higlass

Fast, flexible and extensible genome browser.

https://github.com/higlass/higlass

Science Score: 77.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
    Found CITATION.cff file
  • codemeta.json file
    Found codemeta.json file
  • .zenodo.json file
    Found .zenodo.json file
  • DOI references
    Found 2 DOI reference(s) in README
  • Academic publication links
    Links to: zenodo.org
  • Committers with academic emails
    9 of 34 committers (26.5%) from academic institutions
  • Institutional organization owner
  • JOSS paper metadata
  • Scientific vocabulary similarity
    Low similarity (15.8%) to scientific vocabulary

Keywords

genomics hi-c hidivelab higlass visualization

Keywords from Contributors

bioinformatics imaging hubmap interactive single-cell zarr ome-tiff sparse ngs hdf5
Last synced: 4 months ago · JSON representation ·

Repository

Fast, flexible and extensible genome browser.

Basic Info
  • Host: GitHub
  • Owner: higlass
  • License: mit
  • Language: JavaScript
  • Default Branch: main
  • Homepage: http://higlass.io
  • Size: 154 MB
Statistics
  • Stars: 332
  • Watchers: 20
  • Forks: 52
  • Open Issues: 40
  • Releases: 234
Topics
genomics hi-c hidivelab higlass visualization
Created over 9 years ago · Last pushed 4 months ago
Metadata Files
Readme Changelog Contributing License Citation

README.md

Build Status Live Docs DOI Twitter Slack

Introduction

HiGlass is a web-based viewer for datasets too large to view at once. It features synchronized navigation of multiple views as well as continuous zooming and panning for navigation across genomic loci and resolutions. It supports visual comparison of genomic (e.g., Hi-C, ChIP-seq, or bed annotations) and other data (e.g., geographic maps, gigapixel images, or abstract 1D and 2D sequential data) from different experimental conditions and can be used to efficiently identify salient outcomes of experimental perturbations, generate new hypotheses, and share the results with the community.

A live instance can be found at https://higlass.io. A Docker container is available for running an instance locally, although we recommend using the higlass-manage package to start, stop and configure local instances.

For documentation about how to use and install HiGlass, please visit https://docs.higlass.io.

Citation

Kerpedjiev, P., Abdennur, N., Lekschas, F., McCallum, C., Dinkla, K., Strobelt, H., ... & Gehlenborg, N. HiGlass: Web-based Visual Exploration and Analysis of Genome Interaction Maps. Genome Biology (2018): 19:125. https://doi.org/10.1186/s13059-018-1486-1

Example

Development

To run higlass from its source code simply run the following:

npm clean-install // use --legacy-peer-deps if you get peer dependency errors npm start

This starts a server in development mode at http://localhost:5173/.

Warning The following examples need to be migrated to the latest build. Once started, a list of the examples can be found at http://localhost:8080/examples.html. Template viewconfs located at /docs/examples/viewconfs can viewed directly at urls such as http://localhost:8080/apis/svg.html?/viewconfs/overlay-tracks.json.

Tests

The tests for the React components and API functions are located in the test directory. Tests are run with vitest.

Useful commands:

  • Run all tests in the browser: npm test -- --browser.headless=false

See the contributing guide to learn more.

API

HiGlass provides an API for controlling the component from with JavaScript. Below is a minimal working example to get started and the complete documentation is availabe at docs.higlass.io.

```html <!DOCTYPE html> Minimal Working Example · HiGlass ```

Related

diagram of related tools

  • HiGlass Clodius - Package that provides implementations for aggregation and tile generation for many common 1D and 2D data types
  • HiGlass Python - Python bindings to the HiGlass for tile serving, view config generation, and Jupyter Notebook + Lab integration.
  • HiGlass Manage - Easy to use interface for deploying a local HiGlass instance
  • HiGlass Docker - Build an image containing all the components necessary to deploy HiGlass
  • HiGlass Server - Server component for serving multi-resolution data
  • HiGlass App - The code for the web application hosted at https://higlass.io
  • Cooler - Package for efficient storage of and access to sparse 2D data

License

HiGlass is provided under the MIT License.

Owner

  • Name: higlass
  • Login: higlass
  • Kind: organization

Multiscale big data visualization

Citation (CITATION.bib)

@article{kerpedjiev2018higlass,
  author = {Peter Kerpedjiev and Nezar Abdennur and Fritz Lekschas and Chuck McCallum and Kasper Dinkla and Hendrik Strobelt and Jacob M Luber and Scott B Ouellette and Alaleh Ahzir and Nikhil Kumar and Jeewon Hwang and Burak H Alver and Hanspeter Pfister and Leonid A Mirny and Peter J Park and Nils Gehlenborg},
  title = {HiGlass: Web-based Visual Exploration and Analysis of Genome Interaction Maps},
  journal = {Genome Biology},
  year = {2018},
  month = {8},
  day = {24},
  volume = {19},
  number = {1},
  pages = {125},
  doi = {10.1186/s13059-018-1486-1},
}

GitHub Events

Total
  • Issues event: 243
  • Watch event: 18
  • Delete event: 131
  • Issue comment event: 77
  • Push event: 387
  • Pull request review comment event: 86
  • Pull request review event: 83
  • Pull request event: 153
  • Fork event: 1
  • Create event: 80
Last Year
  • Issues event: 243
  • Watch event: 18
  • Delete event: 131
  • Issue comment event: 77
  • Push event: 387
  • Pull request review comment event: 86
  • Pull request review event: 83
  • Pull request event: 153
  • Fork event: 1
  • Create event: 80

Committers

Last synced: 7 months ago

All Time
  • Total Commits: 4,472
  • Total Committers: 34
  • Avg Commits per committer: 131.529
  • Development Distribution Score (DDS): 0.459
Past Year
  • Commits: 41
  • Committers: 4
  • Avg Commits per committer: 10.25
  • Development Distribution Score (DDS): 0.415
Top Committers
Name Email Commits
Peter Kerpedjiev p****v@g****m 2,421
Fritz Lekschas s****e@l****e 1,535
mccalluc m****c 166
Trevor Manz t****z@g****m 69
daniellenguyen d****7@g****m 67
Sehi L'Yi s****i@g****m 33
Alexander Veit 5****t 33
Kasper Dinkla k****a@g****m 30
Mark Keller 7****k 18
Alaleh Azhir A****r 17
Nils Gehlenborg n****s@h****u 16
Peter Kerpedjiev p****p@t****t 10
etowahadams e****s@g****m 10
Alex Reynolds a****s@g****m 8
Nezar Abdennur n****r@g****m 7
Clement Vachet c****t@s****u 4
Nikhil Kumar n****6@g****m 3
Alex Balashov a****v@h****u 3
Alaleh Azhir A****r@a****u 3
101arrowz a****t@g****m 2
Angela Chen c****0@u****u 2
Peter Kerpedjiev 4****n 2
dependabot[bot] 4****] 2
Alex Ostrovsky 4****1 1
Chadius t****s@g****m 1
Ilya Flyamer f****r@g****m 1
Peter p****r@d****u 1
Carl Vitzthum c****m@h****u 1
Alaleh Azhir A****r@a****u 1
Lmercadom 4****m 1
and 4 more...

Issues and Pull Requests

Last synced: 4 months ago

All Time
  • Total issues: 264
  • Total pull requests: 332
  • Average time to close issues: over 5 years
  • Average time to close pull requests: 10 months
  • Total issue authors: 87
  • Total pull request authors: 13
  • Average comments per issue: 1.63
  • Average comments per pull request: 1.03
  • Merged pull requests: 173
  • Bot issues: 0
  • Bot pull requests: 46
Past Year
  • Issues: 6
  • Pull requests: 132
  • Average time to close issues: about 4 hours
  • Average time to close pull requests: 3 days
  • Issue authors: 6
  • Pull request authors: 4
  • Average comments per issue: 0.5
  • Average comments per pull request: 0.23
  • Merged pull requests: 69
  • Bot issues: 0
  • Bot pull requests: 18
Top Authors
Issue Authors
  • flekschas (59)
  • mccalluc (39)
  • pkerpedjiev (34)
  • nvictus (12)
  • alexpreynolds (9)
  • rahmas36 (6)
  • manzt (5)
  • mimakaev (4)
  • sehilyi (4)
  • Phlya (3)
  • ngehlenborg (3)
  • keller-mark (3)
  • nandankita (2)
  • mildewey (2)
  • Chadius (2)
Pull Request Authors
  • manzt (133)
  • pkerpedjiev (70)
  • dependabot[bot] (46)
  • sehilyi (23)
  • keller-mark (16)
  • alexpreynolds (14)
  • alexander-veit (11)
  • flekschas (9)
  • etowahadams (8)
  • mccalluc (3)
  • nvictus (2)
  • wangqianwen0418 (1)
  • alexkb0009 (1)
Top Labels
Issue Labels
enhancement (62) bug (50) question (23) feature (16) technical debt (10) important (5) critical (4) good first issue (3) unclear (2) easy (2) documentation (2) 4DN (2) needs more info (2) v2 (1)
Pull Request Labels
dependencies (46) v2 (25) enhancement (17) bug (13) technical debt (11) javascript (8) testing (7) documentation (5) stalled (4) breaking change (3) security (1) release (1)

Packages

  • Total packages: 2
  • Total downloads:
    • npm 6,435 last-month
  • Total dependent packages: 46
    (may contain duplicates)
  • Total dependent repositories: 58
    (may contain duplicates)
  • Total versions: 253
  • Total maintainers: 2
npmjs.org: higlass

HiGlass Hi-C / genomic / large data viewer

  • Versions: 250
  • Dependent Packages: 45
  • Dependent Repositories: 57
  • Downloads: 6,225 Last month
Rankings
Dependent packages count: 0.6%
Dependent repos count: 1.8%
Average: 2.6%
Downloads: 2.9%
Stargazers count: 3.7%
Forks count: 4.1%
Maintainers (1)
Last synced: 4 months ago
npmjs.org: higlass-no-github-deps

HiGlass Hi-C / genomic / large data viewer

  • Versions: 3
  • Dependent Packages: 1
  • Dependent Repositories: 1
  • Downloads: 210 Last month
Rankings
Downloads: 3.4%
Stargazers count: 3.7%
Forks count: 4.1%
Average: 8.7%
Dependent repos count: 10.8%
Dependent packages count: 21.4%
Maintainers (1)
Last synced: 4 months ago

Dependencies

.github/workflows/ci.yml actions
  • actions/checkout v3 composite
  • actions/setup-node v3 composite
.github/workflows/docs.yml actions
  • actions/checkout v1 composite
  • actions/setup-node v2 composite
  • actions/setup-python v1 composite
  • jakejarvis/s3-sync-action master composite
.github/workflows/npmpublish.yml actions
  • actions/checkout v3 composite
  • actions/setup-node v3 composite