CircSeqAlignTk
An R package for end-to-end analysis of RNA-seq data for circular genome
Science Score: 49.0%
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Repository
An R package for end-to-end analysis of RNA-seq data for circular genome
Basic Info
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Metadata Files
README.md
CircSeqAlignTk
End-to-End Analysis of Small RNA-Seq Data from Viroids
CircSeqAlignTk is an end-to-end toolkit for RNA-Seq data analysis of circular genome sequences, supporting tasks from alignment to visualization. It is primarily designed for studying viroids, which are small, circular RNAs typically composed of a few hundred nucleotides. In addition to analysis capabilities, CircSeqAlignTk provides a streamlined interface for generating synthetic RNA-Seq data that closely mimics real datasets. This functionality enables developers to benchmark alignment tools, test novel alignment algorithms, and validate new workflows.
Installation
To install the CircSeqAlignTk package, start R (≥ 4.2) and run the following steps:
```{r install_package, eval=FALSE} if (!requireNamespace('BiocManager', quietly = TRUE)) install.packages('BiocManager')
BiocManager::install('CircSeqAlignTk') ```
Note that to install the latest version of the CircSeqAlignTk package, the latest version of R is required.
Documentation
Vignette, including overview of CircSeqAlignTk package, detailed explanation of functions, and several case studies, can be accessed with the following code.
browseVignettes('CircSeqAlignTk')
Citation
Sun J, Fu X and Cao W. CircSeqAlignTk: An R package for end-to-end analysis of RNA-seq data for circular genomes. F1000Research 2024, 11:1221. doi: 10.12688/f1000research.127348.2.
Owner
- Name: bitdessin
- Login: bitdessin
- Kind: organization
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- Profile: https://github.com/bitdessin
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Dependencies
- R >= 4.2 depends
- BiocGenerics * imports
- Biostrings * imports
- IRanges * imports
- Rbowtie2 * imports
- Rhisat2 * imports
- Rsamtools * imports
- S4Vectors * imports
- ShortRead * imports
- dplyr * imports
- ggplot2 * imports
- magrittr * imports
- methods * imports
- rlang * imports
- stats * imports
- tidyr * imports
- tools * imports
- utils * imports
- BiocStyle * suggests
- R.utils * suggests
- knitr * suggests
- rmarkdown * suggests
- testthat * suggests