pyorganoidnet

This repository provides StarDist and CellPose models, meticulously trained on a large dataset of Pancreatic Ductal Adenocarcinoma organoids co-cultured with immune cells. Pre-print available at https://www.biorxiv.org/content/10.1101/2024.02.12.580032v1. Demo application available at https://segmentorganoids.streamlit.app/

https://github.com/ajinkya-kulkarni/pyorganoidnet

Science Score: 67.0%

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    Low similarity (9.2%) to scientific vocabulary

Keywords

cellpose deep-learning organoid-segmentation organoids stardist
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Repository

This repository provides StarDist and CellPose models, meticulously trained on a large dataset of Pancreatic Ductal Adenocarcinoma organoids co-cultured with immune cells. Pre-print available at https://www.biorxiv.org/content/10.1101/2024.02.12.580032v1. Demo application available at https://segmentorganoids.streamlit.app/

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cellpose deep-learning organoid-segmentation organoids stardist
Created over 2 years ago · Last pushed over 1 year ago
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Readme License Citation

README.md

Streamlit App License: GPL v3 DOI GitHub commit activity GitHub release (latest by date)

OrganoIDNetData: Pancreatic Ductal Adenocarcinoma Organoid Dataset

Introduction

Welcome to the OrganoIDNetData repository. This public dataset is a significant step forward in cancer research, particularly in the study of Pancreatic Ductal Adenocarcinoma (PDAC). It comprises phase-contrast images of murine and patient-derived tumor organoids co-cultured with immune cells. With 190 images and 33,906 organoids, OrganoIDNetData serves as a potential benchmark for organoid segmentation models in oncological research. The pre-print based on this work can be found here.

Dataset Overview

  • Type of Cancer: Pancreatic Ductal Adenocarcinoma
  • Images: 190 phase-contrast images
  • Organoids Count: 33,906
  • Culturing: Co-cultured with immune cells
  • Focus: Tumor organoids

Objective

The primary objective of OrganoIDNetData is to address the challenges in organoid research, particularly: - Efficient and reliable segmentation of organoid images - Quantification of organoid growth, regression, and response to treatments - Prediction of organoid system behaviors

Usage

This dataset is intended for use in developing and testing algorithms for: - Object detection and segmentation in organoid images - Machine learning models in oncology research - Benchmarking against other organoid segmentation models

Contributing

We welcome contributions to OrganoIDNetData! If you have suggestions or improvements, please fork the repository and submit a pull request.

Owner

  • Name: Ajinkya Kulkarni
  • Login: ajinkya-kulkarni
  • Kind: user
  • Location: Göttingen
  • Company: Max Planck Institute for Multidisciplinary Sciences

Image Data Scientist @mpi_nat working in Translational Oncology

Citation (CITATION.cff)

cff-version: 1.2.0
message: "If you use this software, please cite it as below."
authors:
- family-names: "Kulkarni"
  given-names: "Ajinkya"
  orcid: "https://orcid.org/0000-0003-1423-3676"
title: "PyOrganoIDNet"
version: 1.0
doi: 10.5281/zenodo.10630731
date-released: 2024-02-07
url: "https://github.com/ajinkya-kulkarni/PyOrganoIDNet"

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