific cortical microcircuit: relating structure and activity in a full-scale spiking network model. Cereb Cortex. 24(3):785-8062014.

**The latest release of this Open Source Brain repository**

   - This link should provide a DOI/citation for the latest version released: https://www.zenodo.org/badge/latestdoi/21612755. If you would like us to make a new release, please [open an issue](../../issues). 

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.github/workflows/omv-ci.yml actions
  • actions/checkout v2 composite
  • actions/setup-python v2 composite