gmentropy

calculate configurational entropy from a conformational ensemble

https://github.com/aszilagyi/gmentropy

Science Score: 41.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
    Found CITATION.cff file
  • codemeta.json file
  • .zenodo.json file
  • DOI references
    Found 4 DOI reference(s) in README
  • Academic publication links
    Links to: ncbi.nlm.nih.gov
  • Academic email domains
  • Institutional organization owner
  • JOSS paper metadata
  • Scientific vocabulary similarity
    Low similarity (8.5%) to scientific vocabulary

Keywords

command-line-tool entropy gaussian-mixture-models molecular-dynamics physics protein-structure python-application
Last synced: 6 months ago · JSON representation ·

Repository

calculate configurational entropy from a conformational ensemble

Basic Info
  • Host: GitHub
  • Owner: aszilagyi
  • License: gpl-3.0
  • Language: Python
  • Default Branch: master
  • Size: 49.8 KB
Statistics
  • Stars: 4
  • Watchers: 1
  • Forks: 1
  • Open Issues: 0
  • Releases: 0
Topics
command-line-tool entropy gaussian-mixture-models molecular-dynamics physics protein-structure python-application
Created almost 7 years ago · Last pushed about 5 years ago
Metadata Files
Readme License Citation

README.md

gmentro.py is a program to calculate configurational entropy from a conformational ensemble using Gaussian mixtures. It is an implementation of the algorithm described in

Gergely Gyimesi, Péter Závodszky, and András Szilágyi:\ Calculation of configurational entropy differences from conformational ensembles using Gaussian mixtures\ J. Chem. Theory Comput., 13(1):29-41. (2017)\ DOI: 10.1021/acs.jctc.6b00837 PubMed

If you use the program, please cite the above paper.

The program is written in Python (3.x recommended), and needs the numpy module. Much of the code has been adapted from Jakob Verbeek's Matlab code for accelerated Gaussian mixture learning.

As a documentation, a manual page is provided in gmentro.py.1.md, which is also available as a html file and a regular manpage file (copy this file into a directory in your MANPATH and you'll be able to use man gmentro.py to display the manual page).

xvg2dat.py is a helper program to create a torsion angle trajectory file from Gromacs coordinate trajectories. See instructions in the program file.

The Makefile only serves to create the various formats of the man page (requires the ronn program).

Owner

  • Name: András Szilágyi
  • Login: aszilagyi
  • Kind: user
  • Location: Budapest, Hungary
  • Company: Research Centre for Natural Sciences

Citation (CITATION.txt)

If you use this software and publish results, please cite:

Gergely Gyimesi, Péter Závodszky, and András Szilágyi:
Calculation of configurational entropy differences from conformational
ensembles using Gaussian mixtures.
J. Chem. Theory Comput., 13(1):29-41. (2017)
DOI: 10.1021/acs.jctc.6b00837 PubMed: 27958758

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