TcGSA

R package for Time-course Gene Set Analysis

https://github.com/sistm/tcgsa

Science Score: 23.0%

This score indicates how likely this project is to be science-related based on various indicators:

  • CITATION.cff file
  • codemeta.json file
  • .zenodo.json file
  • DOI references
    Found 3 DOI reference(s) in README
  • Academic publication links
  • Committers with academic emails
    4 of 10 committers (40.0%) from academic institutions
  • Institutional organization owner
  • JOSS paper metadata
  • Scientific vocabulary similarity
    Low similarity (13.7%) to scientific vocabulary
Last synced: 10 months ago · JSON representation

Repository

R package for Time-course Gene Set Analysis

Basic Info
Statistics
  • Stars: 6
  • Watchers: 3
  • Forks: 2
  • Open Issues: 2
  • Releases: 0
Created about 12 years ago · Last pushed 12 months ago
Metadata Files
Readme License

README.Rmd

---
output: github_document
---



```{r, echo = FALSE}
knitr::opts_chunk$set(
  collapse = TRUE,
  comment = "#>",
  fig.path = "README-"
)
```


# `TcGSA`

[![CRAN_Status_Badge](http://www.r-pkg.org/badges/version/TcGSA)](https://cran.r-project.org/package=TcGSA)
[![R-CMD-check](https://github.com/sistm/TcGSA/actions/workflows/R-CMD-check.yaml/badge.svg)](https://github.com/sistm/TcGSA/actions/workflows/R-CMD-check.yaml)
[![Downloads](https://cranlogs.r-pkg.org/badges/TcGSA?color=blue)](https://www.r-pkg.org/pkg/TcGSA)

## Overview

`TcGSA` is a package which performs *Time-course Gene Set Analysis* from **microarray data**, and provide nice representations of its results.

On top of the CRAN help pdf-file, the following article explains what TcGSA is about:

>Hejblum, BP, Skinner, J, & Thiébaut, R (2015). Time-Course Gene Set Analysis for Longitudinal Gene Expression Data. *PLOS Computational Biology*, **11**(6):e1004310. [](https://doi.org/10.1371/journal.pcbi.1004310)



## Installation


TcGSA imports the `multtest` package which is not available on [CRAN](https://cran.r-project.org/), but is available on the [Bioconductor](https://www.bioconductor.org/packages/release/bioc/html/multtest.html) repository.
Before installing TcGSA, be sure to have this `multtest` package installed. If not, you can do so by running the following:

```{r bioc-install, eval=FALSE}
if (!requireNamespace("BiocManager", quietly = TRUE)) {
    install.packages("BiocManager")
}
BiocManager::install("multtest")
```

The easiest way to get `TcGSA` is to install it from [CRAN](https://cran.r-project.org/package=TcGSA):
```{r CRAN-install, eval=FALSE}
install.packages("TcGSA")
```

or to get the development version from [GitHub](https://github.com/sistm/TcGSA/):
```{r GitHub-install, eval=FALSE}
#install.packages("devtools")
devtools::install_github("sistm/TcGSA")
```

## Microarrays vs RNA-seq

`TcGSA` relies on a Gaussian assumption for the expression data, which is suitable for 
normalized microarray data. Due to their count and heteroskedastic nature, RNA-seq
data need to be handled differently and ***TcGSA cannot deal with RNA-seq data***.
For RNA-seq data, please have a look at the [Bioconductor package `dearseq`](https://bioconductor.org/packages/dearseq/) 
which incorporates similar functionalities for analyzing RNA-seq data.

 -- Boris Hejblum

Owner

  • Name: SISTM
  • Login: sistm
  • Kind: organization
  • Location: Bordeaux, france

research team from Inserm BPH U1219 & Inria BSO

GitHub Events

Total
  • Watch event: 3
  • Push event: 21
Last Year
  • Watch event: 3
  • Push event: 21

Committers

Last synced: over 2 years ago

All Time
  • Total Commits: 223
  • Total Committers: 10
  • Avg Commits per committer: 22.3
  • Development Distribution Score (DDS): 0.596
Past Year
  • Commits: 0
  • Committers: 0
  • Avg Commits per committer: 0.0
  • Development Distribution Score (DDS): 0.0
Top Committers
Name Email Commits
Boris b****i@g****m 90
Boris Hejblum b****m@i****m 35
borishejblum b****h@g****m 31
borishejblum b****m@i****r 27
borishejblum b****m@u****r 24
damienchimits d****s@g****m 5
borishejblum b****m@s****u 5
borishejblum b****h@g****m 3
Boris B****s@m****l 2
anthonydevaux 3****x 1
Committer Domains (Top 20 + Academic)

Issues and Pull Requests

Last synced: 11 months ago

All Time
  • Total issues: 15
  • Total pull requests: 9
  • Average time to close issues: 4 months
  • Average time to close pull requests: 17 days
  • Total issue authors: 13
  • Total pull request authors: 3
  • Average comments per issue: 3.6
  • Average comments per pull request: 0.11
  • Merged pull requests: 6
  • Bot issues: 0
  • Bot pull requests: 0
Past Year
  • Issues: 0
  • Pull requests: 0
  • Average time to close issues: N/A
  • Average time to close pull requests: N/A
  • Issue authors: 0
  • Pull request authors: 0
  • Average comments per issue: 0
  • Average comments per pull request: 0
  • Merged pull requests: 0
  • Bot issues: 0
  • Bot pull requests: 0
Top Authors
Issue Authors
  • PFRoux (2)
  • mimisikai (2)
  • jcfoo (1)
  • friedue (1)
  • stuomiva (1)
  • ShuyiGan (1)
  • Biofarmer (1)
  • elcega (1)
  • dzhakparov (1)
  • mchimenti (1)
  • mebbert (1)
  • emilyleventhal (1)
  • saraa30 (1)
Pull Request Authors
  • damienchimits (6)
  • borishejblum (2)
  • anthonydevaux (1)
Top Labels
Issue Labels
help wanted (5) question (3) bug (2) enhancement (2)
Pull Request Labels
enhancement (1)

Packages

  • Total packages: 1
  • Total downloads:
    • cran 330 last-month
  • Total docker downloads: 21,613
  • Total dependent packages: 0
  • Total dependent repositories: 0
  • Total versions: 9
  • Total maintainers: 1
cran.r-project.org: TcGSA

Time-Course Gene Set Analysis

  • Versions: 9
  • Dependent Packages: 0
  • Dependent Repositories: 0
  • Downloads: 330 Last month
  • Docker Downloads: 21,613
Rankings
Forks count: 17.8%
Stargazers count: 24.2%
Dependent packages count: 29.8%
Average: 31.5%
Dependent repos count: 35.5%
Downloads: 50.4%
Maintainers (1)
Last synced: 11 months ago

Dependencies

DESCRIPTION cran
  • R >= 3.0.2 depends
  • ggplot2 >= 2.0.0 depends
  • GSA * imports
  • cluster * imports
  • cowplot * imports
  • grDevices * imports
  • graphics * imports
  • gtools * imports
  • lme4 >= 1.0 imports
  • multtest * imports
  • reshape2 * imports
  • splines * imports
  • stats * imports
  • stringr * imports
  • utils * imports
  • BiocManager * suggests
  • GEOquery * suggests
  • dearseq * suggests
  • doParallel * suggests
  • foreach * suggests
  • knitr * suggests
  • parallel * suggests
  • rmarkdown * suggests