Chi

Chi: A Python package for treatment response modelling - Published in JOSS (2024)

https://github.com/davaug/chi

Science Score: 98.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
    Found CITATION.cff file
  • codemeta.json file
    Found codemeta.json file
  • .zenodo.json file
    Found .zenodo.json file
  • DOI references
    Found 9 DOI reference(s) in README and JOSS metadata
  • Academic publication links
    Links to: joss.theoj.org
  • Committers with academic emails
  • Institutional organization owner
  • JOSS paper metadata
    Published in Journal of Open Source Software

Keywords

bayesian-inference mipd model-informed-precision-dosing parameter-estimation pharmacodynamics pharmacokinetics pkpd pkpd-modelling python

Scientific Fields

Earth and Environmental Sciences Physical Sciences - 62% confidence
Last synced: 4 months ago · JSON representation ·

Repository

Chi is an open source Python package which is designed for PKPD modelling and model-informed precision dosing (MIPD).

Basic Info
Statistics
  • Stars: 10
  • Watchers: 1
  • Forks: 5
  • Open Issues: 34
  • Releases: 7
Topics
bayesian-inference mipd model-informed-precision-dosing parameter-estimation pharmacodynamics pharmacokinetics pkpd pkpd-modelling python
Created about 5 years ago · Last pushed over 1 year ago
Metadata Files
Readme Contributing License Citation

README.md

Chi

Unit tests on multiple python versions Unit tests on multiple operating systems codecov Documentation Status DOI

About

Chi is an open source Python package for pharmacokinetic and pharmacodynamic (PKPD) modelling.

All features of the software are described in detail in the full API documentation.

Getting started

Installation

  1. Install sundials

Chi uses the open source package Myokit to solve ordinary differential equations and compute their sensitivities efficiently. Myokit does this using sundials' CVODESS, which needs to be installed with:

  • On Ubuntu: bash apt-get install libsundials-dev

  • On MacOS: bash brew install sundials

  • On Windows: No action required. Myokit will install sundial automatically.

  1. Install chi bash pip install chi-drm

You can now use chi's functionality by importing it python import chi

### Tutorials

Tutorials and more detailed explanations on how to use chi can be found in the documentation's getting started section.

Citation

If you use this software in your work, please cite it using the following metadata:

Citation string

Augustin, D., (2024). Chi: A Python package for treatment response modelling. Journal of Open Source Software, 9(94), 5925, https://doi.org/10.21105/joss.05925

BibTeX

@article{ Augustin2024, doi = {10.21105/joss.05925}, url = {https://doi.org/10.21105/joss.05925}, year = {2024}, publisher = {The Open Journal}, volume = {9}, number = {94}, pages = {5925}, author = {David Augustin}, title = {Chi: A Python package for treatment response modelling}, journal = {Journal of Open Source Software} }

Contributing

There are lots of ways how you can contribute to Chi's development, and you are welcome to join in! For example, you can report problems or make feature requests on the issues pages.

Similarly, if you would like to contribute documentation or code you can create and issue, and then provide a pull request for review. To facilitate contributions, we have written extensive contribution guidelines to help you navigate the code.

License

BSD-3-Clause

Owner

  • Name: David Augustin
  • Login: DavAug
  • Kind: user

DPhil in Computer Science at the University of Oxford.

JOSS Publication

Chi: A Python package for treatment response modelling
Published
February 07, 2024
Volume 9, Issue 94, Page 5925
Authors
David Augustin ORCID
Department of Computer Science, University of Oxford, Oxford, United Kingdom
Editor
Antonia Mey ORCID
Tags
pkpd treatment planning inference Bayesian inference

Citation (CITATION.cff)

cff-version: 1.0.0
message: "If you use this software, please cite it as below."
authors:
- family-names: "Augustin"
  given-names: "David"
  orcid: "https://orcid.org/0000-0002-4885-1088"
title: "Chi: A Python package for treatment response modelling"
version: 1.0.0
year: 2024
url: "https://github.com/DavAug/chi"
preferred-citation:
  type: article
  authors:
  - family-names: "Augustin"
    given-names: "David"
    orcid: "https://orcid.org/0000-0002-4885-1088"
  title: "Chi: A Python package for treatment response modelling"
  version: 1.0.0
  year: 2024
  url: "https://doi.org/10.21105/joss.05925"
  doi: "10.21105/joss.05925"
  publisher: "The Open Journal"
  journal: "Journal of Open Source Software"
  volume: 9
  number: 94
  pages: 5925

GitHub Events

Total
  • Watch event: 3
Last Year
  • Watch event: 3

Committers

Last synced: 9 months ago

All Time
  • Total Commits: 1,698
  • Total Committers: 1
  • Avg Commits per committer: 1,698.0
  • Development Distribution Score (DDS): 0.0
Past Year
  • Commits: 7
  • Committers: 1
  • Avg Commits per committer: 7.0
  • Development Distribution Score (DDS): 0.0
Top Committers
Name Email Commits
DavAug d****n@g****t 1,698
Committer Domains (Top 20 + Academic)
gmx.net: 1

Issues and Pull Requests

Last synced: 4 months ago

All Time
  • Total issues: 70
  • Total pull requests: 46
  • Average time to close issues: about 2 months
  • Average time to close pull requests: about 1 month
  • Total issue authors: 3
  • Total pull request authors: 3
  • Average comments per issue: 0.16
  • Average comments per pull request: 0.96
  • Merged pull requests: 43
  • Bot issues: 0
  • Bot pull requests: 0
Past Year
  • Issues: 1
  • Pull requests: 0
  • Average time to close issues: N/A
  • Average time to close pull requests: N/A
  • Issue authors: 1
  • Pull request authors: 0
  • Average comments per issue: 0.0
  • Average comments per pull request: 0
  • Merged pull requests: 0
  • Bot issues: 0
  • Bot pull requests: 0
Top Authors
Issue Authors
  • DavAug (68)
  • ns-rse (1)
  • breisfeld (1)
Pull Request Authors
  • DavAug (46)
  • MichaelClerx (1)
  • martinjrobins (1)
Top Labels
Issue Labels
Pull Request Labels

Dependencies

docs/requirements.txt pypi
  • kaleido *
  • sphinx >=1.5,
  • sphinx-rtd-theme *
setup.py pypi
  • arviz >=0.11
  • myokit >=1.33
  • numpy >=1.17
  • pandas >=0.24
  • pints >=0.4
  • plotly >=4.8.1
  • tqdm >=4.46.1
  • xarray >=0.19
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