haproh

Software to call ROHs

https://github.com/hringbauer/haproh

Science Score: 33.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
  • codemeta.json file
  • .zenodo.json file
  • DOI references
    Found 7 DOI reference(s) in README
  • Academic publication links
    Links to: biorxiv.org
  • Committers with academic emails
    6 of 9 committers (66.7%) from academic institutions
  • Institutional organization owner
  • JOSS paper metadata
  • Scientific vocabulary similarity
    Low similarity (12.9%) to scientific vocabulary
Last synced: 10 months ago · JSON representation

Repository

Software to call ROHs

Basic Info
  • Host: GitHub
  • Owner: hringbauer
  • License: gpl-3.0
  • Language: Jupyter Notebook
  • Default Branch: master
  • Size: 382 MB
Statistics
  • Stars: 16
  • Watchers: 2
  • Forks: 3
  • Open Issues: 2
  • Releases: 1
Created over 7 years ago · Last pushed over 1 year ago
Metadata Files
Readme License

README.md

Development github repository for the software hapROH and hapCON

Harald Ringbauer, Yilei Huang, May 2022; Code released under GNU General Public License v3.0

This is the code repository intended for contributing developers (i.e. to manage code used in development and publications). The release for users is made available as an installable Python software package hapROH. The official user documentation is available at readthedocs. It contains quick-start guides as well as usage examples on test data.

There are three main parts of the hapROH package:

hapROH

Software to call ROH from ancient and present-day DNA using reference haplotypes. Author: Harald Ringbauer, September 2020 Code released under GNU General Public License v3.0

Development Code behind python package hapROH. Please refer to our online documentation for details about the current version and installation.

This is the git repository for development, as well as code used in the hapROH publication.

hapCon

hapCon is an extension of hapROH for estimaing contamination rate for male aDNA samples.

We have prepared a detailed online documentation for hapCon. In addition, a jupyter notebook guide for using our method is availble at ./Notebooks/Vignettes/hapCon_vignette.ipynb in this repository. We also have a preprint for hapCon if you are interested in more technical details and its usage limits.

hapROH with Contamination

Joint estimation of ROH blocks and Contamination Rate

Please refer to our readthedocs site for details.

Installation

You only need to install the PyPi package hapROH to use both hapCon and hapROH:

To install via pip:

pip install hapROH

To upgrade an existing installation:

pip install --upgrade hapROH

References

Scientific manuscripts introducing the methods are available at: - https://doi.org/10.1038/s41467-021-25289-w for hapROH - https://doi.org/10.1101/2021.12.20.473429 for hapCon

Owner

  • Name: Harald Ringbauer
  • Login: hringbauer
  • Kind: user
  • Location: Leipzig
  • Company: Max Planck Institute for Evolutionary Anthropology

Creating methods in computational population genetics. Focus on ancient DNA analysis. Group Leader @ Max Planck Institute, Archaeogenetics Department, Leipzig

GitHub Events

Total
  • Issues event: 4
  • Watch event: 2
  • Issue comment event: 5
  • Push event: 6
  • Pull request event: 2
Last Year
  • Issues event: 4
  • Watch event: 2
  • Issue comment event: 5
  • Push event: 6
  • Pull request event: 2

Committers

Last synced: over 2 years ago

All Time
  • Total Commits: 575
  • Total Committers: 9
  • Avg Commits per committer: 63.889
  • Development Distribution Score (DDS): 0.555
Past Year
  • Commits: 13
  • Committers: 3
  • Avg Commits per committer: 4.333
  • Development Distribution Score (DDS): 0.538
Top Committers
Name Email Commits
hringbauer h****r@u****u 256
hyl317 y****2@c****u 143
Harald Ringbauer h****r@g****t 139
Harald Ringbauer h****r@h****u 26
steinrue s****e@u****u 7
Harald Ringbauer h****r@i****t 1
Harald Ringbauer h****r@m****l 1
Yilei Huang h****l@Y****l 1
Ringbauer h****7@l****u 1
Committer Domains (Top 20 + Academic)

Issues and Pull Requests

Last synced: 11 months ago

All Time
  • Total issues: 10
  • Total pull requests: 7
  • Average time to close issues: about 1 month
  • Average time to close pull requests: about 4 hours
  • Total issue authors: 8
  • Total pull request authors: 1
  • Average comments per issue: 2.5
  • Average comments per pull request: 0.0
  • Merged pull requests: 7
  • Bot issues: 0
  • Bot pull requests: 0
Past Year
  • Issues: 3
  • Pull requests: 1
  • Average time to close issues: about 1 month
  • Average time to close pull requests: 1 minute
  • Issue authors: 3
  • Pull request authors: 1
  • Average comments per issue: 1.67
  • Average comments per pull request: 0.0
  • Merged pull requests: 1
  • Bot issues: 0
  • Bot pull requests: 0
Top Authors
Issue Authors
  • ryhui (2)
  • eshab5 (2)
  • pur80a (1)
  • mariamnawaz1 (1)
  • ngaens (1)
  • TCLamnidis (1)
  • jkimsis (1)
  • batelz (1)
Pull Request Authors
  • hringbauer (8)
Top Labels
Issue Labels
Pull Request Labels

Packages

  • Total packages: 1
  • Total downloads:
    • pypi 68 last-month
  • Total dependent packages: 0
  • Total dependent repositories: 1
  • Total versions: 27
  • Total maintainers: 1
pypi.org: haproh

Identify runs of homozygosity (hapROH) and contamination (hapCon) in low coverage ancient human DNA data (1240K SNPs) using modern reference panel

  • Versions: 27
  • Dependent Packages: 0
  • Dependent Repositories: 1
  • Downloads: 68 Last month
Rankings
Dependent packages count: 10.0%
Forks count: 16.8%
Stargazers count: 17.7%
Average: 18.5%
Dependent repos count: 21.7%
Downloads: 26.3%
Maintainers (1)
Last synced: 11 months ago

Dependencies

docs/requirements.txt pypi
  • sphinx *
  • sphinx-autoapi *
  • sphinx_rtd_theme *
package/setup.py pypi
  • cython *
  • h5py *
  • matplotlib *
  • numdifftools *
  • numpy *
  • pandas *
  • psutil *
  • pysam *
  • scipy *