GeoDiff

GeoDiff, an R package for count generating models for analyzing Geomx RNA data. Note that this version of the package is still under development, undergoing submission process to Bioconductor 3.14 release and still needs to complete NanoString internal verification process.

https://github.com/nanostring-biostats/geodiff

Science Score: 13.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
  • codemeta.json file
    Found codemeta.json file
  • .zenodo.json file
  • DOI references
  • Academic publication links
  • Committers with academic emails
  • Institutional organization owner
  • JOSS paper metadata
  • Scientific vocabulary similarity
    Low similarity (8.5%) to scientific vocabulary
Last synced: 11 months ago · JSON representation

Repository

GeoDiff, an R package for count generating models for analyzing Geomx RNA data. Note that this version of the package is still under development, undergoing submission process to Bioconductor 3.14 release and still needs to complete NanoString internal verification process.

Basic Info
  • Host: GitHub
  • Owner: Nanostring-Biostats
  • License: mit
  • Language: R
  • Default Branch: main
  • Homepage:
  • Size: 10.1 MB
Statistics
  • Stars: 8
  • Watchers: 5
  • Forks: 6
  • Open Issues: 8
  • Releases: 1
Created almost 5 years ago · Last pushed about 1 year ago
Metadata Files
Readme Changelog License

README.md

GeoDiff

Overview

We present GeoDiff, an R package for count generating models for analyzing Geomx RNA data, demonstrated by example data analysis pipeline vignette. The package provides a series of statistical models using count generating distributions for fundamental tasks including background modelling, target and sample QC, normalization and differential expression analysis. The new methods are shown to be more suitable for these tasks in real examples than some conventional methods.

It contains the definition of the NanoStringGeoMxSet class which inherits from Biobase’s ExpressionSet class and NanoStringRCCSet class.

Installation

Install the development version from GitHub

r install.packages("devtools") library("devtools") devtools::install_github("Nanostring-Biostats/GeoDiff", ref = "dev")

License

This project is licensed under the MIT license.

Owner

  • Name: NanoString Technologies, Inc.
  • Login: Nanostring-Biostats
  • Kind: organization
  • Email: support@nanostring.com

GitHub Events

Total
  • Issues event: 1
  • Watch event: 1
  • Issue comment event: 1
  • Push event: 1
Last Year
  • Issues event: 1
  • Watch event: 1
  • Issue comment event: 1
  • Push event: 1

Committers

Last synced: almost 3 years ago

All Time
  • Total Commits: 73
  • Total Committers: 8
  • Avg Commits per committer: 9.125
  • Development Distribution Score (DDS): 0.726
Past Year
  • Commits: 0
  • Committers: 0
  • Avg Commits per committer: 0.0
  • Development Distribution Score (DDS): 0.0
Top Committers
Name Email Commits
Zhi Yang z****g@n****m 20
Lei Yang l****g@n****m 16
zhiiiyang z****5@g****m 13
Maddy Griswold 4****z 7
Nicole Ortogero n****o@n****m 7
NicoleEO N****o@g****m 6
Nitesh Turaga n****a@g****m 2
maddygriz m****d@n****m 2
Committer Domains (Top 20 + Academic)

Packages

  • Total packages: 1
  • Total downloads:
    • bioconductor 7,620 total
  • Total dependent packages: 0
  • Total dependent repositories: 0
  • Total versions: 5
  • Total maintainers: 1
bioconductor.org: GeoDiff

Count model based differential expression and normalization on GeoMx RNA data

  • Versions: 5
  • Dependent Packages: 0
  • Dependent Repositories: 0
  • Downloads: 7,620 Total
Rankings
Dependent repos count: 0.0%
Dependent packages count: 0.0%
Average: 27.3%
Downloads: 81.9%
Maintainers (1)
Last synced: about 1 year ago

Dependencies

DESCRIPTION cran
  • Biobase * depends
  • R >= 4.1.0 depends
  • GeomxTools * imports
  • Matrix * imports
  • NanoStringNCTools * imports
  • Rcpp >= 1.0.4.6 imports
  • graphics * imports
  • lme4 * imports
  • methods * imports
  • plyr * imports
  • robust * imports
  • stats * imports
  • testthat * imports
  • withr * imports
  • dplyr * suggests
  • knitr * suggests
  • rmarkdown * suggests
.github/workflows/main.yml actions
  • EddieHubCommunity/gh-action-community/src/welcome main composite