sRACIPE

sRACIPE for bioconductor

https://github.com/vivekkohar/sracipe

Science Score: 10.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
  • codemeta.json file
  • .zenodo.json file
  • DOI references
  • Academic publication links
    Links to: nature.com
  • Committers with academic emails
  • Institutional organization owner
  • JOSS paper metadata
  • Scientific vocabulary similarity
    Low similarity (8.7%) to scientific vocabulary

Keywords

cpp gene gene-circuit-explorer genetics r racipe regulatory-networks simulated-annealing simulation sracipe stochastic
Last synced: 6 months ago · JSON representation

Repository

sRACIPE for bioconductor

Basic Info
Statistics
  • Stars: 0
  • Watchers: 0
  • Forks: 1
  • Open Issues: 1
  • Releases: 0
Topics
cpp gene gene-circuit-explorer genetics r racipe regulatory-networks simulated-annealing simulation sracipe stochastic
Created almost 7 years ago · Last pushed almost 5 years ago
Metadata Files
Readme License

README.md

sRACIPE

Stochastic analysis for Random Circuit Perturbation

sRACIPE implements a randomization-based method for gene circuit modeling. It allows us to study the effect of both the gene expression noise and the parametric variation on any gene regulatory circuit (GRC) using only its topology, and simulates an ensemble of models with random kinetic parameters at multiple noise levels. Statistical analysis of the generated gene expressions reveals the basin of attraction and stability of various phenotypic states and their changes associated with intrinsic and extrinsic noises. sRACIPE provides a holistic picture to evaluate the effects of both the stochastic nature of cellular processes and the parametric variation.

If you use sRACIPE, please consider citing our paper Role of noise and parametric variation in the dynamics of gene regulatory circuits published in npj Systems Biology and Applications.

Installation

if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("sRACIPE")

Or install the github version for new features. This will allow installation of most recent sRACIPE even if you are using older R and Bioconductor.

library(devtools)
install_github(“vivekkohar/sRACIPE”)

Build Reports

  • Bioconductor Release – Bioconductor Release
  • Bioconductor devel – Bioconductor devel

Owner

  • Name: Vivek Kohar
  • Login: vivekkohar
  • Kind: user

GitHub Events

Total
  • Issue comment event: 1
Last Year
  • Issue comment event: 1

Committers

Last synced: over 2 years ago

All Time
  • Total Commits: 39
  • Total Committers: 3
  • Avg Commits per committer: 13.0
  • Development Distribution Score (DDS): 0.179
Past Year
  • Commits: 0
  • Committers: 0
  • Avg Commits per committer: 0.0
  • Development Distribution Score (DDS): 0.0
Top Committers
Name Email Commits
Vivek Kohar v****r@g****m 32
Nitesh Turaga n****a@g****m 4
Vivek Kohar v****r@V****l 3

Issues and Pull Requests

Last synced: 6 months ago

All Time
  • Total issues: 1
  • Total pull requests: 1
  • Average time to close issues: N/A
  • Average time to close pull requests: less than a minute
  • Total issue authors: 1
  • Total pull request authors: 1
  • Average comments per issue: 1.0
  • Average comments per pull request: 0.0
  • Merged pull requests: 1
  • Bot issues: 0
  • Bot pull requests: 0
Past Year
  • Issues: 0
  • Pull requests: 0
  • Average time to close issues: N/A
  • Average time to close pull requests: N/A
  • Issue authors: 0
  • Pull request authors: 0
  • Average comments per issue: 0
  • Average comments per pull request: 0
  • Merged pull requests: 0
  • Bot issues: 0
  • Bot pull requests: 0
Top Authors
Issue Authors
  • LalicJ (1)
Pull Request Authors
  • vivekkohar (1)
Top Labels
Issue Labels
Pull Request Labels

Packages

  • Total packages: 1
  • Total downloads:
    • bioconductor 10,222 total
  • Total dependent packages: 0
  • Total dependent repositories: 0
  • Total versions: 6
  • Total maintainers: 1
bioconductor.org: sRACIPE

Systems biology tool to simulate gene regulatory circuits

  • Versions: 6
  • Dependent Packages: 0
  • Dependent Repositories: 0
  • Downloads: 10,222 Total
Rankings
Dependent repos count: 0.0%
Dependent packages count: 0.0%
Forks count: 19.8%
Average: 24.8%
Stargazers count: 33.2%
Downloads: 71.3%
Maintainers (1)
Last synced: 6 months ago

Dependencies

DESCRIPTION cran
  • R >= 3.6.0 depends
  • Rcpp * depends
  • SummarizedExperiment * depends
  • methods * depends
  • BiocGenerics * imports
  • MASS * imports
  • RColorBrewer * imports
  • S4Vectors * imports
  • ggplot2 * imports
  • gplots * imports
  • grDevices * imports
  • graphics * imports
  • gridExtra * imports
  • htmlwidgets * imports
  • reshape2 * imports
  • stats * imports
  • umap * imports
  • utils * imports
  • visNetwork * imports
  • BiocStyle * suggests
  • doFuture * suggests
  • knitr * suggests
  • rmarkdown * suggests
  • tinytest * suggests