Science Score: 26.0%
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○Scientific vocabulary similarity
Low similarity (7.1%) to scientific vocabulary
Repository
Implementation of Shiny apps to visualize adverse events.
Basic Info
- Host: GitHub
- Owner: dnzmarcio
- License: gpl-2.0
- Language: R
- Default Branch: master
- Size: 462 KB
Statistics
- Stars: 1
- Watchers: 2
- Forks: 2
- Open Issues: 0
- Releases: 1
Metadata Files
README.md
Visualizing Adserve Events
The R package visae implements 'shiny' apps to visualize adverse events (AE) based on the Common Terminology Criteria for Adverse Events (CTCAE).
Installation
r
instal.packages("visae")
The latest version can be installed from GitHub as follows:
r
devtools::install_github("dnzmarcio/visae")
Stacked Correspondence Analysis
Generating minimal dataset
```r patientid <- 1:4000 group <- c(rep("A", 1000), rep("B", 1000), rep("C", 1000), rep("D", 1000)) aegrade <- c(rep("AE class 01", 600), rep("AE class 02", 300), rep("AE class 03", 100), rep("AE class 04", 0), rep("AE class 01", 100), rep("AE class 02", 400), rep("AE class 03", 400), rep("AE class 04", 100), rep("AE class 01", 233), rep("AE class 02", 267), rep("AE class 03", 267), rep("AE class 04", 233), rep("AE class 01", 0), rep("AE class 02", 100), rep("AE class 03", 300), rep("AE class 04", 600))
dt <- tibble(patientid = patientid, trt = group, aeg = aegrade) ```
Investigating different CA configurations using the Shiny application
r
library(visae)
library(magrittr)
library(dplyr)
dt %>% run_ca(., group = trt,
id = patient_id,
ae_grade = ae_g)
Plotting CA biplot as ggplot object
r
ca <- dt %>% ca_ae(., group = trt,
id = patient_id,
ae_class = ae_g,
contr_indicator = FALSE,
mass_indicator = TRUE,
contr_threshold = 0,
mass_threshold = 0)
ca$asymmetric_plot
Interpreting biplots for Correspondence Analysis
Investigators often interpret CA biplots erroneously assuming that the distance between AE classes dots and treatments dots is an indicative of association. See step by step to interpret biplots correctly are below:
1. Minimum example dataset

2. Interpreting percentage of explained variability by dimensions, center average treatment and AE dot sizes

3. Interpreting dimensions and associations between treatments and AEs

4. Comparing treatments and avoiding misleading interpretations

References
Owner
- Name: Marcio Augusto Diniz
- Login: dnzmarcio
- Kind: user
- Location: Los Angeles, CA
- Repositories: 19
- Profile: https://github.com/dnzmarcio
Ph.D. in Statistics. R Enthusiastic. Bayesian.
GitHub Events
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Last Year
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- Fork event: 1
Committers
Last synced: over 2 years ago
Top Committers
| Name | Commits | |
|---|---|---|
| Marcio Augusto Diniz | d****o@g****m | 31 |
| dnzmarcio | m****z@c****g | 16 |
| Diniz | M****z@c****g | 5 |
Committer Domains (Top 20 + Academic)
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Last synced: 11 months ago
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Packages
- Total packages: 1
-
Total downloads:
- cran 191 last-month
- Total dependent packages: 0
- Total dependent repositories: 0
- Total versions: 3
- Total maintainers: 1
cran.r-project.org: visae
Visualization of Adverse Events
- Documentation: http://cran.r-project.org/web/packages/visae/visae.pdf
- License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
-
Latest release: 0.2.1
published over 1 year ago
Rankings
Maintainers (1)
Dependencies
- dplyr >= 1.0.0 depends
- ggplot2 >= 3.3.0 depends
- magrittr >= 1.5.0 depends
- shiny >= 1.4.0 depends
- DT >= 0.13 imports
- ca >= 0.71 imports
- ggrepel >= 0.8.2 imports
- rlang >= 0.4.6 imports
- shinyjs >= 1.1 imports
- tidyr >= 1.1.0 imports
- knitr * suggests
- rmarkdown * suggests
- r-hub/actions/checkout v1 composite
- r-hub/actions/platform-info v1 composite
- r-hub/actions/run-check v1 composite
- r-hub/actions/setup v1 composite
- r-hub/actions/setup-deps v1 composite
- r-hub/actions/setup-r v1 composite