peptoolkit

A Toolkit for Using Peptide Sequences in Machine Learning and Accelerate Virtual Screening

https://github.com/jrcodina/peptoolkit

Science Score: 13.0%

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Repository

A Toolkit for Using Peptide Sequences in Machine Learning and Accelerate Virtual Screening

Basic Info
  • Host: GitHub
  • Owner: jrcodina
  • License: gpl-3.0
  • Language: R
  • Default Branch: master
  • Size: 59.6 KB
Statistics
  • Stars: 0
  • Watchers: 1
  • Forks: 0
  • Open Issues: 0
  • Releases: 0
Created almost 3 years ago · Last pushed over 2 years ago
Metadata Files
Readme License

README.md

PepToolkit

The peptoolkit R package is designed for the manipulation and analysis of peptides sequences. It provides functionalities to assist researchers in peptide engineering and proteomics. Users can manipulate peptides by adding amino acids at every position, count occurrences of each amino acid at each position, and transform amino acid counts based on probabilities. The package offers functionalities to select the best versus the worst peptides and analyze these peptides, which includes counting specific residues, reducing peptide sequences, extracting features through One Hot Encoding (OHE), and utilizing Quantitative Structure-Activity Relationship (QSAR) properties (based in the package 'Peptides' by Osorio et al. (2015) doi:10.32614/RJ-2015-001). This package is intended for both researchers and bioinformatics enthusiasts working on peptide-based projects, especially for their use with machine learning.

Installation

You can install the released version of peptoolkit (0.0.1) from CRAN with:

r install.packages("peptoolkit")

You can also install the development version (0.0.2) from GitHub with:

```r

install.packages("devtools") # Uncomment and run if you don't have the devtools package yet

devtools::install_github("jrcodina/peptoolkit") ```

Example

This is a basic example which shows you how to use the main function:

```r

Default usage

result <- peptoolkit::extractfeaturesQSAR(n = 3)

Providing a custom peptide list

result <- peptoolkit::extractfeaturesQSAR(n = 3, custom.list = TRUE, PeList = c('ACA', 'ADE')) ```

Please refer to function documentation for more details on parameters and their usage.

Citation

If you use peptoolkit in your research, please cite:

Codina J (2023). peptoolkit: A Toolkit for Using Peptide Sequences in Machine Learning and Accelerate Virtual Screening. R package version 0.0.1.

A BibTeX entry for LaTeX users is

@Manual{, title = {peptoolkit: A Toolkit for Using Peptide Sequences in Machine Learning and Accelerate Virtual Screening}, author = {Josep-Ramon Codina}, year = {2023}, note = {R package version 0.0.1}, }

Owner

  • Name: Josep Ramón Codina García-Andrade
  • Login: jrcodina
  • Kind: user
  • Location: Miami, Florida, USA
  • Company: Miller School of Medicine, University of Miami

Ph.D student BIochemistry and Molecular Biology. Biotechnology major and Masters of Pharmacy, learning Data Analysis.

GitHub Events

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  • Total packages: 1
  • Total downloads:
    • cran 185 last-month
  • Total dependent packages: 0
  • Total dependent repositories: 0
  • Total versions: 1
  • Total maintainers: 1
cran.r-project.org: peptoolkit

A Toolkit for Using Peptide Sequences in Machine Learning

  • Versions: 1
  • Dependent Packages: 0
  • Dependent Repositories: 0
  • Downloads: 185 Last month
Rankings
Forks count: 28.4%
Dependent packages count: 28.8%
Dependent repos count: 34.5%
Stargazers count: 34.9%
Average: 43.0%
Downloads: 88.5%
Maintainers (1)
Last synced: 10 months ago

Dependencies

DESCRIPTION cran
  • R >= 4.3.0 depends
  • caret * depends
  • Peptides * imports
  • dplyr * imports
  • stats * imports
  • stringr * imports