methylation-pipeline - Methylation-Pipeline v1.0.0 — First Public Release

This release includes the first stable version of the methylation-pipeline, a modular Python-based framework for filtering, analyzing, and visualizing CpG methylation data across patient cohorts and treatment timepoints.

Key features:

🔧 Preprocessing tools to filter methylation matrices by patient ID

📊 Global and locus-level methylation summary statistics

🧬 Timepoint classification (Baseline, On-Treatment, Post-Treatment, Healthy)

🧼 Built-in visualization of methylation trajectories and distributions

📁 Outputs ready for downstream statistical or clustering analyses

This pipeline is intended for researchers working with EM-Seq or cfDNA methylation data and can be adapted to other bisulfite-free methylation sequencing datasets.

For full documentation and usage examples, please see the README.

- Python
Published by codebyesther about 1 year ago