Projects

Updated 10 months ago

herg-binding-mechanisms • Rank 0.7 • Science 13%

Source code and data for reproducing "The impact of uncertainty in hERG binding mechanism on in silico predictions of drug-induced proarrhythmic risk".

drug-binding drug-induced-arrhythmias herg in-silico uncertainty

Updated 10 months ago

https://github.com/cardiacmodelling/rapidcharacterisationprotocols • Science 13%

Collection of experimental protocols in common patch clamp formats for rapid characterisation of ion channels

electrophysiology herg ion-channel-kinetics ion-channels patch-clamp voltage-clamp

Updated 10 months ago

https://github.com/cardiacmodelling/hergrapidcharacterisation • Science 13%

Rapid characterisation of hERG channel kinetics

electrophysiology herg herg-channel-kinetics high-throughput ion-channels modeling patch-clamp temperature-dependence voltage-clamp

Updated 10 months ago

neural-ode-ion-channels • Science 23%

Code and figures for "Neural network differential equations for ion channel modelling".

electrophysiology herg ion-channel-kinetics model-discrepancy neural-networks neural-ode

Updated 10 months ago

voltageclampmodel • Science 39%

Code to add a mathematical model of voltage-clamp artefacts to your ion channel simulations

artefacts electrophysiology herg high-throughput ion-channel-kinetics modeling patch-clamp variability voltage-clamp

Updated 10 months ago

https://github.com/cardiacmodelling/markov-builder • Science 13%

Tool for building and manipulating Markov models of ion-channel kinetics

herg herg-channel-kinetics markov-model python

ecosyste.ms

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Experiments

Open Source Science

herg-binding-mechanisms • Rank 0.7 • Science 13%

https://github.com/cardiacmodelling/rapidcharacterisationprotocols • Science 13%

https://github.com/cardiacmodelling/hergrapidcharacterisation • Science 13%

neural-ode-ion-channels • Science 23%

voltageclampmodel • Science 39%

https://github.com/cardiacmodelling/markov-builder • Science 13%