screenCounter

Get barcode counts from functional genomics screens

https://github.com/crisprverse/screencounter

Science Score: 13.0%

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    Low similarity (7.5%) to scientific vocabulary

Keywords from Contributors

bioconductor-package grna-sequence bioconductor
Last synced: 11 months ago · JSON representation

Repository

Get barcode counts from functional genomics screens

Basic Info
Statistics
  • Stars: 3
  • Watchers: 2
  • Forks: 0
  • Open Issues: 1
  • Releases: 0
Created over 3 years ago · Last pushed over 1 year ago
Metadata Files
Readme License

README.md

Counting barcodes in functional screens

|Environment|Status| |---|---| |BioC-release|Release OK| |BioC-devel|Devel OK|

screenCounter quantifies the frequency of barcodes in sequencing data from functional screens, yielding a count matrix that can be subjected to further statistical analyses, e.g., with edgeR and contemporaries. We support single barcode, combinatorial barcode and dual barcode designs, where each construct is assumed to have constant sequence(s) flanking one or more variable regions of known length. The package also provides options for mismatches, strand-specific searching and parallelization via BiocParallel.

For users: check out the documentation at the Bioconductor landing page for installation and usage instructions.

For developers: this R package is just a wrapper around the kaori C++ library that does the heavy lifting. Pull requests for new barcode designs should be made in kaori first, and then propagated back down to screenCounter.

Owner

  • Name: crisprVerse
  • Login: crisprVerse
  • Kind: organization
  • Email: fortin946@gmail.com

Bioconductor ecosystem for CRISPR gRNA design

GitHub Events

Total
  • Push event: 1
  • Fork event: 1
  • Create event: 1
Last Year
  • Push event: 1
  • Fork event: 1
  • Create event: 1

Committers

Last synced: almost 3 years ago

All Time
  • Total Commits: 318
  • Total Committers: 6
  • Avg Commits per committer: 53.0
  • Development Distribution Score (DDS): 0.11
Past Year
  • Commits: 30
  • Committers: 3
  • Avg Commits per committer: 10.0
  • Development Distribution Score (DDS): 0.133
Top Committers
Name Email Commits
Aaron Lun l****n@g****m 283
LTLA i****s@g****m 26
fortinj2 f****e@g****m 5
J Wokaty j****y 2
Jean-Philippe Fortin - Regular f****2@n****m 1
fortinj2 f****2@g****m 1
Committer Domains (Top 20 + Academic)

Issues and Pull Requests

Last synced: almost 2 years ago

All Time
  • Total issues: 4
  • Total pull requests: 2
  • Average time to close issues: 2 days
  • Average time to close pull requests: 1 day
  • Total issue authors: 2
  • Total pull request authors: 1
  • Average comments per issue: 3.5
  • Average comments per pull request: 0.0
  • Merged pull requests: 2
  • Bot issues: 0
  • Bot pull requests: 0
Past Year
  • Issues: 1
  • Pull requests: 0
  • Average time to close issues: 1 day
  • Average time to close pull requests: N/A
  • Issue authors: 1
  • Pull request authors: 0
  • Average comments per issue: 6.0
  • Average comments per pull request: 0
  • Merged pull requests: 0
  • Bot issues: 0
  • Bot pull requests: 0
Top Authors
Issue Authors
  • j-andrews7 (3)
  • williambakhache (1)
Pull Request Authors
  • LTLA (2)
Top Labels
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Packages

  • Total packages: 1
  • Total downloads:
    • bioconductor 4,861 total
  • Total dependent packages: 0
  • Total dependent repositories: 0
  • Total versions: 5
  • Total maintainers: 1
bioconductor.org: screenCounter

Counting Reads in High-Throughput Sequencing Screens

  • Versions: 5
  • Dependent Packages: 0
  • Dependent Repositories: 0
  • Downloads: 4,861 Total
Rankings
Dependent repos count: 0.0%
Dependent packages count: 0.0%
Average: 33.2%
Downloads: 99.6%
Last synced: 11 months ago