mixedbayes
Bayesian Longitudinal Regularized Quantile Mixed Model
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Bayesian Longitudinal Regularized Quantile Mixed Model
Statistics
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Metadata Files
README.md
mixedBayes
Bayesian Longitudinal Regularized Quantile Mixed Model <!-- badges: start -->
With high-dimensional omics features, repeated measure ANOVA leads to longitudinal gene-environment interaction studies that have intra-cluster correlations, outlying observations and structured sparsity arising from the ANOVA design. In this package, we have developed robust sparse Bayesian mixed effect models tailored for the above studies (Fan et al. (2025)). An efficient Gibbs sampler has been developed to facilitate fast computation. The Markov chain Monte Carlo algorithms of the proposed and alternative methods are efficiently implemented in 'C++'. The development of this software package and the associated statistical methods have been partially supported by an Innovative Research Award from Johnson Cancer Research Center, Kansas State University.
How to install
- To install from github, run these two lines of code in R
install.packages("devtools")
devtools::install_github("kunfa/mixedBayes")
- Released versions of mixedBayes are available on CRAN (link), and can be installed within R via
install.packages("mixedBayes")
Examples
Example.1 (default method: robust sparse bi-level selection under random intercept -and- slope model)
library(mixedBayes)
data(data)
fit = mixedBayes(y,e,X,g,w,k,structure=c("bi-level"))
fit$coefficient
b = selection(fit,sparse=TRUE)
index = which(coeff!=0)
pos = which(b != 0)
tp = length(intersect(index, pos))
fp = length(pos) - tp
list(tp=tp, fp=fp)
Example.2 (alternative: robust sparse individual level selection under random intercept -and- slope model)
fit = mixedBayes(y,e,X,g,w,k,structure=c("individual"))
fit$coefficient
b = selection(fit,sparse=TRUE)
index = which(coeff!=0)
pos = which(b != 0)
tp = length(intersect(index, pos))
fp = length(pos) - tp
list(tp=tp, fp=fp)
Example.3 (alternative: non-robust sparse bi-level selection under random intercept -and- slope model)
fit = mixedBayes(y,e,X,g,w,k,robust=FALSE, structure=c("bi-level"))
fit$coefficient
b = selection(fit,sparse=TRUE)
index = which(coeff!=0)
pos = which(b != 0)
tp = length(intersect(index, pos))
fp = length(pos) - tp
list(tp=tp, fp=fp)
Example.4 (alternative: robust sparse bi-level selection under random intercept model)
fit = mixedBayes(y,e,X,g,w,k,slope=FALSE, structure=c("bi-level"))
fit$coefficient
b = selection(fit,sparse=TRUE)
index = which(coeff!=0)
pos = which(b != 0)
tp = length(intersect(index, pos))
fp = length(pos) - tp
list(tp=tp, fp=fp)
Methods
This package provides implementation for methods proposed in
- Fan, K., Jiang, Y., Ma, S., Wang, W. and Wu, C. (2025). Robust Sparse Bayesian Regression for Longitudinal Gene-Environment Interactions. Journal of the Royal Statistical Society Series C: Applied Statistics, qlaf027
Owner
- Name: Kun Fan
- Login: kunfa
- Kind: user
- Location: Manhattan, KS
- Company: Kansas State University
- Repositories: 1
- Profile: https://github.com/kunfa
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cran.r-project.org: mixedBayes
Bayesian Longitudinal Regularized Quantile Mixed Model
- Homepage: https://github.com/kunfa/mixedBayes
- Documentation: http://cran.r-project.org/web/packages/mixedBayes/mixedBayes.pdf
- License: GPL-2
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Latest release: 0.1.11
published 10 months ago