Science Score: 67.0%
This score indicates how likely this project is to be science-related based on various indicators:
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✓CITATION.cff file
Found CITATION.cff file -
✓codemeta.json file
Found codemeta.json file -
✓.zenodo.json file
Found .zenodo.json file -
✓DOI references
Found 5 DOI reference(s) in README -
✓Academic publication links
Links to: zenodo.org -
○Committers with academic emails
-
○Institutional organization owner
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○JOSS paper metadata
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○Scientific vocabulary similarity
Low similarity (13.7%) to scientific vocabulary
Keywords
Keywords from Contributors
Repository
A high-performance BigWig and BigBed library in Rust
Basic Info
Statistics
- Stars: 101
- Watchers: 3
- Forks: 8
- Open Issues: 16
- Releases: 25
Topics
Metadata Files
README.md
Bigtools 
| Rust, CLI |
|
| Python |
|
Bigtools is a library and associated tools for reading and writing bigwig and bigbed files.
The primary goals of the project are to be - Performant - Extensible - Modern
Performant
Bigtools uses async/await internally to allow for efficient, multi-core computation when possible. In addition, tools are optimized for minimal memory usage. See Benchmarks for more details.
Extensible
Bigtools is designed to be as modular as possible. This, in addition to the safety and reliability of Rust, allows both flexibility and correctness as a library. In addition, its extremely easy to quickly create new tools or binaries. A number of binaries are available that parallel related existing binaries from UCSC, with drop-in compatibility for the most common flags.
Modern
Bigtools is written in Rust and published to crates.io, so binaries can be installed with cargo install bigtools or it can be used as a library by simply including it in your cargo.toml.
Library
To use bigtools in your Rust project, add bigtools to your Cargo.toml or run:
sh
cargo add bigtools
See the bigtools 🦀 Documentation.
Example
```rust,norun use bigtools::bbiread::BigWigRead;
let mut reader = BigWigRead::open("test.bigWig").unwrap(); let chr1 = reader.get_interval("chr1", 0, 10000).unwrap(); for interval in chr1 { println!("{:?}", interval); } ```
Binaries
The bigtools CLI binaries can be installed through crates.io or conda.
sh
cargo install bigtools
sh
conda install -c bioconda bigtools
Additionally, pre-built binaries can be downloaded through Github releases.
The following binaries are available:
|binary|description| | ---- | ----- | |bigtools|Provides access to multiple subcommands, including all below| |bedgraphtobigwig|Writes a bigWig from a given bedGraph file| |bedtobigbed|Writes a bigBed from a given bed file| |bigbedinfo|Shows info about a provided bigBed| |bigbedtobed|Writes a bed from the data in a bigBed| |bigwigaverageoverbed|Calculate statistics over the regions of a bed file using values from a bigWig| |bigwiginfo|Shows info about a provided bigWig| |bigwigmerge|Merges multiple bigWigs, outputting to either a new bigWig or a bedGraph| |bigwigtobedgraph|Writes a bedGraph from the data in a bigWig| |bigwigvaluesoverbed|Get the per-base values from a bigWig over the regions of a bed file using values|
Renaming the bigtools binary to any of the subcommands (case-insensitive) allows you to run that subcommand directly.
Python wrapper
The pybigtools package is a Python wrapper written using PyO3. It can be installed or used as a dependency either through PyPI or conda.
sh
pip install pybigtools
sh
conda install -c bioconda pybigtools
See the pybigtools 🐍 API Documentation.
How to build from source
In order to build the bigtools binaries, you can run
cargo build --release
and the binaries can be found in target/release/.
Otherwise, you can install the binaries from source by running
cargo install --path bigtools/
Building the python wheels for pybigtools requires maturin. To build the pybigtools wheel for installation (and install), you can run
maturin build --release -m pybigtools/Cargo.toml
pip install target/wheels/pybigtools*.whl
or
maturin develop --release -m pybigtools/Cargo.toml
Benchmarks
Benchmarks are included in the ./bench directory. They require python to run.
Multiple tools are compared against the comparable UCSC tools. For completeness, both single-threaded and multi-threaded (when available) benchmarks are included. Multiple different configuration options are benchmarked across multiple replicates, but a summar is available in the table below:

How to cite
This repository contains contains a CITATION.cff file with citation information. Github allows you to get a citation in either APA or BibTeX format; this is available in "Cite this repository" under About.
Owner
- Name: Jack Huey
- Login: jackh726
- Kind: user
- Repositories: 23
- Profile: https://github.com/jackh726
Citation (CITATION.cff)
cff-version: 1.2.0
type: software
title: Bigtools
license: MIT
repository-code: 'https://github.com/jackh726/bigtools'
message: >-
If you use this software, please cite it using the
metadata from this file.
authors:
- given-names: Jack
family-names: Huey
orcid: "https://orcid.org/0000-0003-3463-7192"
abstract: >-
Bigtools is a performant, extensible, and modern library for reading and writing BigWig and BigBed genomic data files, written in Rust. It also includes executable binaries for the command line as well as Python bindings.
keywords:
- bigwig
- bigbed
- bbi
- bioinformatics
- genomics
- kent
- ucsc
- rust
- python
identifiers:
- type: doi
value: 10.5281/zenodo.10606493
description: Zenodo
- type: doi
value: 10.1101/2024.02.06.579187
description: bioRxiv preprint
- type: doi
value: 10.1093/bioinformatics/btae350
description: Publication
preferred-citation:
type: article
title: "Bigtools: a high-performance BigWig and BigBed library in Rust"
authors:
- given-names: Jack
family-names: Huey
orcid: "https://orcid.org/0000-0003-3463-7192"
- given-names: Nezar
family-names: Abdennur
orcid: "https://orcid.org/0000-0001-5814-0864"
journal: Bioinformatics
year: 2024
doi: "10.1093/bioinformatics/btae350"
url: https://doi.org/10.1093/bioinformatics/btae350
GitHub Events
Total
- Create event: 10
- Release event: 10
- Issues event: 41
- Watch event: 26
- Delete event: 2
- Issue comment event: 126
- Push event: 50
- Pull request review comment event: 1
- Pull request review event: 4
- Pull request event: 17
- Fork event: 3
Last Year
- Create event: 10
- Release event: 10
- Issues event: 41
- Watch event: 26
- Delete event: 2
- Issue comment event: 126
- Push event: 50
- Pull request review comment event: 1
- Pull request review event: 4
- Pull request event: 17
- Fork event: 3
Committers
Last synced: 9 months ago
Top Committers
| Name | Commits | |
|---|---|---|
| Jack Huey | 3****6 | 496 |
| Nezar Abdennur | n****r@g****m | 39 |
| Gert Hulselmans | g****s@k****e | 9 |
| Donald Campbell | 1****r | 3 |
| dependabot[bot] | 4****] | 1 |
| Peter Kerpedjiev | p****v@g****m | 1 |
| Anders Pitman | t****1@g****m | 1 |
Committer Domains (Top 20 + Academic)
Issues and Pull Requests
Last synced: 6 months ago
All Time
- Total issues: 41
- Total pull requests: 43
- Average time to close issues: 3 months
- Average time to close pull requests: 1 day
- Total issue authors: 18
- Total pull request authors: 9
- Average comments per issue: 2.93
- Average comments per pull request: 1.16
- Merged pull requests: 36
- Bot issues: 0
- Bot pull requests: 1
Past Year
- Issues: 25
- Pull requests: 13
- Average time to close issues: 28 days
- Average time to close pull requests: about 19 hours
- Issue authors: 15
- Pull request authors: 4
- Average comments per issue: 2.24
- Average comments per pull request: 1.0
- Merged pull requests: 9
- Bot issues: 0
- Bot pull requests: 0
Top Authors
Issue Authors
- ghuls (10)
- jackh726 (6)
- mrvollger (4)
- donaldcampbelljr (3)
- nvictus (3)
- sergpolly (2)
- stela2502 (2)
- pkerpedjiev (1)
- mtvector (1)
- casblaauw (1)
- nleroy917 (1)
- maxgmarin (1)
- dmalzl (1)
- ypauling (1)
- khoroshevskyi (1)
Pull Request Authors
- nvictus (40)
- ghuls (16)
- jackh726 (4)
- nleroy917 (2)
- anderspitman (2)
- donaldcampbelljr (1)
- pkerpedjiev (1)
- paul-sud (1)
- dependabot[bot] (1)
Top Labels
Issue Labels
Pull Request Labels
Packages
- Total packages: 2
-
Total downloads:
- cargo 78,383 total
- pypi 2,197 last-month
-
Total dependent packages: 5
(may contain duplicates) -
Total dependent repositories: 1
(may contain duplicates) - Total versions: 40
- Total maintainers: 2
crates.io: bigtools
A library and associated tools for reading and writing bigwigs and bigbeds
- Documentation: https://docs.rs/bigtools/
- License: MIT
-
Latest release: 0.5.6
published 11 months ago
Rankings
Maintainers (1)
pypi.org: pybigtools
Python bindings to the Bigtools Rust library for high-performance BigWig and BigBed I/O
- Documentation: https://pybigtools.readthedocs.io/
- License: MIT
-
Latest release: 0.2.4
published about 1 year ago
Rankings
Maintainers (1)
Dependencies
- actions-rs/toolchain v1 composite
- actions/checkout v2 composite
- actions/checkout v2 composite
- papeloto/action-zip v1 composite
- shogo82148/actions-upload-release-asset v1 composite
- 131 dependencies
- rand 0.8 development
- attohttpc 0.25
- bincode 1.3
- byteorder 1
- byteordered 0.6.0
- bytes 1.4.0
- clap 3.2.0
- crossbeam-channel 0.5
- crossbeam-utils 0.8
- futures 0.3.28
- itertools 0.10
- libdeflater 0.13
- parking_lot 0.12.1
- ryu 1.0
- serde 1
- tempfile 3
- thiserror 1
- ufmt 0.2
- rand 0.8 development
- attohttpc 0.25
- bincode 1.3
- byteorder 1
- byteordered 0.6.0
- bytes 1.4.0
- clap 4.3
- crossbeam-channel 0.5
- crossbeam-utils 0.8
- futures 0.3.28
- itertools 0.10
- libdeflater 0.13
- ryu 1.0
- serde 1
- smallvec 1.11.2
- tempfile 3
- thiserror 1
- tokio 1.34.0
- ufmt 0.2
- 151 dependencies
- python 3.8.6 build
- rust buster build
- numpy *
- PyO3/maturin-action v1 composite
- actions/checkout v3 composite
- actions/download-artifact v3 composite
- actions/setup-python v4 composite
- actions/upload-artifact v3 composite