Signac

R toolkit for the analysis of single-cell chromatin data

https://github.com/stuart-lab/signac

Science Score: 59.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
  • codemeta.json file
    Found codemeta.json file
  • .zenodo.json file
    Found .zenodo.json file
  • DOI references
    Found 2 DOI reference(s) in README
  • Academic publication links
    Links to: nature.com
  • Committers with academic emails
    5 of 16 committers (31.3%) from academic institutions
  • Institutional organization owner
  • JOSS paper metadata
  • Scientific vocabulary similarity
    Low similarity (17.0%) to scientific vocabulary

Keywords

atac bioinformatics single-cell

Keywords from Contributors

human-cell-atlas single-cell-genomics single-cell-rna-seq genomics transcriptomics
Last synced: 6 months ago · JSON representation

Repository

R toolkit for the analysis of single-cell chromatin data

Basic Info
Statistics
  • Stars: 385
  • Watchers: 5
  • Forks: 100
  • Open Issues: 22
  • Releases: 21
Topics
atac bioinformatics single-cell
Created almost 7 years ago · Last pushed 6 months ago
Metadata Files
Readme Changelog Contributing License Code of conduct

README.md

Signac

R-CMD-check CRAN
Version CRAN
Downloads

Overview

Signac is a comprehensive R package for the analysis of single-cell chromatin data. Signac includes functions for quality control, normalization, dimension reduction, clustering, differential activity, and more.

Documentation and tutorials can be found at https://stuartlab.org/signac/

Installation

To install the latest release of Signac from CRAN:

r setRepositories(ind=1:3) # needed to automatically install Bioconductor dependencies install.packages("Signac")

To release the latest develop version from GitHub:

r if (!requireNamespace("remotes", quietly = TRUE)) install.packages("remotes") remotes::install_github("stuart-lab/signac", ref = "develop")

Release notes

For a changelog please see the NEWS file, also available on the Signac website.

Contributing

We welcome contributions to the Signac package. Please see the contribution guide for more information.

Getting help

If you encounter a bug or have a feature request, please open an issue.

If you would like to discuss questions related to single-cell analysis, you can open a discussion.

Citing Signac

If you use the Signac package in your work please cite Stuart et al. 2021

@ARTICLE{signac, title = "Single-cell chromatin state analysis with Signac", author = "Stuart, Tim and Srivastava, Avi and Madad, Shaista and Lareau, Caleb A and Satija, Rahul", journal = "Nat. Methods", publisher = "Nature Publishing Group", pages = "1--9", month = nov, year = 2021, url = "https://www.nature.com/articles/s41592-021-01282-5", language = "en" }

Related packages

Owner

  • Name: Stuart Lab
  • Login: stuart-lab
  • Kind: organization

GitHub Events

Total
  • Create event: 1
  • Release event: 1
  • Issues event: 127
  • Watch event: 57
  • Issue comment event: 190
  • Push event: 14
  • Pull request event: 12
  • Fork event: 13
Last Year
  • Create event: 1
  • Release event: 1
  • Issues event: 127
  • Watch event: 57
  • Issue comment event: 190
  • Push event: 14
  • Pull request event: 12
  • Fork event: 13

Committers

Last synced: about 2 years ago

All Time
  • Total Commits: 1,791
  • Total Committers: 16
  • Avg Commits per committer: 111.938
  • Development Distribution Score (DDS): 0.027
Past Year
  • Commits: 139
  • Committers: 5
  • Avg Commits per committer: 27.8
  • Development Distribution Score (DDS): 0.058
Top Committers
Name Email Commits
timoast 4****t 1,742
Saket Choudhary s****c@g****m 11
Avi Srivastava a****a@c****u 6
Avi Srivastava k****i 5
yyan7 y****n@u****u 5
Gesmira g****a@g****m 4
kmwinkley k****y@g****m 4
kmwinkley k****y@h****l 3
Thomas Wayne McCarthy t****y@b****m 2
caleblareau c****u@g****u 2
Caleb Lareau c****u@s****u 2
Nicole Rockweiler n****r@g****m 1
Federico Marini m****f@u****e 1
maxim-h m****v@g****m 1
Ian Driver i****n@g****o 1
Donghoon Lee h****y 1
Committer Domains (Top 20 + Academic)

Issues and Pull Requests

Last synced: 6 months ago

All Time
  • Total issues: 469
  • Total pull requests: 23
  • Average time to close issues: 15 days
  • Average time to close pull requests: 4 months
  • Total issue authors: 335
  • Total pull request authors: 11
  • Average comments per issue: 2.49
  • Average comments per pull request: 2.13
  • Merged pull requests: 10
  • Bot issues: 0
  • Bot pull requests: 0
Past Year
  • Issues: 97
  • Pull requests: 13
  • Average time to close issues: 29 days
  • Average time to close pull requests: 2 months
  • Issue authors: 75
  • Pull request authors: 4
  • Average comments per issue: 0.95
  • Average comments per pull request: 0.92
  • Merged pull requests: 4
  • Bot issues: 0
  • Bot pull requests: 0
Top Authors
Issue Authors
  • KshitijDeoghar (6)
  • kryptonitecircuit2002 (6)
  • emanuelavilla (6)
  • mossconfuse (5)
  • sylestiel (5)
  • linzhangTuesday (5)
  • jgarces02 (4)
  • zgb963 (4)
  • jenellewallace (4)
  • sabrinacamp2 (4)
  • danielcgingerich (4)
  • superSXB (4)
  • yamihn (4)
  • BartBryant (4)
  • Dragonmasterx87 (4)
Pull Request Authors
  • lldelisle (8)
  • cmf1997 (2)
  • Baboon61 (2)
  • jeroen (2)
  • yuanlizhanshi (2)
  • twmccart (2)
  • dstyaaaaaa (1)
  • nrockweiler (1)
  • federicomarini (1)
  • bschilder (1)
  • Gesmira (1)
Top Labels
Issue Labels
bug (168) documentation (107) enhancement (44) question (7) installation (2) duplicate (2)
Pull Request Labels

Packages

  • Total packages: 2
  • Total downloads:
    • cran 5,996 last-month
  • Total docker downloads: 1,690
  • Total dependent packages: 1
    (may contain duplicates)
  • Total dependent repositories: 17
    (may contain duplicates)
  • Total versions: 24
  • Total maintainers: 1
proxy.golang.org: github.com/stuart-lab/signac
  • Versions: 4
  • Dependent Packages: 0
  • Dependent Repositories: 0
Rankings
Dependent packages count: 5.4%
Average: 5.6%
Dependent repos count: 5.8%
Last synced: 6 months ago
cran.r-project.org: Signac

Analysis of Single-Cell Chromatin Data

  • Versions: 20
  • Dependent Packages: 1
  • Dependent Repositories: 17
  • Downloads: 5,996 Last month
  • Docker Downloads: 1,690
Rankings
Forks count: 0.7%
Stargazers count: 1.5%
Downloads: 5.0%
Dependent repos count: 6.9%
Average: 8.9%
Dependent packages count: 18.1%
Docker downloads count: 21.1%
Maintainers (1)
Last synced: 6 months ago

Dependencies

.github/workflows/cmd-check.yml actions
  • actions/cache v2 composite
  • actions/checkout v2 composite
  • actions/upload-artifact master composite
  • r-lib/actions/setup-r v2 composite
DESCRIPTION cran
  • R >= 4.0.0 depends
  • methods * depends
  • BiocGenerics * imports
  • GenomeInfoDb >= 1.29.3 imports
  • GenomicRanges * imports
  • IRanges * imports
  • Matrix * imports
  • Rcpp * imports
  • RcppRoll * imports
  • Rsamtools * imports
  • S4Vectors * imports
  • SeuratObject >= 4.0.0 imports
  • data.table * imports
  • dplyr >= 1.0.0 imports
  • fastmatch * imports
  • future * imports
  • future.apply * imports
  • ggplot2 * imports
  • grid * imports
  • irlba * imports
  • patchwork * imports
  • pbapply * imports
  • scales * imports
  • stats * imports
  • stringi * imports
  • tidyr * imports
  • tidyselect * imports
  • utils * imports
  • vctrs * imports
  • BSgenome * suggests
  • Biostrings * suggests
  • Seurat >= 4.0.6 suggests
  • SummarizedExperiment * suggests
  • TFBSTools * suggests
  • biovizBase * suggests
  • chromVAR * suggests
  • ggforce * suggests
  • ggrepel * suggests
  • ggseqlogo * suggests
  • lsa * suggests
  • miniUI * suggests
  • motifmatchr * suggests
  • qlcMatrix * suggests
  • rtracklayer * suggests
  • shiny * suggests
  • testthat >= 2.1.0 suggests
Dockerfile docker
  • satijalab/seurat latest build