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  • Owner: neuroconductor-devel
  • Language: R
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Metadata Files
Readme Citation

README.md

MNITemplate

The goal of MNITemplate is to provide the MNI Template of T1-weighted MRI imaging from http://www.bic.mni.mcgill.ca/ServicesAtlases/ICBM152NLin2009. In addition to the standard template, the image has been segmented into gray matter, white matter, and cerebrospinal fluid (’CSF’) using the ‘FAST’ algorithm from ‘FSL’ https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/FAST..

For a template with a full white-matter parcellation map, see our EveTemplate package.


Creator: Jean-Philippe Fortin, fortin946@gmail.com

Authors and Maintainers: Jean-Philippe Fortin, John Muschelli

Software status

| Resource: | Travis CI | | ----------- | ---------------------------------------------------------------------------------------------------------------------------------------------------- | | Platform: | Linux | | R CMD check | Build status |

Table of content

1. Introduction

The MNI152 template that is included with FSL: https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/Atlases

2. Reading the data into R

We first load the package into R: {r} library(MNITemplate)

Once the package is loaded into R, use the command readMNI() to import the MNI template T1-w image as a nifti object into R: {r} mni_t1 <- readMNI() One can use the function orthographic from the oro.nifti package to visualize the template: {r} orthographic(mni_t1)

In many preprocessing pipelines, the path of the template file in the system must be specified. For this, use the following: {r} mni_path <- getMNIPath() and to get brain mask: {r} mni_brain_mask_path <- getMNIPath("Brain_Mask")

3. Segmentation

We performed a 3-tissue class segmentation of the T1w MNI template using the FSL FAST segmentation algorithm via the fslr package. The script that was used to perform the segmentation can be found here. The segmentation labels are 0 for Background (outside of the brain), 1 for cerebrospinal fluid (CSF), 2 for grey matter (GM) and 3 for white matter (WM). Let's read the segmentation classes into R: {r} seg <- readMNISeg() orthographic(seg)

If one wishes to create a WM mask, could do the following: {r} wm_mask <- seg wm_mask[wm_mask!=3] <- 0 and similarly for the other tissues.

3. Files

| File | Description | Reader | | ---------------------------------------- | ------------------------------------------------------- | ---------------------------------- | | MNI152_TI_1mm.nii.gz | T1-w MNI Template, 1mm | readMNI("T1") | | MNI152_TI_1mm_Brain.nii.gz | T1-w MNI Template, 1mm, skull stripped | readMNI("Brain") | | MNI152_TI_1mm_Brain_Mask.nii.gz | T1-w MNI Template, 1mm, brain mask | readMNI("Brain_Mask") | | MNI152_TI_2mm.nii.gz | T1-w MNI Template, 2mm | readMNI("T1", res="2mm") | | MNI152_TI_2mm_Brain.nii.gz | T1-w MNI Template, 2mm, skull stripped | readMNI("Brain", res="2mm") | | MNI152_TI_2mm_Brain_Mask.nii.gz | T1-w MNI Template, 2mm, brain mask | readMNI("Brain_Mask", res="2mm") | | Tissue Segmentation: | | | | MNI152_TI_1mm_Brain_FAST_seg.nii.gz | FSL FAST tissue classes (1=CSF, 2=GM, 3=WM) for 1mm res | readMNISeg() | | MNI152_TI_2mm_Brain_FAST_seg.nii.gz | FSL FAST tissue classes (1=CSF, 2=GM, 3=WM) for 2mm res | readMNISeg(res="2mm") |

Owner

  • Name: Neuroconductor Development
  • Login: neuroconductor-devel
  • Kind: organization

Citation (CITATION.bib)

@article{fonov2011unbiased,
  title={Unbiased average age-appropriate atlases for pediatric studies},
  author={Fonov, Vladimir and Evans, Alan C and Botteron, Kelly and Almli, C Robert and McKinstry, Robert C and Collins, D Louis and Brain Development Cooperative Group and others},
  journal={NeuroImage},
  volume={54},
  number={1},
  pages={313--327},
  year={2011},
  publisher={Elsevier}
}

@article{fonov2009unbiased,
  title={Unbiased nonlinear average age-appropriate brain templates from birth to adulthood},
  author={Fonov, Vladimir S and Evans, Alan C and McKinstry, Robert C and Almli, CR and Collins, DL},
  journal={NeuroImage},
  volume={47},
  pages={S102},
  year={2009},
  publisher={Academic Press}
}

@inproceedings{collins1999animal,
  title={ANIMAL+ INSECT: improved cortical structure segmentation},
  author={Collins, D Louis and Zijdenbos, Alex P and Baar{\'e}, Wim FC and Evans, Alan C},
  booktitle={Biennial International Conference on Information Processing in Medical Imaging},
  pages={210--223},
  year={1999},
  organization={Springer}
}

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Dependencies

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.github/workflows/autoci_pkgdown.yml actions
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  • r-lib/actions/setup-pandoc v2 composite
  • r-lib/actions/setup-r v2 composite
DESCRIPTION cran
  • oro.nifti * imports
  • covr * suggests
  • testthat * suggests